79 research outputs found
The efficacy of curcumin on PDGF expression and NF-kappa B pathway: TNBS induced colitis
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Prediction Model for Complex Diverticulitis and Comparison of Outcomes for Diverticulitis in Turkish Versus American Patients Who Underwent Elective Surgery
No full textBackground: Diverticulitis is separated into complicated and uncomplicated, based on the patient’s presentation at the time of their initial attack of acute diverticulitis. The aim of this study was to identify risk factors for persistent complex diverticulitis, defined as an abscess, fistula, or stricture, at the time of elective surgery, and characterize outcomes in this patient population.
Method: This was a retrospective review of the 2010–2016 in the American College of Surgeons National Surgical Quality Improvement Project database. Individuals diagnosed with diverticulitis who underwent elective surgery were included. 1502 patients underwent elective surgery for diverticulitis, of which 559 (37%) patients had a surgical indication of persistent complex diverticulitis. We performed logistic regression analysis to identify risk factors for complex diverticulitis and evaluated a new prediction model.
Results:
The patients with complex diverticulitis were older (p <0.001), had worse functional status (p <0.001), more comorbidities (diabetes and hypertension), and a higher Charlson comorbidity index (2.7 vs. 1.6, p<0.001). They were more likely to have a history of tobacco or alcohol use (p <0.001), and be malnourished. Interestingly, patients found to have persistent complex diverticulitis did not have more episodes than uncomplicated patients (p=0.67). Surgical time was longer in complex diverticulitis and they were more likely to require diverting stomas and concurrent resections of adjacent structures. The area under curve from the test set was (0.75, 95%confidence interval 0.72-0.78), sensitivity and specificity were 0.890 (95% confidence interval;0.870-0.891) and 0.450 (95% confidence interval; 0.410-0.490), respectively.
Conclusions:
Patients undergoing elective surgery for complex diverticulitis did not have more episodes. Instead, complex diverticulitis may be a reflection of a complicated patient, suggesting that complicated patients should have a different algorithm of care at the time of their initial presentation with diverticulitis to prevent development of complex disease.Master’s Program in Clinical Investigatio
Correction to:Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY) (International Journal of Colorectal Disease, (2025), 40, 1, (194), 10.1007/s00384-025-04921-x)
No full textThe collaborative Author names are missing in the published proof. The Supplementary material is updated with 2 additional names in the collaborative Author’s list. Ali Yalcinkaya, Ahmet Yalcinkaya, Sezai Leventoglu, Bengi Balci, Alp Ozgun Borcek, Elif Ozeller, Ece Ozturk, Gulsum Sueda Kayacan, Berkay Enes Karaca, Ahmet Faruk Oyanik, Omer Faruk Gul, Basak Bolukbasi, Huseyin Gobut, Cagri Buyukkasap, Aydin Yavuz, Dara Aydin, Zeynep Akdagcik, Alina Pataeva, Douigou Hasan, Omar Hussein, Arda Ozgur Ozturk, Cem Arda Elumar, Ali Derman Dere, Asra Zeynep Balci, Rasim Ozturk, Yasar Copelci, Murat Kartal, Serkan Tayar, Mustafa Yeni, Tolga Kalayci, Ramazan Yavuz, Bulent Calik, Semra Demirli Atici, Selen Ozturk, Gizem Kilinc, Korhan Tuncer, Cengiz Aydin, Mustafa Yener Uzunoglu, Alp Yildiz, Aybala Yildiz, Can Sahin, Mehmet Caglikulekci, Elbrus Zarbaliyev, Murat Sevmis, Baris Sevinc, Nurullah Damburaci, Omer Karahan, Ozgen Isik, Said Kural, Xhenet Hysejni, Ahmet Aktas, Baris Yildiz, Gultekin Ozan Kucuk, Ahmet Can Sari, Mert Candan, Mehmet Mahir Ozmen, Cem Emir Guldogan, Emre Gundogdu, Munevver Moran, Mevlut Recep Pekcici, Saygin Altiner, Enes Cebeci, Tugba Yigit, Bedri Burak Sucu, Mert Col, Omer Faruk, Ozkan Hanife, Seyda Ulgur, Murat Kalin, Emre Furkan Kirkan, Abdullah Yildiz, Sema Yukseksag, Cagri Buyukkasap, Erdinc Kamer, Mesut Ozogul, Nihan Acar, Melek Gokova Bekler, Arif Atay, Halis Bag, Server Sezgin Uludag, Ahmet Necati Sanli, Sefa Ergun, Ergin Erginoz, Veysi Basbayandur, Mehmet Faik Ozcelik, Ahmet Askar, Yuksel Altinel, Adnan Hacim, Serhat Meric, Merve Tokocin, Talar Aktokmakyan, Yunus Aktimur, Kamil Ozdogan, Fikret Calikoglu, Tugba Koc Calikoglu, Ahmet Barcin, Ahmed Salhat, Guray Durmaz, Volkan Ozben, Erman Aytac, Zumrud Aliyeva, Arda Ulas Mutlu, Mert Tanal, Mustafa Fevzi Celayir, Aydin Eray, Tufan Ali Yuksel, Elif Baran, Banu Yigit, Erhan Eroz, Aykhan Abbasov, Hakan Yanar, Huseyin Onur Aydin, Murathan Erkent, Tugan Tezcaner, Tevfik Avci, Murat Kus, Mehmet Abdussamet Bozkurt, Adem Ozcan, Nezihe Berrin Dodur Onalan, Serhan Yilmaz, Yasin Kara, Ali Kocatas, Fatih Yanar, Ali Fuat Kaan Gok, Irem Karatas, Berke Sengun, Ilknur Erenler Bayraktar, Onur Bayraktar, Zulal Emsal, Irem Dalkilic, Cengiz Dibekoglu, Sami Acar, Erman Ciftci, Yunus Yapalak, Cihad Tatar, Mert Mahsuni Sevinc, Ali Emre Nayci, Egemen Saygili, Yavuz Selim Komek, Bayram Kaymak, Fatih Altintoprak, Emrah Akin, Necattin Firat, Emre Gonullu, Ugur Can Dulger, Atilla Kurt, Sinan Soylu, Musa Serin, Omer Topcu, Ali Cihat Yildirim, Mehmet Fatih Ekici, Sezgin Zeren, Ismail Ahmet Bilgin, Tayfun Karahasanoglu, Ismail Hamzaoglu, Afag Aghayeva, Bilgi Baca, Inci Sahin, Osman Bozbiyik, Mustafa Ozgur Kilincarslan, Mustafa Ali Korkut, Erhan Akgun, Cemil Caliskan, Tayfun Yoldas, Timucin Erol, Hilmi Anil Dincer, Omer Cennet, Muhammed Salih Suer, Muhammet Bunyamin Dalkilic, Ibrahim Alkan, Busenur Kirimtay, Emre Balik, Emre Ozoran, Ibrahim Halil Ozata, Derya Salim Uymaz, Tutku Tufekci, Salih Nafiz Karahan, Orhan Agcaoglu, Naciye Cigdem Arslan, Mehmet Yilmaz, Orhan Ureyen, Can Murat Kale, Enver Ilhan, Eray Kara, Semra Tutcu Sahin, Onur Haspolat, Alperen Dalkiran, Ergun Yuksel, Mehmet Kocaoglu, Omer Tasan, Cevdet Tokat, Cihan Ozen, Alptug Mertcan Koc The Original article has been corrected.</p
Correction to:Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY)
No full textThe collaborative Author names are missing in the published proof. The Supplementary material is updated with 2 additional names in the collaborative Author’s list. Ali Yalcinkaya, Ahmet Yalcinkaya, Sezai Leventoglu, Bengi Balci, Alp Ozgun Borcek, Elif Ozeller, Ece Ozturk, Gulsum Sueda Kayacan, Berkay Enes Karaca, Ahmet Faruk Oyanik, Omer Faruk Gul, Basak Bolukbasi, Huseyin Gobut, Cagri Buyukkasap, Aydin Yavuz, Dara Aydin, Zeynep Akdagcik, Alina Pataeva, Douigou Hasan, Omar Hussein, Arda Ozgur Ozturk, Cem Arda Elumar, Ali Derman Dere, Asra Zeynep Balci, Rasim Ozturk, Yasar Copelci, Murat Kartal, Serkan Tayar, Mustafa Yeni, Tolga Kalayci, Ramazan Yavuz, Bulent Calik, Semra Demirli Atici, Selen Ozturk, Gizem Kilinc, Korhan Tuncer, Cengiz Aydin, Mustafa Yener Uzunoglu, Alp Yildiz, Aybala Yildiz, Can Sahin, Mehmet Caglikulekci, Elbrus Zarbaliyev, Murat Sevmis, Baris Sevinc, Nurullah Damburaci, Omer Karahan, Ozgen Isik, Said Kural, Xhenet Hysejni, Ahmet Aktas, Baris Yildiz, Gultekin Ozan Kucuk, Ahmet Can Sari, Mert Candan, Mehmet Mahir Ozmen, Cem Emir Guldogan, Emre Gundogdu, Munevver Moran, Mevlut Recep Pekcici, Saygin Altiner, Enes Cebeci, Tugba Yigit, Bedri Burak Sucu, Mert Col, Omer Faruk, Ozkan Hanife, Seyda Ulgur, Murat Kalin, Emre Furkan Kirkan, Abdullah Yildiz, Sema Yukseksag, Cagri Buyukkasap, Erdinc Kamer, Mesut Ozogul, Nihan Acar, Melek Gokova Bekler, Arif Atay, Halis Bag, Server Sezgin Uludag, Ahmet Necati Sanli, Sefa Ergun, Ergin Erginoz, Veysi Basbayandur, Mehmet Faik Ozcelik, Ahmet Askar, Yuksel Altinel, Adnan Hacim, Serhat Meric, Merve Tokocin, Talar Aktokmakyan, Yunus Aktimur, Kamil Ozdogan, Fikret Calikoglu, Tugba Koc Calikoglu, Ahmet Barcin, Ahmed Salhat, Guray Durmaz, Volkan Ozben, Erman Aytac, Zumrud Aliyeva, Arda Ulas Mutlu, Mert Tanal, Mustafa Fevzi Celayir, Aydin Eray, Tufan Ali Yuksel, Elif Baran, Banu Yigit, Erhan Eroz, Aykhan Abbasov, Hakan Yanar, Huseyin Onur Aydin, Murathan Erkent, Tugan Tezcaner, Tevfik Avci, Murat Kus, Mehmet Abdussamet Bozkurt, Adem Ozcan, Nezihe Berrin Dodur Onalan, Serhan Yilmaz, Yasin Kara, Ali Kocatas, Fatih Yanar, Ali Fuat Kaan Gok, Irem Karatas, Berke Sengun, Ilknur Erenler Bayraktar, Onur Bayraktar, Zulal Emsal, Irem Dalkilic, Cengiz Dibekoglu, Sami Acar, Erman Ciftci, Yunus Yapalak, Cihad Tatar, Mert Mahsuni Sevinc, Ali Emre Nayci, Egemen Saygili, Yavuz Selim Komek, Bayram Kaymak, Fatih Altintoprak, Emrah Akin, Necattin Firat, Emre Gonullu, Ugur Can Dulger, Atilla Kurt, Sinan Soylu, Musa Serin, Omer Topcu, Ali Cihat Yildirim, Mehmet Fatih Ekici, Sezgin Zeren, Ismail Ahmet Bilgin, Tayfun Karahasanoglu, Ismail Hamzaoglu, Afag Aghayeva, Bilgi Baca, Inci Sahin, Osman Bozbiyik, Mustafa Ozgur Kilincarslan, Mustafa Ali Korkut, Erhan Akgun, Cemil Caliskan, Tayfun Yoldas, Timucin Erol, Hilmi Anil Dincer, Omer Cennet, Muhammed Salih Suer, Muhammet Bunyamin Dalkilic, Ibrahim Alkan, Busenur Kirimtay, Emre Balik, Emre Ozoran, Ibrahim Halil Ozata, Derya Salim Uymaz, Tutku Tufekci, Salih Nafiz Karahan, Orhan Agcaoglu, Naciye Cigdem Arslan, Mehmet Yilmaz, Orhan Ureyen, Can Murat Kale, Enver Ilhan, Eray Kara, Semra Tutcu Sahin, Onur Haspolat, Alperen Dalkiran, Ergun Yuksel, Mehmet Kocaoglu, Omer Tasan, Cevdet Tokat, Cihan Ozen, Alptug Mertcan Koc The Original article has been corrected.</p
Correction to:Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY)
No full textThe collaborative Author names are missing in the published proof. The Supplementary material is updated with 2 additional names in the collaborative Author’s list. Ali Yalcinkaya, Ahmet Yalcinkaya, Sezai Leventoglu, Bengi Balci, Alp Ozgun Borcek, Elif Ozeller, Ece Ozturk, Gulsum Sueda Kayacan, Berkay Enes Karaca, Ahmet Faruk Oyanik, Omer Faruk Gul, Basak Bolukbasi, Huseyin Gobut, Cagri Buyukkasap, Aydin Yavuz, Dara Aydin, Zeynep Akdagcik, Alina Pataeva, Douigou Hasan, Omar Hussein, Arda Ozgur Ozturk, Cem Arda Elumar, Ali Derman Dere, Asra Zeynep Balci, Rasim Ozturk, Yasar Copelci, Murat Kartal, Serkan Tayar, Mustafa Yeni, Tolga Kalayci, Ramazan Yavuz, Bulent Calik, Semra Demirli Atici, Selen Ozturk, Gizem Kilinc, Korhan Tuncer, Cengiz Aydin, Mustafa Yener Uzunoglu, Alp Yildiz, Aybala Yildiz, Can Sahin, Mehmet Caglikulekci, Elbrus Zarbaliyev, Murat Sevmis, Baris Sevinc, Nurullah Damburaci, Omer Karahan, Ozgen Isik, Said Kural, Xhenet Hysejni, Ahmet Aktas, Baris Yildiz, Gultekin Ozan Kucuk, Ahmet Can Sari, Mert Candan, Mehmet Mahir Ozmen, Cem Emir Guldogan, Emre Gundogdu, Munevver Moran, Mevlut Recep Pekcici, Saygin Altiner, Enes Cebeci, Tugba Yigit, Bedri Burak Sucu, Mert Col, Omer Faruk, Ozkan Hanife, Seyda Ulgur, Murat Kalin, Emre Furkan Kirkan, Abdullah Yildiz, Sema Yukseksag, Cagri Buyukkasap, Erdinc Kamer, Mesut Ozogul, Nihan Acar, Melek Gokova Bekler, Arif Atay, Halis Bag, Server Sezgin Uludag, Ahmet Necati Sanli, Sefa Ergun, Ergin Erginoz, Veysi Basbayandur, Mehmet Faik Ozcelik, Ahmet Askar, Yuksel Altinel, Adnan Hacim, Serhat Meric, Merve Tokocin, Talar Aktokmakyan, Yunus Aktimur, Kamil Ozdogan, Fikret Calikoglu, Tugba Koc Calikoglu, Ahmet Barcin, Ahmed Salhat, Guray Durmaz, Volkan Ozben, Erman Aytac, Zumrud Aliyeva, Arda Ulas Mutlu, Mert Tanal, Mustafa Fevzi Celayir, Aydin Eray, Tufan Ali Yuksel, Elif Baran, Banu Yigit, Erhan Eroz, Aykhan Abbasov, Hakan Yanar, Huseyin Onur Aydin, Murathan Erkent, Tugan Tezcaner, Tevfik Avci, Murat Kus, Mehmet Abdussamet Bozkurt, Adem Ozcan, Nezihe Berrin Dodur Onalan, Serhan Yilmaz, Yasin Kara, Ali Kocatas, Fatih Yanar, Ali Fuat Kaan Gok, Irem Karatas, Berke Sengun, Ilknur Erenler Bayraktar, Onur Bayraktar, Zulal Emsal, Irem Dalkilic, Cengiz Dibekoglu, Sami Acar, Erman Ciftci, Yunus Yapalak, Cihad Tatar, Mert Mahsuni Sevinc, Ali Emre Nayci, Egemen Saygili, Yavuz Selim Komek, Bayram Kaymak, Fatih Altintoprak, Emrah Akin, Necattin Firat, Emre Gonullu, Ugur Can Dulger, Atilla Kurt, Sinan Soylu, Musa Serin, Omer Topcu, Ali Cihat Yildirim, Mehmet Fatih Ekici, Sezgin Zeren, Ismail Ahmet Bilgin, Tayfun Karahasanoglu, Ismail Hamzaoglu, Afag Aghayeva, Bilgi Baca, Inci Sahin, Osman Bozbiyik, Mustafa Ozgur Kilincarslan, Mustafa Ali Korkut, Erhan Akgun, Cemil Caliskan, Tayfun Yoldas, Timucin Erol, Hilmi Anil Dincer, Omer Cennet, Muhammed Salih Suer, Muhammet Bunyamin Dalkilic, Ibrahim Alkan, Busenur Kirimtay, Emre Balik, Emre Ozoran, Ibrahim Halil Ozata, Derya Salim Uymaz, Tutku Tufekci, Salih Nafiz Karahan, Orhan Agcaoglu, Naciye Cigdem Arslan, Mehmet Yilmaz, Orhan Ureyen, Can Murat Kale, Enver Ilhan, Eray Kara, Semra Tutcu Sahin, Onur Haspolat, Alperen Dalkiran, Ergun Yuksel, Mehmet Kocaoglu, Omer Tasan, Cevdet Tokat, Cihan Ozen, Alptug Mertcan Koc The Original article has been corrected.</p
Distribution of first and last author sex.
No full textArtificial intelligence (AI) and machine learning are central components of today’s medical environment. The fairness of AI, i.e. the ability of AI to be free from bias, has repeatedly come into question. This study investigates the diversity of members of academia whose scholarship poses questions about the fairness of AI. The articles that combine the topics of fairness, artificial intelligence, and medicine were selected from Pubmed, Google Scholar, and Embase using keywords. Eligibility and data extraction from the articles were done manually and cross-checked by another author for accuracy. Articles were selected for further analysis, cleaned, and organized in Microsoft Excel; spatial diagrams were generated using Public Tableau. Additional graphs were generated using Matplotlib and Seaborn. Linear and logistic regressions were conducted using Python to measure the relationship between funding status, number of citations, and the gender demographics of the authorship team. We identified 375 eligible publications, including research and review articles concerning AI and fairness in healthcare. Analysis of the bibliographic data revealed that there is an overrepresentation of authors that are white, male, and are from high-income countries, especially in the roles of first and last author. Additionally, analysis showed that papers whose authors are based in higher-income countries were more likely to be cited more often and published in higher impact journals. These findings highlight the lack of diversity among the authors in the AI fairness community whose work gains the largest readership, potentially compromising the very impartiality that the AI fairness community is working towards.</div
A novel semantic smoothing kernel for text classification with class-based weighting
No full textAltınel, Berna (Dogus Author), Diri, Banu (Dogus Author), Ganiz, Murat Can (Dogus Author) -- #articleinpress#Altınel, Berna (Dogus Author), Diri, Banu (Dogus Author), Ganiz, Murat Can (Dogus Author)In this study, we propose a novel methodology to build a semantic smoothing kernel to use with Support Vector Machines (SVM) for text classification. The suggested approach is based on two key concepts; class-based term weighting and changing the orthogonality of vector space. A class-based term weighting methodology is used for transformation of documents from the original space to the feature space. This class-based weighting basically groups terms based on their importance for each class and consequently smooths the representation of documents. This is accomplished by changing the orthogonality of the Vector Space Model (VSM) with introducing class-based dependencies between terms. As a result, on the extreme case, two documents can be seen as similar even if they do not share any terms but their terms are similarly weighted for a particular class. The resulting semantic kernel can directly make use of class information in extracting semantic information between terms, therefore it can be considered as a supervised kernel. For our experimental evaluation, we analyze the performance of the suggested kernel with a large number of experiments on benchmark textual datasets and present results with respect to varying experimental conditions. To the best of our knowledge, this is the first study to use class-based term weighting in order to build a supervised semantic kernel for SVM. We compare our results with kernels that are commonly used in SVM such as linear kernel, polynomial kernel, Radial Basis Function (RBF) kernel and with several corpus-based semantic kernels. According to our experimental results the proposed method favorably improves classification accuracy over linear kernel and several corpus-based semantic kernels in terms of both accuracy and speed
Percutaneous endoscopic gastrostomy experience in a general surgery clinic
No full textBackground: Percutaneous endoscopic gastrostomy is the most preferable procedure for nutritional support in patients starving for a long time, who have difficulty in swallowing or feeding by oral way due to various diseases. The seven years' experience of this surgery clinic was obtained in this study.Methods: The indications, complications and long term follow-up were recorded by physicians for 130 patients who had undergone percutaneous endoscopic gastrostomy. We used standart pull method for lite application of gastrostomy.Results: Percutaneous endoscopic gastrostomy was performed successfully in 82 (63%) chronic neurological patients, 22 (17%) patients with malignancy and 26 (20%) patients with various diseases with especially long time ventilation. It was performed on 93 male and 37 female patients, with a median age of 50.7 years (range 14-90 years). Ninety five (total mortality 73%) patients died because of the primary disease and after being discharged from the hospital. There was no mortality attributable to the procedure. The median time the patients used percutaneous endoscopic gastrostomy was 98.4 days (range 1-518 days) excluding 21 (16%) patients in whom the communication was lost during follow-up. There were a catheter leakage early in 12 and later in 9 patients, unsettled cathether in 8 patients, obstruction in 2 patients and catheter area inflamation in 2 patients. PEG was performed twice in 3 patients.Conclusion: Percutaneous endoscopic gastrostomy is a safe and reliable procedure for enteral feeding. The important complications are generally related to catheter care. In order to reduce complicatoins in the long run, further education of caretakers of patients and organization of the nutrition outpatient unit is advisable
Comparison of Intra-operative Pressure-Controlled Ventilation and Volume-Controlled Ventilation in Bariatric Surgery: A Prospective Randomized Study
No full textBackground: Mechanical ventilation may be particularly challenging in obese patients undergoing laparoscopic bariatric surgery. The present study aimed to compare the effects of pressure-controlled ventilation (PCV) with those of volume-controlled ventilation (VCV) on peripheral tissue oxygenation (PTO), respiratory function, hemodynamic status, and ventilation-related complications in patients undergoing laparoscopic bariatric surgery
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