88 research outputs found
Elimination Reactions of (E)-2,4,6-Trinitrobenzaldehyde O-Aryloximes Promoted by R<sub>3</sub>N/R<sub>3</sub>NH<sup>+</sup>in 70 mol% MeCN(aq). Effect of β-Aryl Group the Nitrile-Forming Transition-State
No full textInstrumented Cone Penetrometer for Dense Layer Characterization
No full textSubsurface characterization is essential for a successful infrastructure design and construction. This paper demonstrates the use of an instrumented cone penetrometer (ICP) for a dense layer characterization at two sites. The ICP consists of a cone tip and rods equipped with an accelerometer and four strain gauges, which allow dynamic driving, in addition to quasi-static pushing of the cone. The force and velocity of the cone are measured using the ICP instrumentation and compared with the N value, dynamic cone penetration index, and static cone resistance. A strong correlation has been observed between the total cone resistance estimated from the ICP and the dynamic cone penetration index and static cone resistance. After the correction of the dynamic cone resistance effect, the static component of the total cone resistance can be used as an alternative to a static cone resistance. This novel approach of soil resistance estimation using the ICP may be useful for dense layer characterization
Apoptotic protein expression and cellular death in both exogenous Aβ<sub>1–42</sub> treatment and mito Aβ<sub>1–42</sub>–transfected cells.
No full text<p>Western blot analysis was performed in both exogenous Aβ<sub>1–42</sub> treatment and mito Aβ<sub>1–42</sub>–transfected HT22 cells to characterize the expression level of Aβ<sub>1–42</sub>, Bcl-2, Bax using 6E10, Bcl-2 antibody and Bax antibody (A). Expression level of Bcl-2 and Bax was confirmed in mitochondrial fraction (B). Different concentrations of mito Aβ<sub>1–42</sub> DNA constructs were used, 2 µg and 4 µg. Cytochrome C release assay (C) and calcein cell viability assay (D) were performed in vehicle-treated, exogenous Aβ<sub>1–42</sub>-treated, mock and mito Aβ<sub>1–42</sub> transfected HT22 cells, respectively (* p<0.05, ** p<0.01 compared with vehicle, # p<0.05 compared to mock).</p
Mitochondria-specific accumulation of mito Aβ<sub>1–42</sub>.
No full text<p>A. Western blot analysis showed the mitochondria-specific accumulation of Aβ<sub>1–42</sub> with the presence of TOM20, mitochondrial marker and the absence of β-actin. B. EM image of mitochondria in mock and mito Aβ<sub>1–42</sub>-transfected HT22 cells (yellow scale bar: 2 µm, white scale bar: 1 µm).</p
Al-Zn-Sn-O Thin Film Transistors with Top and Bottom Gate Structure for AMOLED
No full textWe have fabricated the transparent bottom gate and top gate TFTs using new oxide material of Al-Zn-Sn-O (AZTO) as an active layer. The AZTO active layer was deposited by RF magnetron sputtering at room temperature. Our novel TFT showed good TFT performance without post-annealing. The field effect mobility and the sub-threshold swing were improved by the post-annealing, and the mobility increased with SnO2 content. The AZTO TFT (about 4 mol% AlOx, 66 mol% ZnO, and 30 mol% SnO2) exhibited a mobility of 10.3 cm(2)/Vs, a turn-on voltage of 0.4 V. a sub-threshold swing of 0.6 V/dec, and an on/off ratio of 109. Though the bottom gate AZTO TFT showed good electrical performance, the bias stability was relatively poor. The bias stability was significantly improved in the top gate AZTO TFT. We have successfully fabricated the transparent AMOLED panel using the back-plane composed with top gate AZTO TFT array
Clathrin-mediated endocytosis blocker inhibited Aβ<sub>1–42</sub>-induced mitochondrial dysfunction.
No full text<p>A. Mitochondrial shapes were identified by immunostaining of HSP60 in vehicle, Aβ<sub>1–42</sub>, chlorpromazine+Aβ<sub>1–42</sub>, mouse anti-RAGE IgG+Aβ<sub>1–42</sub> treatment in HT22 cells, respectively (Scale bar: 20 µm). B. Altered mitochondrial shapes are quantified using form factor and aspect ratio (blue: vehicle, red: chlorpromazine+Aβ<sub>1–42</sub>, green: Aβ<sub>1–42</sub> in left graph). Four functional assessments of mitochondria are shown, including MTT (C), ROS levels (D), ATP generation (E) and TMRM intensity (F). * p<0.05, ** p<0.01, *** p<0.001 compared with vehicle, # p<0.05 compared with Aβ<sub>1–42</sub>.</p
Study of Activation Energy in Soil through Elastic Wave Velocity and Electrical Resistivity
No full textCharacteristics of elastic waves passing through a flowable fill at early age
No full textElastic waves obtained from transducers are widely used to monitor the strength and integrity of cementitious materials. A pair of bender elements (BEs) and piezo disk elements (PDEs) embedded in a cuboid mould are applied to monitor elastic waves passing through a cementitious material known as a flowable fill at early age. The flowable fills used in this study are mixed with calcium sulfoaluminate cement, sand, silt, fly ash, water, and an accelerator. Compressional and shear waves acquired from the PDEs and BEs, respectively, are observed for up to 72 hrs. Results show that the compressional and shear wave velocities increased with curing time. The sensors can be used effectively to monitor the hardening characteristics of flowable fills at early age, and the BEs are particularly suitable for evaluating the hardening conditions of flowable fills as a result of the wide variation in shear wave velocities
Modified Fixed Wall Oedometer When Considering Stress Dependence of Elastic Wave Velocities
No full textA modified oedometer cell for measuring the applied stresses and elastic waves at the top and bottom of the specimen is developed to evaluate the effect of the side friction on the stress dependence of the elastic wave velocities. In the modified cell, two load cells are installed at the top and bottom plates, respectively. To generate and detect the compressional and shear waves, a pair of piezo disk elements and a pair of bender elements are mounted at both the top and bottom plates. Experimental results show that the stresses measured at the bottom are smaller than those measured at the top during the loading and vice versa during unloading, regardless of the densities and heights of the specimens. Under nearly saturated conditions, the compressional wave velocities remain almost constant for the entire stress state. With plotting stresses measured at top, the shear wave velocities during unloading are greater than those during loading, whereas with plotting stresses measured at bottom, the shear wave velocities during unloading are smaller than those during loading owing to the side friction. The vertical effective stress may be simply determined from the average values of the stresses measured at the top and bottom of the specimens
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