6,239 research outputs found
On co-authorship for author disambiguation
No full textAuthor name disambiguation deals with clustering the same-name authors into different individuals. To attack the problem, many studies have employed a variety of disambiguation features such as coauthors, titles of papers/publications, topics of articles, emails/affiliations, etc. Among these, co-authorship is the most easily accessible and influential, since inter-person acquaintances represented by co-authorship could discriminate the identities of authors more clearly than other features. This study attempts to explore the net effects of co-authorship on author clustering in bibliographic data. First, to handle the shortage of explicit coauthors listed in known citations, a web-assisted technique of acquiring implicit coauthors of the target author to be disambiguated is proposed. Then, a coauthor disambiguation hypothesis that the identity of an author can be determined by his/her coauthors is examined and confirmed through a variety of author disambiguation experiments. (C) 2008 Elsevier Ltd. All rights reserved.X1174sciescopu
Corrigendum
No full textChen ZQ, Liu Y, Zhao JH, Wang L, Feng NP. Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system. International Journal of Nanomedicine. 2012;7:1115–1125.Figures 1 and 4 have been corrected.Read the original article
A morph-specific daily cycle in the rate of JH biosynthesis underlies a morph-specific daily cycle in the hemolymph JH titer in a wing-polymorphic cricket
Full text linkA previous study documented a high amplitude, morph-specific daily cycle in the hemolymph JH titer in the wing-polymorphic cricket, Gryllus firmus. The JH titer rose and fell 10–20 fold in the flight-capable [LW(f), long-winged] morph during the late-photophase- early scotophase, while it was relatively constant during that time in the flightless (SW, short-winged) morph. In the present study we documented a dramatic morph-specific daily cycle in the in vitro rate of juvenile hormone (JH) biosynthesis that was tightly correlated with the hemolymph JH titer on days 5–7 of adulthood. Biosynthetic rates rose and fell 1–2 fold between the late photophase-early scotophase on each of days 5–6 and 6–7 of adulthood in the LW(f) morph, while biosynthetic rates were relatively constant during this period in the flightless, short-winged morph (SW), except for a slight dip in the rate of biosynthesis late in the photophase on these days. Similar morph-specific patterns of JH biosynthesis were observed whether rates were measured on corpora allata attached to corpora cardiaca in males or females, or on corpora allata alone. Hemolymph juvenile hormone esterase activity was significantly higher in the LW(f) vs. the SW morph during the beginning of scotophase, when the JH titer is decreasing rapidly in the LW(f) morph. Results indicate that the morph-specific daily cycle in the JH titer in G. firmus is primarily regulated by a morph-specific daily cycle in the rate of JH biosynthesis and to a lesser degree by hemolymph JH esterase activity. This is the first documentation of a diurnal cycle in the rate of JH biosynthesis in any insect, or a daily cycle in the rate of JH biosynthesis that is correlated with a specific morph in a polymorphic species. Results have important implications for the endocrine regulation of dispersal polymorphism, circadian rhythms of insect hormone titers and their regulators, and general studies of the JH titer and its regulation in insects
Numerical investigation of dynamic soil response around a submerged rubble mound breakwater: II. Loose sandy seabed
No full textLow-crested structures such as submerged rubble mound breakwaters (RMB) are commonly used as successful examples of coastal protection measures. This study addresses foundation issues related to the performance of a submerged RMB constructed on a liquefiable site where the foundation soils have been loosely deposited; these issues were investigated using an integrated numerical model proposed by Zhao et al. (2018). Unlike previous work in Zhao et al. (2018), the dynamic features of loose sand deposits (i.e. build-up of pore water pressures, development of plastic strains, degradation of soil stiffness) due to the fluid–seabed-structure interactions, accompanied by the onset of liquefaction, were simulated. The reliability of this model to predict the liquefaction susceptibility of loose sand deposits was validated against the experimental results available in literature. This study shows that the submerged RMB constructed on a liquefiable seabed experienced progressive and asymmetric downward settlement under successive loading cycles. The opposing currents in the wave field tended to enhance this asymmetric settlement whereas the following currents did the opposite. Regardless of changes to the magnitude and direction of current velocities, ignoring the currents in the wave field may lead to an overestimation of the increased rate of residual pore water pressures in the region underneath the breakwater, particularly in shallow soil layers where the maximum relative differences can reach up to 120% ofNo Full Tex
The distance-regular graphs such that all of its second largest local eigenvalues are at most one
No full textIn this paper, we classify distance-regular graphs such that all of its second largest local eigenvalues are at most one. Also we discuss the consequences for the smallest eigenvalue of a distance-regular graph. These extend a result by the first author, who classified the distance-regular graphs with smallest eigenvalue -1 - b(1)/2. (C) 2011 Elsevier Inc. All rights reserved.X1154sciescopu
Geochronology and geochemistry of the c. 80 Ma Rutog granitic pluton, northwestern Tibet: implications for the tectonic evolution of the Lhasa Terrane
No full textThe hemolymph JH titer exhibits a large-amplitude, morph-dependent, diurnal cycle in the wing-polymorphic cricket, \u3ci\u3eGryllus firmus\u3c/i\u3e
Full text linkThe hemolymph juvenile hormone (JH) titer was measured in over 500 flight-capable and flightless, adult female Gryllus firmus at 3–6 h intervals during each of days 2–8 of adulthood. The flight-capable morph exhibited a large-amplitude daily cycle in the hemolymph JH titer, while the flightless morph exhibited a barely perceptible cycle. The JH titer cycle was observed on all days in the flight-capable morph, but the large amplitude cycle (\u3e15–20 fold increase in mean titer; \u3e100-fold increase in some individuals), began on day 5. For both the large and small amplitude cycles, the JH titer peaked near the end of the photophase–beginning of the scotophase. The hemolymph ecdysteroid titer did not exhibit a corresponding large amplitude daily cycle, although a low amplitude cycle (1–3-fold change) was seen in both morphs. The large magnitude rise in the JH titer in the flight-capable morph during the photophase was not due to decreased hemolymph volume or JH degradation. Daily cycles in the JH titer may be common, but may have gone unnoticed in other insect species due to restricted temporal sampling. Failure to identify these cycles can result in substantial errors in inferring biological roles for JH. Because JH regulates flight behaviors, morph-specific daily cycles in the JH titer may be especially common in dispersal-polymorphic insects, in which flight is restricted to one morph during a limited period of the day or night. However, because JH regulates numerous biological traits, analogous cycles may be common in insects exhibiting other types of complex (e.g. caste or phase) polymorphism, in which morphs differ in a biological characteristic that is restricted to a specific period of the photophase or scotophase
Morph-associated JH titer diel rhythm in \u3ci\u3eGryllus firmus\u3c/i\u3e: Experimental verification of its circadian basis and cycle characterization in artificially selected lines raised in the field
Full text linkPrevious studies demonstrated a high-amplitude, diel cycle for the hemolymph JH titer in the wing-polymorphic cricket, Gryllus firmus. The JH titer rose and fell in the flight-capable morph (long-winged, LW(f)) above and below the relatively temporally invariant JH titer in the flightless (short-winged, SW) morph. The morph-specific JH titer cycle appeared to be primarily driven by a morph-specific diel cycle in the rate of JH biosynthesis. In the present study, cycles of the JH titer and rate of JH biosynthesis in the LW(f) morph persisted in the laboratory under constant darkness with an approximate 24 h periodicity. The JH titer cycle also shifted in concert with a shift in the onset of the scotophase, was temperature compensated in constant darkness, and became arrhythmic under constant light. These results provide strong support for the circadian basis of the morph-specific diel rhythm of the JH titer and JH biosynthetic rate. Persistence of the JH titer cycle under constant darkness in multiple LW-selected and SW-selected stocks also provides support for the genetic basis of the morph-associated circadian rhythm. The morph-specific JH titer cycle was observed in these stocks raised in the field, in both males and females, in each of 3 years studied. The onset of the cycle in the LW(f) morph, a few hours before sunset, correlated well with the onset of the cycle, a few hours before lights-off, in the laboratory. The morph-specific JH titer cycle is a general feature of G. firmus, under a variety of environmental conditions, and is not an artifact of specific laboratory conditions or specific genetic stocks. It is a powerful experimental model to investigate the mechanisms underlying endocrine circadian rhythms, their evolution, and their impact on life history evolution
Molecular Dynamics Simulations to Investigate the Structural Stability and Aggregation Behavior of the GGVVIA Oligomers Derived from Amyloid beta Peptide
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