225 research outputs found
Corrigendum to ‘Thiophene donor for NIR-II fluorescence imaging guided photothermal/photodynamic/chemo combination therapy’ [Acta Biomaterialia 127 (2021) 287-297]
No full textThe authors regret to report that the affiliation for author Dewen Liu was published incorrectly. The correct affiliation is as follows: Artemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. The authors apologise for any inconvenience caused.link_to_subscribed_fulltex
The underlying mechanisms of Jie-Du-Hua-Yu granule for protecting rat liver failure
No full textHua Qiu,1 Dewen Mao,1 Nong Tang,2 Fuli Long,1 Rongzhen Zhang,1 Minggang Wang,1 Qinglan Shi,1 Jiahuan Li,1 Qin Jiang,1 Yueqiao Chen,1 Xiufeng Wang1 1Department of Liver Disease, The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning, Guangxi 530023, China; 2Graduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi 530200, China Objectives: Jie-Du-Hua-Yu (JDHY) granule is a combination of six traditional Chinese medicines with known therapeutic effect in treating acute liver failure (ALF). The aim of this study was to investigate the amelioration efficacy of JDHY in lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced ALF in rat and explore the possible molecular mechanism underlying the therapeutic efficacy.Materials and methods: The efficacy of JDHY was determined by assessing hepatic pathology and function in LPS and D-GalN challenged Wistar rat. We also evaluated the effect of JDHY on LPS-induced Kupffer cells by measuring inflammatory cytokines and determining the phenotypic function. By means of bioinformatics analysis of liver tissue and validation in Kupffer cells, we identified possible pathways involved in the pharmacologic action of mechanism of JDHY.Results: JDHY could attenuate LPS-induced liver injury in rat by inhibiting apoptosis and increasing hepatic activity. In vitro study showed that JDHY could decrease the production of proinflammatory cytokines (tumor necrosis factor-α, IL6, and interferon-γ), increase anti-inflammatory cytokines (IL10, IL13), and promote cell survival and proliferation, possibly due to inhibition of IκB/nuclear factor-κB (NF-κB) signaling pathway and expression of CD14 and CXCL2, which was consistent with the findings from bioinformatics analysis.Conclusion: Our results revealed that JDHY protected against LPS-induced liver damage both in vitro and in vivo, by inhibiting the NF-κB-mediated inflammatory pathway, indicating its potential function to treat liver diseases. Keywords: JDHY, liver failure, NF-κB
 
Migration, Labor Market Flexibility, and Wage Determination in China: A Review
No full textThis paper reviews economic studies on rural-urban migration issues in China. The paper focuses on four issues: the household registration system in China, the profile of the migrants, explanations for rural-to-urban migration, and the interaction between migration and labor market evolution, with special reference to labor market segregation, labor market flexibility, and wage differentials. The paper concludes with suggestions for further research topics.Migration, Labor Market, Segregation, Mobility, China
Inequality and Internal Migration in China: Evidence from Village Panel Data
No full textThis paper analyzes the impact of rural-to-urban migration on income inequality and gender wage gap in source regions using a newly constructed panel dataset for around 100 villages over a ten-year period from 1997 to 2006 in China. Since income inequality is time-persisting, we use a system GMM framework to control for the lagged income inequality, in which contemporary emigration is also validly instrumented. We found a Kuznets (inverse U-shaped) pattern between migration and income inequality in the sending communities. Specifically, contemporary emigration increases income inequality, while lagged emigration has strong income inequalityreducing effect in the sending villages. A 50-percent increase in the lagged emigration rate translates into one-sixth to one-seventh standard deviation reduction in inequality. These effects are robust to the different specifications and different measures of inequality. More interestingly, the estimated relationship between emigration and the gender wage gap also has an inverse Ushaped pattern. Emigration tends to increase the gender wage gap initially, and then tends to decrease it in the sending villages.Internal Migration; Inequality; System GMM
Internal Migration and Income Inequality in China: Evidence from Village Panel Data
No full textExisting studies on the impact of migration on income inequality at sending communities suffer from severe methodology defects and data limitations. This paper analyzes the impact of rural-to-urban migration on inequality using a newly constructed panel dataset for around 100 villages over a ten-year period from 1997 to 2006 in China. To our best knowledge, this is the first paper that examines the dynamic aspects of migration and income inequality employing a dynamic panel data analysis. Unlike earlier studies focusing exclusively on remittances, our data include the total labor earnings of migrants in destination areas. Furthermore, we look at the gender dimension of the impact of migration on wage inequality within the sending communities. Since income inequality is time-persisting, we use a system GMM framework to control for the lagged income inequality in estimating the effect of emigration on income inequality in the sending villages. At the same time, contemporary emigration is validly instrumented in the GMM framework because of the unobserved time-varying community shock that correlates with emigration and income inequality, as well as with the potential reverse causality from income inequality to emigration. We found a Kuznets (inverse U-shaped) pattern between migration and income inequality in the sending communities. Specifically, contemporary emigration increases income inequality, while lagged emigration has strong income inequality-reducing effect in the sending villages. A 50-percent increase in the lagged emigration rate translates into one-sixth to one-seventh standard deviation reduction in inequality. Contemporary emigration has slightly smaller effects in raising the income inequality within villages. These effects are robust to the different specifications and different measures of inequality. More interestingly, the estimated relationship between emigration and the gender wage gap also has an inverse U-shaped pattern. Emigration tends to increase the gender wage gap initially, and then tends to decrease it in the sending villages.Internal Migration; Inequality; System GMM.
Author correction to ‘Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models’ [Acta Pharmaceutica Sinica B 11 (2021) 1903–1913]
No full textLncRNA SNHG16 promotes non‐small cell lung cancer development through regulating EphA2 expression by sponging miR‐520a‐3p
No full textEffects of Part Flexibility on Dynamic Behaviors of Machine Systems with Clearances in the Joints
No full textAuthor Correction: Origin and tuning of bandgap in chiral phononic crystals
No full textInternational audienceThere is a mistake in Figure 2 of the paper "Origin and tuning of bandgap in chiral phononic crystals (vol. 7, 272, 2024)". The original figure with a mistake is presented</div
- …
