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    Editorial

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    Dear Colleagues,it is a pleasure to introduce the present issue of Ultrasound International Open 2018.</jats:p

    Editorial

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    Dear Colleagues, It is a pleasure to introduce the present issue of Ultrasound International Open. It contains an updated overview of how handling ultrasound systems, fundamental adjustments, and their optimization in B-mode ultrasound provided by Dr. Zander and colleagues

    CEUS: where are we in 2015?

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    Contrast enhanced ultrasound (CEUS), performed with the intravenous injection of microbubble contrast agents, has expanded the horizon for ultrasound imaging by providing a technique with superb sensitivity to arterial phase enhancement in dynamic realtime. For the first time, demonstration of blood flow at the microcirculatory or perfusion level is possible on ultrasound. Further, the purely intravascular microbubbles allow ultrasound to be used to monitor changes in the blood flow to tumors and in inflammatory sites. Its safe performance without any requirement for ionizing radiation and with no nephrotoxicity makes it a compelling choice in many clinical arenas and certainly for children. Here, we describe the wide and growing uses of CEUS in abdominal imaging

    Ultrasound, the handyman serving our whole populations in the post COVID-19 pandemic

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    Since the introduction of the B-mode technology around 40 years ago the evolution of ultrasonography has been greatest and has surpassed the evolution of other imaging methods such as Computed Tomography or Magnetic Resonance from some points of view. Ultrasound now spans through an extremely wide range of regular uses, covering needs of the entire spectrum of our citizens. The articles published in this issue of the journal are a very illustrative example of such versatility. For instance, if we consider the ages of the population, these articles show how ultrasound is regularly utilized with great benefit at any time of the human life. Its use spans from the very early times, like the prenatal intrauterine conditions, moving to the perinatal period, the adult life, times at which CT or MRI are scantly of any use and finally to the disease of the elderly, such as Alzheimer’s dementia

    Different techniques for ultrasound liver elastography

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    No abstract is to provided with the types of articles to which this publication belongs (sort of Editorial or Brief commentary). Actually it is a brief graphical summary of medical situation

    Acoustic radiation force impulse elastography for liver iron overload in β‐thalassemia major: Is it going to cut it?

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    In this issue ofJCU, Kaban and Damar investigated the correlationand agreement between T2*-weighted MRI, ARFI measurementresults of liver and plasma ferritin levels in 40 pediatric patients withβ-thalassemia. The authors demonstrated a strong negative correla-tion between T2*-weighted MRI and ARFI measurement, a moderatenegative correlation between T2*-weighted MRI and plasma ferritinlevels, and a strong positive correlation between ARFI values andplasma ferritin levels. The results of this article differ from theresults of the study by Wurschli et al. possibly due to the different populations: while Kaban et al. investigated patients withβ-thalasse-mia, Wurschli et al. investigated patients who had undergone bonemarrow transplant, which are prone to suffer from additional causesof liver injury, including graft versus host disease, sinusoid obstructionsyndrome, and drug induced liver disease. Although the data stemming from this study are still insufficient to propose the use of ARFI as a diagnostic technique to monitor ironoverload in patients withβ-thalassemia, this article is a step towardfurther expanding the potential applications of elastography
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