559 research outputs found
CCDC 1995084: Experimental Crystal Structure Determination
No full textRelated Article: Nittert Marinus, Nabil Tahiri, Margherita Duca, L. M. C. Marc Mouthaan, Simona Bianca, Marco van den Noort, Bert Poolman, Martin D. Witte, Adriaan J. Minnaard|2020|Org.Lett.|22|5622|doi:10.1021/acs.orglett.0c0198
CCDC 1995088: Experimental Crystal Structure Determination
No full textRelated Article: Nittert Marinus, Nabil Tahiri, Margherita Duca, L. M. C. Marc Mouthaan, Simona Bianca, Marco van den Noort, Bert Poolman, Martin D. Witte, Adriaan J. Minnaard|2020|Org.Lett.|22|5622|doi:10.1021/acs.orglett.0c0198
CCDC 1995088: Experimental Crystal Structure Determination
No full textRelated Article: Nittert Marinus, Nabil Tahiri, Margherita Duca, L. M. C. Marc Mouthaan, Simona Bianca, Marco van den Noort, Bert Poolman, Martin D. Witte, Adriaan J. Minnaard|2020|Org.Lett.|22|5622|doi:10.1021/acs.orglett.0c0198
CCDC 1995084: Experimental Crystal Structure Determination
No full textRelated Article: Nittert Marinus, Nabil Tahiri, Margherita Duca, L. M. C. Marc Mouthaan, Simona Bianca, Marco van den Noort, Bert Poolman, Martin D. Witte, Adriaan J. Minnaard|2020|Org.Lett.|22|5622|doi:10.1021/acs.orglett.0c0198
On the osmotic signal and osmosensing mechanism of an ABC transport system
No full textWat verandert er in het zenuwstelsel als een dier iets leert? Hoe worden herinneringen opgeslagen in de hersenen? Hieraan ten grondslag ligt het vermogen
van het zenuwstelsel om zich aan wisselende omstandigheden aan te passen, of, met andere woorden, plastisch te zijn. Zoals elk orgaan zijn onze hersenen opgebouwd uit afzonderlijke cellen, de hersencellen ofwel neuronen. De werking van de hersenen berust op de communicatie tussen de neuronen. De communicatie vindt
plaats op plaatsen waar de membranen van neuronen heel dicht bij elkaar liggen, de zogenaamde synapsen...
Zie: Chapter 8
CORRECTION: The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter (vol 106, pg 1778, 2009)
No full textBIOCHEMISTRY Correction for “The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter,” by Christopher Mulligan, Eric R. Geertsma, Emmanuele Severi, David J. Kelly, Bert Poolman, and Gavin H. Thomas, which appeared in issue 6, February 10, 2009, of Proc Natl Acad Sci USA (106:1778–1783; first published January 28, 2009; 10.1073/pnas.0809979106).The authors note that due to a printer's error, on page 1782, the equations in Fig. 5 were missing the F constant. The corrected figure and its legend appear below.Fig. 5.Download figure Open in new tab Download powerpointFig. 5.Model of Na+-dependent transport of sialic acid by SiaPQM. The Upper image (Import Cycle) shows the uptake of sialic acid (denoted as asterisk), driven by a (electro)chemical Na+ gradient (ΔμNa + FΔΨ; F, Faraday constant). After binding of sialic acid (asterisk) to SiaP, the liganded complex docks onto SiaQM. A minimum of two sodium ions (black dots) bind to the complex and drive the translocation of sialic acid across the membrane; the sodium ions are cotransported with sialic acid, after which the system relaxes back to the initial conformation. The Lower image (Export Cycle) shows the efflux of sialic acid under conditions that an excess of unliganded SiaP is available. The critical point is that efflux of sialic acid only occurs when unliganded SiaP docks onto SiaQM with bound substrate. Assuming tight coupling in the transport reaction, two or more Na+ ions will be exported together with sialic acid
Energy transduction in lactic acid bacteria
No full textIn the discovery of some general principles of energy transduction, lactic acid bacteria have played an important role. In this review, the energy transducing processes of lactic acid bacteria are discussed with the emphasis on the major developments of the past 5 years. This work not only includes the biochemistry of the enzymes and the bioenergetics of the processes, but also the genetics of the genes encoding the energy transducing proteins. The progress in the area of carbohydrate transport and metabolism is presented first. Sugar translocation involving ATP-driven transport, ion-linked cotransport, heterologous exchange and group translocation are discussed. The coupling of precursor uptake to product product excretion and the linkage of antiport mechanisms to the deiminase pathways of lactic acid bacteria is dealt with in the second section. The third topic relates to metabolic energy conservation by chemiosmotic processes. There is increasing evidence that precursor/product exchange in combination with precursor decarboxylation allows bacteria to generate additional metabolic energy. In the final section transport of nutrients and ions as well as mechanisms to excrete undesirable (toxic) compounds from the cells are discussed.
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