28,148 research outputs found
Effects of Bufei Yishen formula on klotho gene expression and inflammation-related RIG-I/NF-κB pathway in cigarette smoke extract-treated BEAS-2B cells
No full textPurpose: To investigate the anti-inflammatory effect of Bufei yishen formula on chronic obstructive pulmonary disease (COPD) and klotho expression in cigarette smoke extract (CSE)-treated BEAS-2B cells.Methods: Cigarette smoke extract (CSE) was diluted in Dulbecco’s modified Eagle’s medium (DMEM) and used to treat a COPD cell model established using BEAS-2B cells. The CSE-treated cells were transfected with klotho overexpression plasmid, and the COPD cell model was treated with Bufei yishen formula. Dexamethasone was used as positive control. Changes in the expressions of klotho, RIG-I, and NF-ĸB were determined using reverse transcription-polymerase chain reaction (RT-PCR) and Western blotting, while enzyme linked immunosorbent assay (ELISA) was used to evaluate changes in the expressions of IL-6 and TNF-α.Results: Klotho expression level was reduced in COPD model. Overexpression of klotho inhibited the expressions of IL-6, TNF-α, RIG-I, NF-κB, but bufei yishen formula increased klotho expression level and decreased the expressions of RIG-I, NF-κB, IL-6 and TNF-α. However, after CSE treatment, the anti-inflammatory effect of the formula decreased significantly when klotho expression was knocked down.Conclusion: Bufei yishen formula possesses anti-inflammatory effects which are significantly decreased after klotho knockdown. This suggests that the formula probably acts by upregulating klotho expression, thereby down-regulating the expressions of IL-6 and TNF-α via RIG-I/NF-κB pathway.Keywords: Bufei yishen formula, COPD, Klotho, Inflammation, RIG-I/NF-κ
Chen Chen, 42nd Annual ODU Literary Festival
No full textChen Chen is the author of When I Grow Up I Want to Be a List of Further Possibilities (BOA Editions, 2017), which was long-listed for the National Book Award and won the Thom Gunn Award, among other honors. Bloodaxe Books published a UK edition in June. He is also the author of four chapbooks, most recently You MUST Use the Word Smoothie (Sundress Publications, 2019) and Gesundheit! (in collaboration with Sam Herschel Wein and forthcoming from Glass Poetry Press, fall 2019). His work appears in many publications, including Poem-a-Day, The Massachusetts Review, The Best American Poetry, and The Best American Nonrequired Reading. He has received a Pushcart Prize and fellowships from Kundiman and the National Endowment for the Arts. He holds an MFA from Syracuse University and a PhD from Texas Tech University. He teaches at Brandeis University as the Jacob Ziskind Poet-in-Residence and co-runs the journal, Underblong. He lives in Waltham, Massachusetts, with his partner, Jeff Gilbert, and their pug, Mr. Rupert Gile
Supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow-water dynamical core on generic gnomonic cubed-sphere geometry
No full text# Simulation results of the unstaggered shallow water model
This repository contains the supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow‐water dynamical core on generic gnomonic cubed‐sphere geometry, DOI: 10.1029/2020MS002280
Organization of the repository:
The tar archive with this data submission has a:
doc directory contains a README.md with information regarding naming conventions to label the model configurations for a shallow water test simulation. Additional information can also be found in README.md. Table 4 in the paper provides additional details.
The data directory contains the supporting data files (NetCDF format).Disclaimer: "This was prepared by Xi Chen under award NA18OAR4320123 from the National Oceanic and Atmospheric Administration, U.S. Department of Commerce. The statements, findings, conclusions, and recommendations are those of the author(s) and do not necessarily reflect the views of the National Oceanic and Atmospheric Administration, or the U.S. Department of Commerce.
Artimpaza brevilineata Tian & Chen, 2012 in Tian, Chen & Li 2012
No full textArtimpaza brevilineata Tian & Chen, 2012 in Tian, Chen & Li, 2012: 43, figs. 1–9. (Figs. 28a, b) Type locality: China, Yunnan, Pu’er City, Yutang. Gender: female. Date collected: 2011.V.25 (2010.V.25, in the original description, is incorrect). Collector: Li-Chao TIAN & Gui-Qiang HUANG. Paratypes: 1 female, China, Yunnan, Lincang City, 1980.VI.1, Fen LIU leg. Remarks: In the original description, the type locality is “ Yunnan, Jinghong” while it is “ Yunnan, Yutang” according to the label. “Yutang” is actually in Pu’er, not Jinghong. The first author described the type locality by mistake. In the original description, the collector was only listed as Li-Chao TIAN, which was a mistake.Published as part of Li, Zhu & Chen, Li, 2020, Primary types of longhorned beetles (Coleoptera, Cerambycidae, Vesperidae and Disteniidae) of Southwest University (SWU), pp. 25-46 in Zootaxa 4718 (1) on page 33, DOI: 10.11646/zootaxa.4718.1.2, http://zenodo.org/record/360220
Author contributions
No full textPlease browse the "Files" tag to access the appendix specifying the author - Chen Hsi Tsai's contributions to the seven papers included in the thesis
Ying Chen\u27s Impressions of Summer
No full textChapbook of narrative/personal poems by Ying Chen originally published by Finishing Line Press in 2013. Translated from the French by Peter Schulman, ODU Professor of French and International Studies.https://digitalcommons.odu.edu/worldlanguages_books/1016/thumbnail.jp
《在中法之间 — 陈伟农的艺术体验》 Zai Zhong Fa zhi jian: Chen Weinong de yishu tijian / “Between China and France. The Artistic Experience of Chen Weinong”
No full textThe author analizes the artistic production of the Chinese contemporary artist Chen Weinong, who has travelled between China and France for more ten years. In his ink paintings and calligraphies, Chen Weinong reflects the essence of both Western and Eastern cultures, succeeding in refreshing the ancient tradition as well as blazing new trails in Chinese art
Programmatic and performance observations for Two Chamber Works by Chen Yi
No full textAs a Chinese-American composer who was born and reared in China, then studied and settled in the United States, Chen Yi’s success is widely recognized around the world. However, this success is not coincidental and is closely related to her fusion of the Chinese and Western cultures in her works. At the time of this writing, Chen Yi has composed more than forty chamber works, from which the author researched two with the same instrumentation—flute, clarinet, violin, cello, and piano. By understanding Chen Yi’s life experiences and analyzing the theoretical aspects of these compositions, the author gives suggestions for ensemble, timbre, rhythm, pedaling, and performance techniques in these two chamber works by Chen Yi—Happy Rain on a Spring Night and … as like a raging fire
[Ping Lao She zuo pin]. 3
No full text[陳大鵬].Title and author supplied by cataloguer.Live recording.Electronic reproduction from Rulan Chao Pian Audio Cassette Collection.Spoken in Chinese.[Chen Dapeng]
Bambusananus yangae Xing & Chen 2013, nom. nov.
No full text<i>Bambusananus yangae</i> Xing & Chen, nom. nov. <p> <i>Bambusananus yangae</i>, <i>nomen novum</i> for <i>Bambusananus lii</i> Yang & Chen, 2012: 50, preoccupied by <i>Bambusananus lii</i> (McKamey & Hicks, 2007)</p> <p> The new name is based on the surname of the first author of the junior homonym. Accordingly, the genus <i>Bambusananus</i> currently includes the following species: <i>Bambusananus maculipennis</i> (Li & Wang, 1993), <i>Bambusananus bipunctatus</i> (Li, 1999), <i>Bambusananus lii</i> (McKamey & Hicks, 2007), <i>Bambusananus furcatus</i> Li & Xing, 2011 and <i>Bambusananus yangae</i> Xing & Chen, <b>nom. nov.</b>.</p>Published as part of <i>Xing, Ji-Chun & Chen, Xiang-Sheng, 2013, Nomenclatural changes in the genus Bambusananus Li & Xing, 2011 (Hemiptera: Cicadellidae: Deltocephalinae: Athysanini), pp. 599-600 in Zootaxa 3635 (5)</i> on page 599, DOI: 10.11646/zootaxa.3635.5.12, <a href="http://zenodo.org/record/5262395">http://zenodo.org/record/5262395</a>
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