1,721,044 research outputs found
Tracheal resection and reconstruction for malignant disease
No full textMalignant tracheal neoplasms are rare diseases, mostly represented by squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC). Symptoms presentation is often misleading and diagnosis may be delayed for months or years, so clinical suspicion plays a fundamental role. Corner stones in the diagnostic pathway are represented by rigid endoscopy and computed tomography (CT) scan, necessary to correctly stage the patients and identify the optimal surgical candidate. When appropriate, surgical resection and reconstruction is still the best opportunity to achieve a long-term survival with a good quality of life, but this kind of surgery is always a very challenging procedure and a wide experience with an in-depth knowledge of every technical detail, from selection of patient, to choice of surgical approach to reconstruction techniques, are needed and recommended
PCaDA statement of methods
Full text linkThis paper describes the methods for the numerical simulation of pantograph-catenary interaction developed at Politecnico di Milano and implemented in the simulation software PCaDA (Pantograph-Catenary Dynamic Analysis). The paper also describes how these methods were applied in the pantograph-catenary interaction benchmark treated in this special issue and provides some evaluation of the results obtained using PCaDA in this benchmark
Reconstructive tracheo-bronchial surgery: bronchial, tracheal and vascular sleeve resections
No full textBackground. Tracheo-bronchial and vascular sleeve procedures represent an effective surgical therapy for benign lesions, tumours of low-grade malignancy and bronchogenic carcinoma in selected patients.
Methods. From January 1980 to August 2002, 248 patients underwent sleeve procedures. We performed 195 bronchial sleeves and 53 tracheo-bronchial sleeves: 39 cases of sleeve lobectomy (SL) had vascular plasty associated, five of whom were arterial sleeve resection. Histological examination revealed 178 squamous carcinomas, 24 adenocarcinomas, 5 small cells carcinomas, 5 large cell carcinomas, 1 adenosquamous carcinomas, 25 bronchial carcinoids (19 typical and 6 atypical), 4 mucoepidermoid tumours, 4 adenoid-cystic carcinoma, 1 metastatic tumours, 1 bronchial stenosis post lung transplantation. 123 patients had N0 disease, 75 had N1 disease and 50 patients had N2 disease. In bronchial carcinoid disease 5 patients had N+. 106 patients had preoperative and/or postoperative irradiation/CT; 14 patients with carcinoid tumours underwent preoperative LASER-therapy. In 125 patients we used a perianastomotic pedicled flap.
Results. 48 patients (19.3%) had postoperative complications. The 30-day mortality was 6% (15 patients). Overall survival at 5 and 10 years for all patients with lung cancer was 42% and 31%, respectively. Low malignancy and carcinoid tumours had overall survival of 88% at 5 and 10 years.
Conclusions. Bronchovascular procedures are a safe and effective therapy in selected patients with pulmonary neoplasia. Tracheo-bronchial sleeves are associated with high postoperative mortality and complication rates. A multivariate analysis showed that nodal status, age, preoperative RT and histology were the significant prognostic factors affecting the long-term survival (P<0,05)
Clamshell approach for lung harvest in donor with previous aortic valve substitution
No full textIn this report we present a successful clamshell approach for lung harvest, with subsequent two single lung transplantations in two different patients, from a donor who had previous median sternotomy for aortic valve substitution
Stockbridge-type damper effectiveness evaluation: part II - The influence of the impedance matrix terms on the energy dissipated
No full textDispositivo per prove di rendimento e fatica su viti a ricircolo di sfere
No full textIl dispositivo progettato permette di realizzare prove a fatica sulle trasmissioni meccaniche a viti a ricircolo di sfere e di valutare contestualmente il rendimento meccanico della trasmissione e lo stato di usura della stessa.
Tale dispositivo sfrutta il ricircolo di potenza, ottenuto precaricando, attraverso delle molle a tazza, due chiocciole montate su un unica vite. Tale accorgimento permette di ridurre la potenza meccanica che deve essere introdotta nel dispositivo per realizzare le prove a fatica e nello stesso tempo riduce i carichi che si scaricano sui supporti della vite.
Un opportuno sistema di misura acquisisce il valore della forza di precarico esercitata dalle molle a tazza, le forze scaricate a terra (reazioni vincolari) e la distanza fra le due chiocciole. Attraverso questi dati è possibile valutare il rendimento della trasmissione e il suo stato di usura
Complex lobectomy in a patient with lung cancer and pulmonary artery sling
No full textPulmonary artery sling is a rare congenital anomaly of the origin and course of the left pulmonary artery. This condition typically presents with respiratory failure in young infancy, while asymptomatic cases are uncommon. We describe the case of an adult patient with a lung adenocarcinoma of the right upper lobe, extending into the hilum and superior mediastinum, and with a previously unknown pulmonary artery sling anomaly. The local invasiveness of the tumor and the peculiar vascular anatomy contributed to a unique surgical scenario, wherein multiple reconstructive procedures were required
- …
