93 research outputs found
Comment on Ziebert & Aranson, “Modular approach for modeling cell motility”
No full textCommentary on the contribution by Falko Ziebert and Igor S. Aranson [1] in this special issue
Emergent conformational properties of end-tailored transversely propelling polymers
No full textWe study a model for a transversely propelling polymer whose end beads are driven differently from the polymer backbone, allowing to tailor-make polymer conformations and dynamics
Reply to comment on “Polymerization, bending, tension: What happens at the leading edge of motile cells?” by Falko Ziebert and Igor S. Aranson
No full textWe are grateful to Falko Ziebert and Igor Aranson, who continue with their comment on our publication [5] a discussion on modelling concepts. Ziebert and Aranson present in their contribution to this volume [14] a model concept for cell motility and morphodynamics focusing on gel flow and its determinants. This type of models is particularly useful for describing slow dynamics on the length scale of the whole cell and modelling of cell shape [1,8,11,13,14]. Our approach is set apart from the gel models by taking into account a weakly cross-linked F-actin network region close to the location of polymerization in the lamellipodia of motile cells (semi-flexible region) in addition to the gel in the bulk. This addition explains a variety of non-linear dynamic regimes in cellular and reconstituted systems, and the force-velocity relation of fish keratocytes. Ziebert and Aranson point out in their comment that 1) a more detailed modelling of gel processes may be required to capture large cell deformations, 2) the dynamics of adhesion strength and distribution may be relevant for understanding the relation between cell shape, the dynamic regime of motion and cell velocity, 3) coarse grained models may allow for unifying both concepts, and 4) fluctuations are important in morphodynamics
Liverpool and marchetti reply
No full textA Reply to the Comment by Falko Ziebert and Walter Zimmermann.</p
A camera trap survey of nocturnal mammals on former farmland in the eastern Free State Province, South Africa, 10 years after removing livestock
No full text<p>This archive contains the data and R scripts used for the following study:</p>
<p>Buschke, F.T.(unpublished). A camera trap survey of nocturnal mammals on former farmland in the eastern Free State Province, South Africa, 10 years after removing livestock</p>
<p>A written description of the research methodology can be obtained from the manuscript. Please consult the README.txt file for a detailed outline of all the files in this archive.</p>
<p>Any comments or inquiries can be directed to the author, Falko Buschke ([email protected])</p>
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Analysing the assemblage dispersion field
No full text<p>This archive contains the data and R scripts used for the following study:</p>
<p>Buschke, F.T., Brendonck, L. & Vanschoenwinkel (2015). Simple mechanistic models can partially explain local but not range-wide co-occurrence of African mammals. Global Ecology and Biogeography doi: 10.1111/geb.12316</p>
<p>Please be sure to read the README.txt file first, before attempting to use these data.</p>
<p>A written description of the research methodology can be obtained from the manuscript.</p>
<p>Any comments or inquiries can be directed to the lead author, Falko Buschke ([email protected])</p>
<p> </p
Modeling Pattern Formation in Biopolymer Systems induced by Reaction Kinetics and Molecular Motors
No full textCoarse-graining the vertex model and its response to shear
No full textTissue dynamics and collective cell motion are crucial biological processes.
Their biological machinery is mostly known, and simulation models such as the
"active vertex model" (AVM) exist and yield reasonable agreement with
experimental observations like tissue fluidization or fingering. However, a
good and well-founded continuum description for tissues remains to be
developed. In this work we derive a macroscopic description for a
two-dimensional cell monolayer by coarse-graining the vertex model through the
Poisson bracket approach. We obtain equations for cell density, velocity and
the cellular shape tensor. We then study the homogeneous steady states, their
stability (which coincides with thermodynamic stability), and especially their
behavior under an externally applied shear. Our results contribute to elucidate
the interplay between flow and cellular shape. The obtained macroscopic
equations present a good starting point for adding cell motion, morphogenetic
and other biologically relevant processes.Comment: 14 pages, 11 figure
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