1,721,108 research outputs found
Applying the MRI BI-RADS in a High-Risk Population
The American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS) has been very early used for the interpretation of breast MRI, also in high-risk women. In the general population, the application of the BI-RADS allowed for a very good diagnostic performance, although associated with rather low inter-reader agreement. This good performance was seen also for the application of the BI-RADS lexicon in screening high-risk women. Cancer in high-risk women can present with relatively subtle features on mammography or ultrasound, but MRI features of malignancy according to the BI-RADS lexicon are found in the vast majority of the cases and allow for a correct management. Some issues still have to be considered. First, for probably benign findings (BI-RADS 3), the lexicon fails to define exactly the lesion characteristics. Furthermore, areas of non-mass enhancement and foci can create problems regarding their best management in high-risk women. Finally, background parenchymal enhancement is usually easy to recognize, and it does not hide suspicious lesions but, in some cases, can be difficult to interpret and a short-term follow-up may be necessary
Risonanza Magnetica del gomito: ottimizzazione della tecnica e definizione degli aspetti normali e delle varianti.
Risonanza Magnetica del gomito: ottimizzazione della tecnica e definizione degli aspetti normali e delle varianti.
Pathological outcome of sonographically occult architectural distortions (AD) visible only on digital breast tomosynthesis, and comparison with AD visible also on 2D mammography
Purpose: To evaluate the rates of malignant and of high-risk lesions among sonographically occult architectural distortions (AD) visible only on digital breast tomosynthesis (DBT) and compare them with AD visible on 2D mammography (2D) and DBT. Method: The records of 1104 DBT-vacuum assisted biopsies (DBT-VAB) were retrospectively reviewed and 218 cases of AD were identified. Complete radiologic examinations and pathologic results were available for 113 sonographically occult AD (1 clinically-detected, 112 clinically-occult). 2D and DBT images were reviewed and AD were divided into a “DBT-detected” group (visible on only DBT) and a “2D-detected” group (visible both in 2D and DBT). The rates of malignant and of high-risk lesions in the “DBT-detected” AD group were calculated and compared to those of the “2D-detected” AD group. Results: Thirty-five (31%) of 113 AD were assessed as “DBT-detected”, while 78 (69%) as “2D-detected”. DBT-VAB results were benign lesions in 63 (56%) AD, high-risk lesions in 32 (28%) AD and malignant lesions in 18 (16%) AD. Four (12.5%) high-risk lesions were upgraded to malignancy at surgery. Based on final pathology, the malignancy rate was significantly higher in the “DBT-detected” group than the “2D-detected” group (34% [12/35 cases] vs 13% [10/78]; p 0.05). Conclusions: AD visible on only DBT proved to be malignant in about one third of cases, which exceeded the malignancy rate of AD visible on also 2D. A similar proportion of DBT-only AD was represented by high-risk lesions
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