529 research outputs found
ASM Journals Eliminate Impact Factor Information from Journal Websites
No full textFull author list omitted for brevity. For the full list of authors, see article.At the recent Journals Board meeting that took place during ASM Microbe 2016 in Boston, MA, the journal editors in chief and the American Society for Microbiology (ASM) leadership decided to no longer advertise the impact factors of ASM journals. This editorial was published simultaneously by the following ASM journals: Antimicrobial Agents and Chemotherapy, Applied and Environmental Microbiology, Clinical Microbiology Reviews, Infection and Immunity, Journal of Clinical Microbiology, mBio, Microbiology and Molecular Biology Reviews, mSphere, and mSystems
Enhanced Distal Radius Segmentation in DXA Using Modified ASM
No full textThe active shape model (ASM) has been widely adopted by automated bone segmentation approaches for radiographic images. In radiographic images of the distal radius, multiple edges are often observed in the near vicinity of the bone, typically caused by the presence of thin soft tissue. The presence of multiple edges decreases the segmentation accuracy when segmenting the distal radius using ASM. In this paper, we propose an enhanced distal radius segmentation method that makes use of a modified version of ASM, reducing the number of segmentation errors. To mitigate segmentation errors, the proposed method emphasizes the presence of the bone edge and downplays the presence of a soft tissue edge by making use of Dual energy X-ray absorptiometry (DXA). To verify the effectiveness of the proposed segmentation method, experiments were performed with 30 distal radius patient images. For the images used, compared to ASM-based segmentation, the proposed method improves the segmentation accuracy with 47.4% (from 0.974 mm to 0.512 mm)
Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
No full textAlthough many reports have revealed dysfunction of endothelial cells in aging, resulting in blood-brain barrier (BBB) breakdown, the underlying mechanism or mechanisms remain to be explored. Here, we find that acid sphingomyelinase (ASM) is a critical factor for regulating brain endothelial barrier integrity. ASM is increased in brain endothelium and/or plasma of aged humans and aged mice, leading to BBB disruption by increasing caveolae-mediated transcytosis. Genetic inhibition and endothelial-specific knockdown of ASM in mice ameliorated BBB breakdown and neurocognitive impairment during aging. Using primary mouse brain endothelial cells, we found that ASM regulated the caveolae-cytoskeleton interaction through protein phosphatase 1-mediated ezrin/radixin/moesin (ERM) dephosphorylation and apoptosis. Moreover, mice with conditional ASM overexpression in brain endothelium accelerated significant BBB impairment and neurodegenerative change. Overall, these results reveal a novel role for ASM in the control of neurovascular function in aging, suggesting that ASM may represent a new therapeutic target for anti-aging.
Prism tableaux and alternating sign matrices
No full textA. Lascoux and M.-P. Schutzenberger introduced Schubert polynomials to study the cohomology ring of the complete flag variety Fl(C^n). Each Schubert polynomial corresponds to the class defined by a Schubert variety X_w in Fl(C^n). Schubert polynomials are indexed by elements of the symmetric group and form a basis of the ring Z[x1,x2,...]. The expansion of the product of two Schubert polynomials in the Schubert basis has been of particular interest. The structure coefficients are known to be nonnegative integers. As of yet, there are only combinatorial formulas for these coefficients in special cases, such as the Littlewood-Richardson rule for multiplying Schur polynomials.
Schur polynomials form a basis of the ring of symmetric polynomials. They have a combinatorial formula as a weighted sum over semistandard tableaux. In joint work with A. Yong, the author introduced prism tableaux. A prism tableau consists of a tuple of tableaux, positioned within an ambient grid. With A. Yong, the author gave a formula for Schubert polynomials using prism tableaux. We continue the study of prism tableaux, detailing their connection to the poset of alternating sign matrices (ASMs).
Schubert polynomials can be interpreted as multidegrees of the matrix Schubert varieties of Fulton. We study a more general class of determinantal varieties, indexed by ASMs. More generally, one can consider subvarieties of the space of n by n matrices cut out by imposing rank conditions on maximal northwest submatrices. We show that, up to an affine factor, such a variety is isomorphic to an ASM variety. The multidegrees of ASM varieties can be expressed as a sum over prism tableaux.
In joint work with A. Yong and R. Rimanyi, the author studies representations of quivers and their connection to the dilogarithm identities of M. Reineke. We give a bijective proof to establish an identity of generating series. This bijection uses a generalization of Durfee squares. From this identity, we give a new proof of M. Reineke's identities in type A.Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2018-09-27 without embargo termsThe student, Anna Weigandt, accepted the attached license on 2018-07-03 at 01:58.The student, Anna Weigandt, submitted this Dissertation for approval on 2018-07-03 at 02:11.This Dissertation was approved for publication on 2018-07-03 at 12:06.DSpace SAF Submission Ingestion Package generated from Vireo submission #12714 on 2018-09-27 at 10:46:31Made available in DSpace on 2018-09-27T16:17:37Z (GMT). No. of bitstreams: 2
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Previous issue date: 2018-07-0
Early Biotechnology: The Delft Connection. Early Dutch microbiologists fostered their own golden age of microbiology
No full textInfluence of ultrasonic melt treatment on the formation of primary intermetallics and related grain refinement in aluminum alloys
No full textThis article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited - The article can also be accessed from the link below - Copyright @ 2011 SpringerUltrasonic melt treatment (UST) is known to induce grain refining in aluminum alloys. Previous studies have clearly shown that in Al-Zr-Ti alloys, the primary Al(3)Zr intermetallics were dramatically refined by cavitation-assisted fragmentation, and a good refinement effect was achieved. In this article, Al-Ti, Al-Ti-Zr alloys, and some commercial aluminum alloys are used to analyze the effect of UST on primary intermetallics and grain refinement. The addition of a small amount of Al-3Ti-B master alloy is also studied in order to compare with the addition of Ti and Zr in commercial aluminum alloys. Experimental results show that the ultrasonic grain refining effect is not only related to the size of particles which are refined and/or dispersed by UST, but also related to an undercooling available for activation of these particles in the solidification process. Athermal heterogeneous nucleation theory is considered to explain the effect of size and distribution of substrate particles on the grain structure with different undercoolings. The distribution of primary particle sizes results in the distribution of required undercoolings. Grain refining occurs when the undercooling is large enough to activate the refined primary intermetallics or dispersed inoculants.This study is supported by the Materials Innovation Institute and China Scholarship Counci
Rapid and Label-Free Optical Screening of Anthrax Spores Using Quantitative Phase Imaging and Deep Neural Network
No full textThree-Dimensional Label-Free Imaging of Individual Bacteria Using Optical Diffraction Tomography
No full textProceedings of Cardiff Institute for Tissue Engineering & Repair Annual Scientific Meeting (CITER ASM 2021)
No full textCITER ASM 2021
The abstracts appearing in this book comprise the proceedings of the CITER ASM 2021, held between the 13th and 14th of September 2021. The posters presented reflect the authors’ opinions and are published as presented and without change (formatting and minor editing expected). Their inclusion in this publication does not necessarily constitute endorsement by the editors, CITER, or the Cardiff University.
Please use the following format to cite material from these Proceedings:
Author, AB, Author, XY, and Author, DE (2021), Title of paper, Proc. Cardiff Institute for Tissue Engineering & Repair Annual Scientific Meeting (CITER ASM 2021), M Al-Amri, R Weiser (Eds), pp. a–b, Cardiff, UK, 13-14 Sept. 2021, ISSN 2634-100X
Proceedings reference number: ISSN 2634-100X
Published by Cardiff University
For information, contact: CITER, Cardiff University, Redwood Building, King Edward VII Avenue, CF10 3NB.
Email: [email protected]
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