1,721,014 research outputs found
Ulcerative necrobiosis lipoidica successfully treated by vacuum-assisted closure therapy
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Surgery of venous leg ulcers - wound infections with perioperofive antibiotic prophylaxis based on the preoperotive antibiogram
No full textAim: We are presenting the rate of wound infections after surgery of venous leg ulcers in the department of dermatology/University of Goettingen. Moreover, the preoperative contamination with pathogenic microorganisms of the pretreated patients under inpatient conditions is described. Methods: 59 patients with venous leg ulcers were treated with 95 surgical interventions (46 patients one leg, 13 patients both legs; 7 5 epifascial procedures, 20 crural fasciotomies). All patients received a perioperative antibiotic prophylaxis (PAP) based on the preoperative resistance determination. Results: Preoperatively, we found in most cases Staphylococcus aureus on the ulcers, followed by Proteus mirabilis. Three patients (5.1%) were contaminated with methicillin-resistant Staphylococcus aureus (MRSA). Cefazolin and ciprofloxacin were used as PAP in most cases. Five of the 59 patients (8.5%) developed a postoperative wound infection. In three of these cases the preoperative pathological bacteria caused the wound infection. Conclusion: The rate of postoperative wound infections after surgical therapy of venous leg ulcers with the regimen of PAP, based on the preoperative resistance determination, is very acceptable
Successful use of vacuum-assisted closure therapy for leg ulcers caused by occluding vasculopathy and inflammatory vascular diseases - A case series
No full textBackground: Leg ulcers caused by vasculitis, small vessel occlusion or other rare conditions often prove to be very difficult to treat. Despite polypragmatic, systemic and localized therapy, many of these wounds are progressive and characterized by severe pain. Methods and Results: We here portray the cases of 5 patients with ulcers resistant to systemic therapy for the underlying disease, who were treated successfully using vacuum-assisted closure ( VAC) for wound management. We present the advantages and disadvantages of this method, as well as illustrating the essential and known therapeutic principles. Conclusions: Our experience shows VAC to be an excellent and effective alternative in the treatment of therapy-resistant chronic wounds caused by vasculopathy (small vessel occlusion or vasculitis). We did not observe any pathergy or proinflammatory effects caused by VAC. Copyright (c) 2007 S. Karger AG, Base
Surgery of venous leg ulcers - wound infections with perioperofive antibiotic prophylaxis based on the preoperotive antibiogram
No full textAim: We are presenting the rate of wound infections after surgery of venous leg ulcers in the department of dermatology/University of Goettingen. Moreover, the preoperative contamination with pathogenic microorganisms of the pretreated patients under inpatient conditions is described. Methods: 59 patients with venous leg ulcers were treated with 95 surgical interventions (46 patients one leg, 13 patients both legs; 7 5 epifascial procedures, 20 crural fasciotomies). All patients received a perioperative antibiotic prophylaxis (PAP) based on the preoperative resistance determination. Results: Preoperatively, we found in most cases Staphylococcus aureus on the ulcers, followed by Proteus mirabilis. Three patients (5.1%) were contaminated with methicillin-resistant Staphylococcus aureus (MRSA). Cefazolin and ciprofloxacin were used as PAP in most cases. Five of the 59 patients (8.5%) developed a postoperative wound infection. In three of these cases the preoperative pathological bacteria caused the wound infection. Conclusion: The rate of postoperative wound infections after surgical therapy of venous leg ulcers with the regimen of PAP, based on the preoperative resistance determination, is very acceptable
Atypical Location of Lymphocytoma Cutis in a Child
No full textLyme borreliosis is a common infectious disease that can affect myocardial muscle or the central nervous system if not treated at an early stage. Here we report a unique case of an atypical location of lymphocytoma cutis in a 3-year-old boy. Histologic and immunohistochemical analysis revealed the correct diagnosis
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