187,334 research outputs found
Lifestyle approach against obesity in menopause: role of the new short questionnaire to assess adherence to the Mediterranean Diet andnutritional sustainability MedQ-Sus
No full textINTRODUCTION: The changing hormonal milieu in post-menopausal women (PMW) predisposes them to increase cardiovascular (CV) risk, due to a constellation of risk factors, suchas visceral obesity, atherogenic dyslipidaemia and arterial hypertension. Our ongoing study aims to evaluate the impact of dietary changes in CV risk in PMW by means of a newMediterranean Diet (MD) adherence questionnaire "MedQ-Sus" (1) which excludes alcohol consumption and introduces a sustainability score.
METHODS: For 1 year, 65 PMW with BMI 24-39 Kg/m2 and at least another CV risk factor were followed-up (FU) each 3 months. Anthropometric parameters and blood pressure weretaken. Questionnaires on medical history, lifestyles, food frequency (FFQ) and adherence to MD such as MEDAS and MedQ-Sus were administered. Balanced low-calorie dietary planwith quantitative advice were released. Repeated measures ANOVA at 1 year were performed
RESULTS: We observed at 1 year a significant increase (p195 g/day from 33.9% to 52.3%) and fresh fruit (>300 g/day from 24.6 to 26.2%) and reduction in consumption of dairy products (<180 g/dayfrom 10.8% to 18.4%). No change was observed with MEDAS questionnaire due to the significant reduction in the consumption of wine (≥7 glasses/week from 21.5% to 10.8%) andsautéed (≥ 2 times/week from 40% to 29.2%). One-year sustainability score assessed with MedQ-Sus was significantly increased (from 4 to 4.9 points; p<0.05). If we considered tertilesof MedQ-Sus score at baseline (Fig. 1), the MD adherence significantly increased at 1 year in the first and second tertiles while stable in the third. Those changes were mainly due to adecreased consumption of animal proteins (Δ= -5.3%) and an increased consumption of plant protein (Δ= +5.3%), reduction in fats consumption of animal origin (Δ= -8.4 g/day) and inparticular of saturated fatty acids (Δ= -5.0%). We observed at 1 year significant reductions (p<0.01) in weight (Δ=-4.3 Kg), BMI (Δ=-1.6 Kg/m2), waist (Δ=-4.1cm) and hips (Δ=-3.0cm)circumferences, subscapular (Δ=-5.2mm), suprailiac (Δ=-2.9mm) and triceps (Δ=-4.5mm) skinfolds, adipose area of the arm (AFA) (Δ=-6.4cm2) and fat mass (Δ=-4.2kg) withoutvariation of the lean mass (Δ=-0.2 kg, p=0.48). All those reductions were followed by change in the obesity prevalence (-21.1%), in the fat mass distribution with 10% reduction inabdominal and truncular obesity, and in systolic (Δ=-7.4mmHg) and diastolic (Δ=-3.6mmHg) BP (Fig 2).
CONCLUSIONS: The study underlines the medium-term utility of a 1 year balanced low-calorie diet in PMW with elevated CV risk factors. Furthermore, the new MedQ-Susquestionnaire is effective in evaluating and monitoring adherence to MD and the sustainability of DM, allowing a better counseling in menopausal women.
1) Ruggeri S et al. New Validated Short Questionnaire for the Evaluation of the Adherence of Mediterranean Diet and Nutritional Sustainability in All Adult Population Groups. Nutrients2022, 14, 5177
matthew-p-brown/E_cells_2023: E_cells_2024
No full text<p>This page contains the code used to analyze behavior and voltage imaging data from <strong>Brown et al., 2024</strong>. Further questions can be sent to the corresponding author, Dr. Mark N. Wu ([email protected]).</p>
REDUCTION OF URIC ACID LEVELS IN A DIETARY INTERVENTION STUDY IN POST-MENOPAUSE WOMEN WITH A CARDIOVASCULAR RISK FACTOR
No full textBACKGROUND: Serum uric acid (SUA) levels in women remain low until menopause, when SUA levels begin to increase and reach levels similar to those found in men due to the loss of the uricosuric effect of estrogen. During menopause, other factors influence SUA levels such as hormone replacement therapy which reduces them and dietary factors which increase levels (meat, seafood, fructose, alcohol and sodium) or decrease them (coffee and ascorbic acid). In particular, the Mediterranean diet can reduce SUA levels in patients with asymptomatic hyperuricemia.
AIM: To evaluate the impact of dietary changes on SUA levels in post-menopausal women free from hormone replacement therapy in a dietary intervention study.
METHODS. Postmenopausal women with a BMI between 24 and 39 kg/m2 and at least one additional cardiovascular (CV) risk factor followed for two years with a quarterly follow-up. Anthropometric measurements were carried out including waist and hip circumferences, waist-hip ratio and skin fold measurement, blood pressure measurement in triplicate and assessment of body composition using bioimpedance measurement; Questionnaires on medical history, physical activity and food frequency (FFQ) were administered. Participants were placed on a balanced, low-calorie diet designed to meet their specific needs and goals. Biochemical tests at baseline and follow-up included uric acid, cholesterol, triglycerides, glucose, and insulin. Repeated measures ANOVA were performed at the end of the one-year period to analyze changes in anthropometric measurements, BP, biochemical parameters, and other variables.
RESULTS. At one-year, significant reductions (p<0.01) in weight (-4.3 kg), BMI, waist circumferences (-4.1 cm), subscapular (-5.2 mm), suprailiac (- 2.9 mm) and triceps (-4.5 mm), of the fat mass obtained by skinfold measurement (-4.2 kg) without reduction in lean mass (-0.2 kg), systolic (-7.4 mmHg) and diastolic (-3.6 mmHg) BP associated with a reduction in uric acid levels (0.38 mg/dl).
CONCLUSIONS: The study highlights the importance of dietary interventions in menopausal women in managing SUA levels and related health risks
Dr. Edward P. Wimberly, ITC, July 2011
No full textThis video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer
Riprap Stability Model Tests
No full textI. Introduction and Background 11. Test Setup and Conditions 111. Presentation of Data IV. Results V. Conclusions Appendices 1. Definition of Terms 2. Photographs of Model Dike Section 3. Model Riprap Stone Analysis 4. Tables of Expected Percent Damage for Armor Stone with Unit WeightsKWP-collectio
Laparoscopy for colectomy accelerates restoration of bowel function when using patient controlled analgesia
No full textPurpose: A standardized care plan incorporating patient-controlled analgesia with iv morphine and a non-accelerated feeding schedule following colectomy was used to compare return of bowel function and hospital discharge times following surgery done by laparoscopy or laparotomy. Methods: Thirty-eight patients were assigned to undergo either laparoscopic or laparotomy colon resection. Postoperative analgesia was achieved with patient-controlled analgesia with iv morphine. General anesthesia and perioperative care were standardized, and a traditional surgical and nursing care program was implemented. Gastrointestinal function (time from surgery to return of passage of flatus and presence of bowel movements), pain intensity (visual analogue scale) at rest, on coughing and on mobilization, amount of morphine used, and criteria for discharge and length of hospital stay were recorded. Results: Bowel movements resumed earlier in the laparoscopic group (P < 0.05), but not passage of flatus. No significant relationship was found between the amount of morphine used and return of bowel function. Cumulative morphine consumption during the first two postoperative days was similar in both groups. Where a trend towards lower postoperative visual analogue scale scores was observed in the laparoscopic group, visual analogue scale scores on coughing were lower in the laparoscopic vs laparotomy group only during the first 24 hr (P < 0.05). Length of hospital stay was significantly shorter in the laparoscopic group (P < 0.05), although times to meet discharge criteria were similar in both groups. Conclusions: When patient-controlled analgesia with morphine and a traditional perioperative program are used, a laparoscopic approach to colon surgery promotes earlier restoration of bowel function and more rapid hospital discharge in comparison to resection by laparotomy
Lipschitz free p-spaces for 0 < p < 1
No full textThis paper initiates the study of the structure of a new class of p-Banach spaces, 0 <p < 1, namely the Lipschitz free p-spaces (alternatively called Arens—Eells p-spaces) Fp(M) over p-metric spaces. We systematically develop the theory and show that some results hold as in the case of p = 1, while some new interesting phenomena appear in the case 0 <p < 1 which have no analogue in the classical setting. For the former, we, e.g., show that the Lipschitz free p-space over a separable ultrametric space is isomorphic to ℓp for all 0 <p ≤ 1. On the other hand, solving a problem by the first author and N. Kalton, there are metric spaces N⊂M such that the natural embedding from Fp(N) to Fp(M) is not an isometry.F. Albiac acknowledges the support of the Spanish Ministry for Economy and Competitivity Grants MTM2014-53009-P for Análisis Vectorial, Multilineal y Aplicaciones, and MTM2016-76808-P for Operators, lattices, and structure of Banach spaces as well as the Spanish Ministry for Science and Innovation under Grant PID2019-1077701GB-I00. J. L. Ansorena acknowledges the support of the Spanish Ministry for Economy and Competitivity Grant MTM2014-53009-P for Análisis Vectorial, Multilineal y Aplicaciones. M. Cúth has been supported by Charles University Research program No. UNCE/SCI/023 and by the Research grant GACR 17-04197Y. M. Doucha was supported by the GACR project 16-34860L and RVO: 67985840
Linkage disequilibrium and within-breed genetic diversity in Iranian Zandi sheep
No full textThis research aimed to measure the extent of linkage disequilibrium (LD), effective population size (Ne), and runs of homozygosity (ROHs) in one of the major Iranian sheep breeds (Zandi) using 96 samples genotyped with Illumina Ovine SNP50 BeadChip. The amount of LD (r2) for single-nucleotide polymorphism (SNP) pairs in short distances (10-20 kb) was 0:21±0:25 but rapidly decreased to 0:10±0:16 by increasing the distance between SNP pairs (40-60 kb). The Ne of Zandi sheep in past (approximately 3500 generations ago) and recent (five generations ago) populations was estimated to be 6475 and 122, respectively. The ROH-based inbreeding was 0.023. We found 558 ROH regions, of which 37% were relatively long (<10 Mb). Compared with the rate of LD reduction in other species (e.g., cattle and pigs), in Zandi, it was reduced more rapidly by increasing the distance between SNP pairs. According to the LD pattern and high genetic diversity of Zandi sheep, we need to use an SNP panel with a higher density than Illumina Ovine SNP50 BeadChip for genomic selection and genome-wide association studies in this breed
John P. MacLean portrait
No full textPhotograph of Ohio author John P. MacLean (1848-1939). MacLean was born in Franklin, Ohio, and is remembered as a Universalist minister, historian and archaeologist. In addition to writings on Scottish history and the Shakers, his work included the books "A Manual of the Antiquity of Man" (1877), "The Mound Builders" (1879) and "Mastodon, Mammoth and Man" (1880)
John P. MacLean portrait
No full textPhotograph of Ohio author John P. MacLean (1848-1939). MacLean was born in Franklin, Ohio, and is remembered as a Universalist minister, historian and archaeologist. In addition to writings on Scottish history and the Shakers, his work included the books "A Manual of the Antiquity of Man" (1877), "The Mound Builders" (1879) and "Mastodon, Mammoth and Man" (1880)
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