1,721,231 research outputs found
Re: Marlon Perera, Nathan Papa, Daniel Christidis, et al. Sensitivity, Specificity, and Predictors of Positive 68Ga-Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer: A Systematic Review and Meta-analysis. Eur Urol 2016;70:926-37
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Medical treatment of LUTS/BPH
No full textSeveral drug therapies are available for male patients with bothersome lower urinary tract symptoms. Monotherapy with α-blockers is a commonly used and effective treatment to quickly improve LUTS, quality of life, and Q max. The main differences among the drugs are in the profile of adverse events [AEs], with cardiovascular AEs less prevalent with uroselective drugs (and especially with the novel silodosin, which is the compound with the highest selectivity). Conversely, ejaculatory dysfunction is less prevalent with nonselective drugs. 5α-reductase inhibitors [5-ARIs], alone or in combination with α-blockers, might be offered to men who have moderate to severe LUTS and an enlarged prostate to reduce the risk of urinary retention and prostate-related surgery. Those patients with prevalent storage LUTS may have benefited from anticholinergics. The risk of urinary retention with that category of drugs is minimal if patients with a higher risk of bladder outlet obstruction are avoided (e.g., those with PVR >200 mL, Q max <5 mL/s, or history of prior retention). Finally, tadalafil 5 mg is effective in improving symptoms in patients with LUTS, with or without concomitant erectile dysfunction
Surgical management of localized prostate cancer
No full textThe surgical management of localized prostate cancer continues to evolve. Since the initial report by Walsh and Donker on the principles of the anatomical radical prostatectomy, further refinements in technique improved intra-operative outcomes including blood loss and transfusion rates; as well as post-operative complications including incontinence and impotence. A better understanding of the impact of positive margins on cancer control allow the surgeon to modify the procedure to minimize this occurrence. Robotic surgery represents the next step in the evolution of conventional laparoscopic surgery, including all of the advantages of the traditional laparoscopic approach with the addition of decreasing the learning curve and improving the quality of the surgical technique. RALP has allowed urologists who were traditionally trained in open retropubic surgery to move into the field of minimally invasive surgery. Market demand for high-tech surgery and new technologies also has been an important driver of RALP. © 2013 by Nova Science Publishers, Inc. All rights reserved
EVALUATION OF THE PROGNOSTIC IMPACT OF 18F-CHOLINE PET/CT IN PATIENTS WITH SKELETAL RECURRENCE PROSTATE CANCER
No full textPosterior muscolofascial reconstruction incorporated into urethrovescical anastomosis during robot-assisted radical prostatectomy
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