14,670 research outputs found
CL-20 hosted in graphene foam as a high energy material with low sensitivity
No full textCL-20/graphene foam (GF) with a guest/host architecture was obtained by in situ crystallization of CL-20 in GF. With high detonation performance (44.1 GPa, 9687 m s(-1)), the CL-20/GF composite (98/2, w/w) is much less sensitive (IS: 4.5 J, FS: 252 N, ES: 0.72 J) than CL-20 (IS: 2.0 J, FS: 108 N, ES: 0.13 J)
Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: a retrospective study.
No full textOptimal budget allocation policy for tabu search in stochastic simulation optimization
No full textTabu search (TS) is a powerful method for solving combinatorial optimization problems. However, when TS is adopted for stochastic simulation optimization, the simulation noises may mislead the search direction and prevent TS from converging to high-quality solutions. This issue can be mitigated by increasing the number of simulation samples used for solution evaluation, however, real-world applications are generally constrained by a finite computing budget. Therefore, it is critical to reducing the noise effect by an efficient simulation budget allocation, i.e., splitting the total number of samples on solutions. Studies on the budget allocation problem of TS are sparse. Most of the works employ equal allocation or simple policies which are not optimal. Based on the large deviations framework, we propose a new budget allocation policy to enhance the performance of TS under stochastic settings. The proposed allocation policy, provided in closed-form formulas, is asymptotically optimal for maximizing the probability that TS performs the correct move in a single iteration. The efficiency of the proposed method is validated by solving different problems from manufacturing and healthcare scenarios, including an inventory control problem, a throughput maximization problem for the production line, and a physician scheduling problem for the radiotherapy center. The numerical results show that, with the proposed method, TS can obtain better results using the same amount of computational efforts
Concomitant aseptic subcutaneous abscess and immunoglobulin-mediated nephropathy--rare extra-intestinal manifestations in ulcerative colitis.
No full textEffects of amphetamine on the AMPA-mediated synaptic activity and the expression of AMPA receptor subunit 2 of brain neurons.
No full textLupus-related advanced liver involvement as the initial presentation of systemic lupus erythematosus.
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Spontaneous transfer of surface-expressed lactoferrins from polymorphonuclear neutrophils to autologous CD4+T cells after cell-cell contact for modulating Th1/Th2 cytokine expression.
No full textAnti-CD45 antibody enhances lipoxygenase pathway of human naive mononuclear cells and cyclooxygenase pathway of neutrophils.
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