60,795 research outputs found

    I醣抗原轉化基因的突變與白內障的生成(3/3)

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    The human i and I antigens are characterized as linear and branched repeats of N-acetyllactosamine, respectively. Conversion of the i to the I structure requires I-branching β-1,6-N-acetylglucosaminyltransferase activity. It has been noted that the null phenotype of I, the adult i phenotype, is associated with congenital cataracts in Asians. Previously, the identification of molecular changes in the IGnT gene, associated with the adult i phenotype, has been reported. In the present study, it has been demonstrated that the human I locus express three IGnT forms, designated IGnTA, IGnTB, and IGnTC, which have different exon 1, but identical exons 2 and 3, coding regions. The molecular genetics proposed for the I locus offers a new perspective of the formation and expression of the I antigen in different cells, and provides an insight into the questions derived from investigation of the adult i phenotype. Molecular genetic analyses of the I loci of the two adult i groups, with and without congenital cataracts, were performed, and enzyme function assays and expression patterns for the three IGnT transcripts in reticulocytes and lens-epithelium cells were analyzed. The results suggest a molecular genetic mechanism which may explain the partial association of the adult i phenotype with congenital cataracts, and indicating that a defect in the I locus may lead directly to the development of congenital cataracts. The results also suggest that the human blood group I gene should be re-assigned to the IGnTC form, not the IGnTB, as has previously been described

    The political role of the people's liberation army 1949-1973

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    This thesis is to study the political role of the People's Liberation Army from the approach of structure and function. The framework of the thesis consists of three major parts, first, the influence of Chinese traditional political culture on, and the formation of, the political role of the PL A; second, the influence of domestic political struggles and external military conflicts on the development of the political role of the PLA; and the third, the analysis of the transition of the PLA's political role from the structure and personnel arrangements of the CCPCC Within the above-mentioned three scopes, this thesis make a thorough discussion on the following: (1) The relationship between the structure of the PRC and the formation of the PLA's political role; (2) How has ideology influenced the army's political role; (3) What is Mao's viewpoint and his influence on the development of the army's political role; (4) What is the link between the army and the party, and how has this developed; (6) What accounts for the expansion of the PLA's political functions; (7) What is the influence of political factional struggles on the PLA's political role; (8) Is it political institution or military institution that controls the recruitment of the military elite; (9) What are the disparities between the military elite in handling international conflicts and what are their political considerations; (10) What is the Party's position in the army; (11) How have the Party’s important meetings and personnel arrangements influenced the rise and fall of the PLA's political role

    Molecular genetics of the blood group I system and the regulation of I antigen expression during erythropoiesis and granulopoiesis.

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    [[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=1065-6251&DestApp=JCR&RQ=IF_CAT_BOXPLO

    sj-docx-1-tam-10.1177_17588359231221907 – Supplemental material for Major adverse cardiovascular events in advanced-stage lung cancer: a multicenter cohort study

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    Supplemental material, sj-docx-1-tam-10.1177_17588359231221907 for Major adverse cardiovascular events in advanced-stage lung cancer: a multicenter cohort study by Chih-Hao Chang, Shih-Hao Huang, Hung-Yu Huang, Meng-Hung Lin, Chung-Shu Lee, Hsin-Fu Lee, Jason Chia-Hsun Hsieh and Chun-Yu Cheng in Therapeutic Advances in Medical Oncology</p

    Xinjiang (China), folk dancing of Uyghurs

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    Folk-dance of UighursImage is part of research conducted by Chang Chih-Yi for the article: Land Utilization and Settlement Possibilities in Sinkiang Author(s): Chang Chih-Yi Source: Geographical Review, Vol. 39, No. 1 (Jan., 1949), pp. 57-75 Published by: American Geographical Society Stable URL: http://www.jstor.org/stable/211157http://www.jstor.org/stable/211157Grayscal
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