19,066 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
Full text linkThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Performances of crosslinked asymmetric poly(vinyl alcohol) membranes for isopropanol dehydration by pervaporation
No full textAsymmetric poly(vinyl alcohol) (PVA) membranes crosslinked with glutaraldehyde (GA) were prepared by phase inversion technique for pervaporation dehydration of isopropanol (IPA). The crosslinking solutions contain sodium sulfate, sulfuric acid and different contents of GA, wherein sulfuric acid serves as a catalyst. The effects of three variables involved in the membrane preparation, including PVA molecular weight, PVA concentration and GA concentration on pervaporation characteristics were investigated. The results showed that the permeation flux decreases with the increase of these three factors, whereas the selectivity has an opposite trend. The influence of feed IPA concentration and temperature on pervaporation performances was also studied to find optimum operating conditions. (C) 2002 Elsevier Science B.V. All rights reserved.This work was supported by LG Chem. Ltd/BK 21 project. The authors wish to express their thanks. Dr Yu is also grateful to the Korea Foundation for Advanced Studies for a fellowship
ch-sa/labelCloud: v1.1.0
No full text<h2>What's Changed</h2>
<ul>
<li>Smaller Improvements by @ch-sa in https://github.com/ch-sa/labelCloud/pull/141</li>
<li>Fix testing pipeline by @ch-sa in https://github.com/ch-sa/labelCloud/pull/146</li>
<li>New hotkeys and bbox autoselection by @Divelix in https://github.com/ch-sa/labelCloud/pull/145</li>
<li>fixed KITTI dimensions by @ch-sa in https://github.com/ch-sa/labelCloud/pull/147</li>
<li>fix the changing problem of l,w,h by @spacewalk01 in https://github.com/ch-sa/labelCloud/pull/149</li>
<li>Remove python3.7 from test pipeline by @ch-sa in https://github.com/ch-sa/labelCloud/pull/150</li>
<li>Fix unit test badge in README by @ch-sa in https://github.com/ch-sa/labelCloud/pull/151</li>
</ul>
<h2>New Contributors</h2>
<ul>
<li>@spacewalk01 made their first contribution in https://github.com/ch-sa/labelCloud/pull/149</li>
</ul>
<p><strong>Full Changelog</strong>: https://github.com/ch-sa/labelCloud/compare/v1.0.1...v1.1.0</p>
Protection of infectious bronchitis virus relates to the N terminus of the spike protein.
No full textFatigue resistance analysis of tibial baseplate in total knee prosthesis- an in vitro biomechanical study
No full textRelatedness structure and individual identification in a semi-fossorial shrew (Soricidae: Anourosorex squamipes) using microsatellite markers.
No full textDistal Extension Denture – Case Report and Overview [Corrigendum]
No full textYeung C, Leung KCM, Yu OY, Lam WYH, Wong AWY, Chu CH. Clin Cosmet Investig Dent. 2020;12:493—503.
Details of the same case report were previously reported by the authors in Yeung C, Leung KCM, Yu OY, Lam WYH, Wong AWY, Chu CH. Prosthodontic Rehabilitation and Follow-Up Using Maxillary Complete Conventional Immediate Denture. Clin Cosmet Investig Dent. 2020;12:437–445.
Figures 1-5, 11 and 12-14 on pages 494, 496 and 497, respectively, should have included the following note:
Note: Copyright ©2020. Dove Medical Press. Reproduced from Yeung C, Leung KCM, Yu OY, Lam WYH, Wong AWY, Chu CH. Prosthodontic Rehabilitation and Follow-Up Using Maxillary Complete Conventional Immediate Denture. Clin Cosmet Investig Dent. 2020;12:437–445.
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Combined dunham analysis of rotational and eletronic transitions of CH+
Full text link"A Dunham analysis of the band was carried out by M\""{u}ller, and predictions of the pure rotational transition frequencies were made.\footnote{H. S. P. M\""{u}ller,\textit{A\&A},\textit{514}, L6(2010)}
More recently, in submillimeter to THz region, several rotational lines were observed for CH, CH, and CD.\footnote{T. Amano, \textit{Ap.J.Lett.}, \textbf{716}, L1 (2010)}\footnote{T. Amano, \textit{J. Chem. Phys.}, \textbf{133}, 244305 (2010)}\footnote{S. Yu et al,\textit{The 70th International Symposium on Moecular Spectroscopy}, \textbf{RD06}(2015)}
In this investigation, those newly obtained rotational lines are incorporated in the Dunham analysis.
The -doubling splittings in electronic states have been expressed as in most investigations.
However, it should be noted that the -levels of state interact with states, while the -levels with states.
For CH, the -levels of are pushed upward from the interaction with the ground state.
The states are not known experimentally and they, if any, should lie high over the state.
In this analysis, only the -levels are included in the least-squares analysis by neglecting the -doubling.
The mass independent parameters have been obtained, and the conventional spectroscopic parameters are derived for each isotopologue.
These results should be useful for determining the potential energies of this fundamental ion.\footnote{Y. S. Cho and R. J. LeRoy,\textit{J. Chem. Phys.},\textbf{144}, 024311(2016)}"Made available in DSpace on 2017-01-26T21:38:05Z (GMT). No. of bitstreams: 3
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Previous issue date: 2016-06-2
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Interaction of the westerlies with the Tibetan Plateau in determining the mei-yu termination Interaction of the westerlies with the Tibetan Plateau in determining the mei-yu termination
Full text linkThis study explores how the termination of the mei-yu is dynamically linked to the westerlies impinging on the Tibetan Plateau. It is found that the mei-yu stage terminates when the maximum upper tropospheric westerlies shift beyond the northern edge of the Plateau, around 40°?. This termination is accompanied by the disappearance of tropospheric northerlies over northeastern China. The link between the transit of the jet axis across the northern edge of the Plateau, the disappearance of northerlies, and termination of mei-yu holds on a range of timescales from interannual through seasonal and pentad. Diagnostic analysis indicates that the weakening of meridional moisture contrast and meridional wind convergence, mainly resulting from the disappearance of northerlies, causes the demise of the mei-yu front. The authors propose that the westerlies migrating north of the Plateau and consequent weakening of the extratropical northerlies triggers mei-yu termination. Model simulations are employed to test the causality between the jet and the orographic downstream northerlies by repositioning the northern edge of the Plateau. As the Plateau edge extends northward, orographic forcing on the westerlies strengthens, leading to persistent strong downstream northerlies and a prolonged mei-yu. Idealized simulations with a dry dynamical core further demonstrate the dynamical link between the weakening of orographically forced downstream northerlies with the positioning of the jet from south to north of the Plateau. Changes in the magnitude of orographically forced stationary waves are proposed to explain why the downstream northerlies disappear when the jet axis migrates beyond the northern edge of the Plateau
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