208,544 research outputs found

    Jia ru ju he wu dui jun yun tuan liu ji jun yun tuan liu dui liu de ying xiang

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    Wong, Chai Kwok = 加入聚合物對均勻湍流及均勻湍流對流的影響 / 黃濟國.Thesis M.Phil. Chinese University of Hong Kong 2013.Includes bibliographical references (leaves 89-91).Abstracts also in Chinese.Title from PDF title page (viewed on 01, November, 2016).Wong, Chai Kwok = Jia ru ju he wu dui jun yun tuan liu ji jun yun tuan liu dui liu de ying xiang / Huang Jiguo

    Comrade Chen Yun

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    Chinese propaganda poster. Color poster. Translation: Comrade Chen Yun. c.1970s.https://digitalcommons.whitworth.edu/chinese_art_posters/1032/thumbnail.jp

    Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12R beta(2) or IL-18R alpha

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    The oncolytic adenovirus (Ad) is currently being advanced as a promising antitumor remedy as it selectively replicates in tumor cells and can transfer and amplify therapeutic genes. Interleukin (IL)-12 induces a potent antitumor effect by promoting natural killer (NK) cell and cytotoxic T cell activities. IL-18 also augments cytotoxicity of NK cells and proliferation of T cells. This effect further enhances the function of IL-12 in a synergistic manner. Therefore, we investigated for the first time an effective cancer immunogene therapy of syngeneic tumors via intratumoral administration of oncolytic Ad co-expressing IL-12 and IL-18, RdB/IL-12/IL-18. Intratumoral administration of RdB/IL-12/IL-18 improved antitumor effects, as well as increased survival, in B16-F10 murine melanoma model. The ratio of T-helper type 1/2 cytokine as well as the levels of IL-12, IL-18, interferon-gamma and granulocyte-macrophage colony-stimulating factor was markedly elevated in RdB/IL-12/IL-18-treated tumors. Mice injected with RdB/IL-12/IL-18 also showed enhanced cytotoxicity of tumor-specific immune cells. Consistent with these results, immense necrosis and infiltration of NK cells, as well as CD4(+) and CD8(+) T cells, were observed in RdB/IL-12/IL-18-treated tumor tissues. Importantly, tumors treated with RdB/IL-12/IL-18 showed an elevated number of T cells expressing IL-12R beta 2 or IL-18R alpha. These results provide a new insight into therapeutic mechanisms of IL-12 plus IL-18 and provide a potential clinical cancer immunotherapeutic agent for improved antitumor immunity.This work was supported by grants from the Ministry of Knowledge Economy (10030051, Dr C-O Yun), the Korea Science and Engineering Foundation (R15-2004-024-02001-0, 2009K001644, 2010-0029220, Dr C-O Yun), the Korea Food and Drug Administration (KFDA-10172-332 to Dr C-O Yun), and Yonsei University College of Medicine faculty research grant (6-2010-0052, Dr C-O Yun). I-K Choi is a graduate student sponsored by KOSEF through National Core Research Center for Nanomedical Technology. J-S Lee and S-N Zhang are graduate students sponsored by the Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

    Yun Wei, Piano

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    2018, February 2 Yun Wei, piano, performed Schubert: Sonata No. 19 in C minor, D. 958; Brahms: Sonata No. 3 in F minor, Op. 5https://digitalcommons.rockefeller.edu/tri-institutional-noon-recitals/1079/thumbnail.jp

    OsMADS16 genetically interacts with OsMADS3 and OsMADS58 in specifying floral patterning in rice

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    Rice (Oryza sativa) has unique floral patterns that contribute to grain yield. However, the molecular mechanism underlying the specification of floral organ identities in rice, particularly the interaction among floral homeotic genes, remains poorly understood. Here, we show that the floral homeotic gene OsMADS16 (also called SUPERWOMAN1, SPW1, a B-class gene) acts together with the rice C-class genes OsMADS3 and OsMADS58 in specifying floral organ patterning. OsMADS16 and the two C-class genes have an overlapping expression pattern in the third whorl founder cells. Compared with the single mutants, both spw1-1 osmads3-4 and spw1-1 osmads58 double mutants exhibit additional whorls of glume-like organs within the flower, particularly an extra whorl of six glume-like structures formed at the position of the wild-type stamens. These ectopic glume-like structures were shown to have palea identity through cellular observation and in situ hybridization analysis using marker genes. Our results suggest that B- and C-class genes play a key role in suppressing indeterminate growth within the floral meristem, particularly whorl-3 primordia. We also hypothesize that, in contrast to previous assumptions, the specialized spikelet organ in rice, the palea, is the counterpart of the sepal in eudicots, and the lemma is homologous to the bract.Dapeng Yun, Wanqi Liang, Ludovico Dreni, Changsong Yin, Zhigang Zhou, Martin M. Kater Dabing Zhan

    Yun Dongju and the Effects of Colonization on Literature

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    Tucked away in a small room, in a country he used to recognize, poet Yun Dongju (1917-1945) drafted nineteen poems that would become the foundation of his legacy: Sky, Wind, Stars, and Poetry. Growing up during the Japanese annexation of Korea, Yun drafted his poetry during a time where Korean language and cultural practices were banned by Imperial Japan. In my essay, I will use Yun’s poetry as a viewpoint for dissecting the negative effects of literary censorship brought about by colonization. Additionally, I will discuss the significance of how Yun – one of Korea’s most famous poets – uses poetry to help readers understand the national trauma caused by Japan’s colonial rule and how it affected (and still affects) the morale and mindset of Korean people born and raised during the occupation (1915-1945). In 1942, after finishing his first anthology of poetry, Yun Dongju packed his bags and moved to study at Rikkyo University in Tokyo, Japan. During this time, he wrote his final poem, “Swipge Ssuieojin Si” (A Poem That Came Easily). In his poem, Yun writes, “The night rain whispers outside the window / of my six-mat room, in an alien country. The poet has a sad vocation, I know; should I write another line of poetry?” (McCann 94-95). Aware of the position he is in, Yun questions if the poetry he is writing is worth the risk he is taking. The six-mat room is in reference to a tatami mat, an architectural piece common in Japanese households. Additionally, the “night rain” he refers to – originally written in Korean as 밤비 or bambi – is a common way Korean people refer to the Japanese occupation (Kim).  Yun continues with his reflection of home as he writes, “Having received my tuition from home in an envelope / soaked with the smell of sweat and love,” (McCann 94-95). Through analyzing Yun’s poetry and historical analyses, I plan to examine what Jinhee Kim argues as Yun’s philosophy: “poets must write poems to shed light during such dark times” (208), as well as how the Japanese empire – according to Yasuko Claremont – showed “how powerful control by the state can be, reducing its citizens to compliant units,” (137), to help readers gain a new respect for survivors of colonialism in Korea and the importance of literature and self-expression in times of political unrest. Additionally, I will discuss why Yun’s personal experiences as a Korean living in Japan are integral to understanding the gravity of Japan\u27s occupation, and the consequences of an empire seeking to oppress its occupants of all ages. Works Cited Kim, Min. Interview. Conducted by Author. September 7th, 2025. McCann, David. The Columbia Anthology of Modern Korean Poetry. New York: Columbia University Press, 2004. Claremont, Yasuko.“Young Poets Under the Shadow of War: Yun Dong-ju and Tachihara Michizō.” In “History Wars” and Reconciliation in Japan and Korea, edited by Michael Lewis, 125-141. New York: Palgrave Macmillan, 2017. Kim, Jinhee. “The Understanding of Yun Dong-ju in Three East Asian Countries.” Korea Journal, vol. 52, no. 3, 2012, pp. 201-225

    Optimization of the Thermoelectric Figure of Merit in Crystalline C₆₀ with Intercalation Chemistry

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    Crystalline C₆₀ is an appealing candidate material for thermoelectric (TE) applications due to its extremely low thermal conductivity and potentially high electrical conductivity with metal atom intercalation. We investigate the TE properties of crystalline C₆₀ intercalated with alkali and alkaline earth metals using both classical and quantum mechanical calculations. For the electronic structure, our results show that variation of intercalated metal atoms has a large impact on energy dispersions, which leads to broad tunability of the power factor. For the thermal transport, we show that dopants introduce strong phonon scattering into crystalline C₆₀, leading to considerably lower thermal conductivity. Taking both into account, our calculations suggest that appropriate choice of metal atom intercalation in crystalline C₆₀ could yield figures of merit near 1 at room temperature

    Generation of Transgenic Mice Harboring Human Pulmonary Surfactant-related Protein B/C Genes

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    3 摘要 本研究主旨在探討小鼠原核胚經雙基因共同注射後,於體外培養至二細 胞時期再進行胚移置對產製攜帶雙基因轉殖小鼠效率之影響。轉殖基因之構築 係以乳腺專一表現之牛74 英文摘要 Generation of Transgenic Mice Harboring Human Pulmonary Surfactant-related Protein B/C Genes Yun-Yi Ma Abstract The purpose of this study was to investigate the effect of advanced culture to two-cell stage prior to co-injected mouse eggs on pups born and transgene integration efficiency by pronuclear gene microinjection. Transgenes were constructed by using a mature surfactant protein B (mSP-B) and C (mSP-C) cDNA fragment equipped with bovin

    FIGURE 1. Melampyrum koreanum K.-J. Kim & S.-M. Yun. A. Flowering branches. B. Upper corolla lobes and stamens. C. Developing flowers. D. Mature flower. E. Calyx and style. F. Lower leaf. G–H. Upper bract-like leaves. I–J. Capsules. K. Seeds. All scale bars are 1 in A new species of Melampyrum (Orobanchaceae) from Southern Korea

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    FIGURE 1. Melampyrum koreanum K.-J. Kim & S.-M. Yun. A. Flowering branches. B. Upper corolla lobes and stamens. C. Developing flowers. D. Mature flower. E. Calyx and style. F. Lower leaf. G–H. Upper bract-like leaves. I–J. Capsules. K. Seeds. All scale bars are 1 cm. Drawn from the holotype K.-J. Kim and Seok Min Yun 2008-1561(KUS).Published as part of Kim, Ki-Joong & Yun, Seok-Min, 2012, A new species of Melampyrum (Orobanchaceae) from Southern Korea, pp. 48-50 in Phytotaxa 42 on page 49, DOI: 10.11646/phytotaxa.42.1.6, http://zenodo.org/record/489483
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