168 research outputs found
Stillbirths at Term : Case Control Study of Risk Factors, Growth Status and Placental Histology
Get PDFObjective: To investigate the proportion of stillbirths at term associated with abnormal growth using customized birth weight percentiles and to compare histological placental findings both in underweight stillborn fetuses and in live births. Methods: A retrospective case-control study of 150 singleton term stillbirths. The livebirth control groups included 586 cases of low-risk pregnancies and 153 late fetal growth restriction fetuses. Stillbirths and livebirths from low-risk pregnancies were classified using customized standards for fetal weight at birth, as adequate for gestational age (AGA; 10-90th percentile), small (SGA; 90th percentile). Placental characteristics in stillbirth were compared with those from livebirths using four categories: inflammation, disruptive, obstructive and adaptive lesions. Results: There was a higher rate of SGA (26% vs 6%, p<0.001) and LGA fetuses (10.6% vs 5.6%, p<0.05) in the stillbirth group. Among stillbirth fetuses, almost half of the SGA were very low birthweight (≤3°percentile) (12% vs 0.3%, p<0.001). The disruptive (7.3% vs 0.17%; p<0.001), obstructive (54.6% vs 7.5%;p<0.001) and adaptive (46.6% vs 35.8%;p<0.001) findings were significantly more common in than in livebirth-low risk. Placental characteristics of AGA and SGA stillbirth were compared with those of AGA and FGR livebirth. In stillbirths-SGA we found a higher number of disruptive (12.8% vs 0%; p<0.001), obstructive (58.9% vs 23.5%;p<0.001) and adaptive lesions (56.4% vs 49%; p 0.47) than in livebirth-FGR. Conclusion: The assessment of fetal weight with customized curves can identify fetuses which have not reached their genetically determined growth potential and are therefore at risk for adverse outcomes. Placental evaluation in stillbirths can reveal chronic histological signs that might be useful to clinical assessment, especially in underweight fetuses. © 2016 Mecacci et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
In tema di maltrattamento fisico su minore: considerazioni medico-legali su cinque casi verificatisi a Milano
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The First Commentary on L. S. Vygotsky’s Papers at the II All-Russian Congress of Psychoneurology in Petrograd (January 1924)
No full textAt the Second All-Russian Congress on Psychoneurology in Petrograd (January 1924), Vygotsky delivered three papers. The first paper (“Methodology of Reflexological and Psychological Research”), was printed separately, but the text of the other two reports (“How Psychology Should Be Taught Now” and “Results of a Questionnaire on the Moods of Students of the Graduating Classes of the Gomel Schools in 1923”) has not survived. A brief account of these two reports, which appeared in the magazine Krasnaya Nov’ in 1924, is reprinted here for the first time. The author was the revolutionary M.I. Ginzburg (1877-1940), a researcher at the Moscow Psychological Institute in the mid-1920s. He wrote under the pseudonym G. Dayan. Ginzburg-Dayan was severely criticised in 1935 on charges of Trotskyism.</p
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