462 research outputs found
A Golgi PKD Activity Reporter Reveals a Crucial Role of PKD in Nocodazole‐Induced Golgi Dispersal
No full textThe protein kinase D (PKD) family comprises multifunctional serine/threonine-specific protein kinases with three mammalian isoforms: PKD1, PKD2 and PKD3. A prominent PKD function is the regulation of basolateral-targeted transport carrier fission from the trans-Golgi network (TGN). To visualize site-specific PKD activation at this organelle, we designed a molecular reporter consisting of a PKD-specific substrate sequence fused to enhanced green fluorescent protein (EGFP), specifically targeted to the TGN via the p230 GRIP domain. Quantitative analyses using a phosphospecific antibody and ratiometric fluorescence imaging revealed that Golgi-specific phosphorylation of the reporter was strictly dependent on stimulation of endogenous PKD or transient expression of active PKD constructs. Conversely, PKD-specific pharmacological inhibitors and siRNA-mediated PKD knockdown suppressed reporter phosphorylation. Using this reporter we investigated a potential role for PKD in the regulation of Golgi complex morphology. Interestingly, nocodazole-induced Golgi complex break-up and dispersal was associated with local PKD activation as measured by reporter phosphorylation and this was efficiently blocked by expression of a dominant-negative PKD mutant or PKD depletion. Our data thus identify a novel link between PKD activity and the microtubule cytoskeleton, whereby Golgi complex integrity is regulated
O Raposo do Goethe : uma proposta de tradução do Reineke Fuchs
No full textOrientador: Prof. Dr. Marcelo Paiva de SouzaDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Humanas, Programa de Pós-Graduação em Letras. Defesa : Curitiba, 14/08/2017Inclui referências: p. 255-260Área de concentração: Estudos literáriosResumo: N este trabalho propõe-se um projeto de tradução da prim eira metade da versão de Johann Wolfgang von Goethe do épico zoológico Reineke Fuchs (1794) para o português brasileiro. Tendo em vista essa empreitada tradutória serão apresentados: o momento político da escrita do épico, i.e., o período mais violento da Revolução Francesa, e suas possíveis reverberações no poem a épico; o lugar da versão de Goethe dentro do contexto da tradição de língua alemã dos épicos de Reineke; e as inovações, sobretudo no artesanato poético, realizadas neste poem a em relação aos textos-base de Goethe, que reescreveu o poem a a partir, principalmente, da tradução para o alto-alemão do Reynke de Vos feita por Johann Christoph Gottsched e publicada em Heinrichs von Alkm ar Reineke der Fuchs (1752), que era acompanhada pelo original médio-baixo-alemão. Será considerada ainda a relação da remodelagem poética com o metro escolhido para o poema, o hexâm etro datílico. Também será discutida no trabalho, tom ando como ponto de partida as considerações sobre tradução do próprio Goethe, a dificuldade de se classificar ou delimitar o caráter tradutório no poem a em questão. Serão ainda apresentados os procedimentos gerais de tradução apreensíveis nas outras traduções do Reineke de Goethe, com especial atenção às traduções em língua portuguesa, sobretudo à tradução brasileira. Ao final do percurso, será esclarecida a proposta de tradução levada a cabo no trabalho e apresentado, à guisa de conclusão, o poem a traduzido seguido de notas. Palavras-chave: Tradução. Poesia épica. H exâmetro datílico. Johann Wolfgang von Goethe. Reineke Fuchs.Abstract: This master thesis presents a translation project o f the first half o f Johann Wolfgang von G oethe's version o f the beast epic Reineke Fuchs (1794) into Brazilian Portuguese. Having this translational enterprise in mind, there will be presented: the political background in which the epic poem was written, i.e., the m ost violent period o f the French Revolution, and the possible im pact that the event had on the epic poem; the place o f G oethe's version inside the German language tradition o f the Reineke epics; and the inovations, especially regarding poetic construction, performed in this poem in comparison to G oethe's source-texts, since the author wrote the poem following primarily Johann Christoph Gottsched's High German translation o f Reynke de Vos, published in H einrichs von Alkm ar Reineke der Fuchs (1752), which included the original Low M iddle German poem. The connection between the poetic reshaping and the meter, the Dactylic Hexameter, chosen for this poem will also be taken into consideration. This thesis will discuss as well the dificulties in classifying or delimiting the translational aspect o f the poem in question, taking as a starting point G oethe's own reflexions about translation. The general translation processes found in other translations o f G oethe's Reineke will be presented, with especial atention to the translations into Portuguese, especially the Brazilian translation. At the end o f this work the translation proposal that is presented here will be explained and the translated poem, followed by notes, delivered by way of conclusion. Keywords: Translation. Epic Poetry. Dactylic Hexameter. Johann Wolfgang von Goethe. Reineke Fuchs
COTORSION MODULES OVER NOETHERIAN HEREDITARY RINGS
No full textCotorsion abelian groups form an important class of abelian groups for which nice structure theorems are known. They have been discussed at length by Harrison [7], Nunke [13] and the author [3]. Cotorsion modules over integral domains have been investigated by Matlis [10]. Some of his results have been extended to arbitrary commutative rings by Henderson and Orzech [8]; they replaced the classical notion of "torsion " by a torsion theory. We also start with a torsion theory with respect to which we define T-cotorsion modules; our aim is to obtain analogues of the relevant structure theorems on cotorsion groups when the base ring is noetherian and hereditary (it can have divisors of zero and can be non-commutative). In õ 1 we give various characterizations of T-cotorsion modules and establish their fundamental properties. Then we turn our attention to the embedding of modules in T-cotorsion modules such that the quotients are T-free; our approach has to be different from what is used in abelian group theory where the functor Extlz(Q/Z, *) yields such an embedding. Properties of the T-cotorsion hulls are investigated in õ3 as a prelude to the structure theory developed in õ4. Though we do not assume throughout that the base rings are noetherian and hereditary, the highlights of our results are established only for noetherian hereditary rings. Observe that examples for such rings are abundant: Dedekind domains as well as matrix rings and triangular matrix rings over them (cf. Chase [1], Fuelberth and Kuzmanovich [ 5] and the literature cited there), etc. õ 1. In the category of unital left R-modules, let (T,F) be a hereditary torsion theory in the sense of Dickson [2], i.e. T and F are classes of R-modules such that (i) T is closed under taking submodules and quotients, (ii) F is closed under taking submodules, (iii) TCh F = (0}, and (iv) every R-module M contains a unique 33 34 L. FUCHS submodule TM C T with FM = M/TM C F. We say M is T-torsion or T-free according as TM = M or 0. A torsion theory is said to be finitely generated if every nonzero T-torsion module contains a cyclic submodule isomorphic to R/L where L is some finitely generated left ideal of R. Given a torsion theory, an exact sequence 0- • A- • B C- • 0 will be called T-exact if the induced sequenc
Book Reviews
No full textBook Review 1Book Title: Endocrinology of PregnancyBook Authors: F Fuchs & A Klopper (Eds.)Pp. x + 359. 12.50. New York: Harper & Row. 1970Book Review 2Book Title: Hyperbaric Oxygen and its Clinical ValueBook Author: N.G. MeijnePp. xx + 261. Geillustreerd. 16.50. Springfield, Ill.: Charles C. Thomas. 1970Book Review 3Book Title: Active/Passive. The crucial psychological dimensionsBook Author: E FriedPp. ix + 222. $7.95. New York and London: Grune & Stratton. 1970
Cello techniques and performing practices in the nineteenth and early twentieth centuries
No full textThis thesis comprises a study of cello performance practices throughout the nineteenth century and into the early decades of the twentieth. It is organised in terms of the increasing complexity of the concepts which it examines, as they are to be found in printed and manuscript music, instrumental methods and larger treatises, early recordings, concert reviews and pictures. Basic posture is considered along with different ways of holding the
bow. The development of the tail-pin shows that even when it was widely used, the older posture was still referred to as a model. Some implications for tone quality and tonal
projection are considered in the light of the shape of the arms. Some connections between the cellist's posture and that recommended by etiquette books are explored. The
functionality of the left hand and arm, and the development of modem scale fingerings, show that there was a considerable period of overlap between newer and older practices, with modern scale fingerings evolving over a long period of time. Similarly, views on the function of the right wrist in bowing are shown to change gradually, moving towards a more active upper arm movement with less extreme flexibility of the wrist. Two central expressive techniques especially associated with string playing arc considered in the context of the cello, namely vibrato and portamento. These topics are examined in the light of written indications in music, recommendations in cello treatises, and the practices evidenced in early recordings. The sources for this study can be brought into an overall
framework of a constant dialogue between `theory', as expressed in verbal instructions to the learner, or general a priori reflections about the cello, and `practice', manifested in performing editions and early recordings, or in individual acts of reception. A wide divergence is noted, both between theory and practice in general, and in terms of different styles of playing observable at any one time. It is suggested that tensions between practice
and critical disapproval can be resolved in terms of Lacanian discourse. Several test cases are used in order to compare several different recordings of the same works. The question of the musical character of the cello is discussed in terms of widespread assumptions about its gendered identity. A wide range of sources suggest that this moved from a straightforwardly `masculine' identity expressed through a controlling, elevated eloquence to a less clearly defined one, incorporating the 'feminine', with a greater stress on uninhibited emotional expression. Some performance implications for this change of view are pursued with respect to specific repertoires. Broad conclusions stress the importance of the diversity of performance practices as opposed to unifying generalisations
Callichroma collarti Fuchs 1959
No full text<i>Callichroma collarti</i> Fuchs, 1959, revalidated <p>(Figs 1–5)</p> <p> <i>Callichroma (s. str.) collarti</i> Fuchs, 1959: 2.</p> <p> <i>Callichroma collarti</i>; Damoiseau & Cools, 1987: 8 (types); Monné, 1993: 3 (cat.); Martínez, 2000: 86 (distr.); Monné, 2005: 26 (cat.).</p> <p> <i>Callichroma sericeum</i> (part); Napp & Martins, 2009: 329 (syn.).</p> <p> <i>Callichroma magnificum</i> Napp & Martins, 2009: 345; Monné <i>et al</i>., 2017: 6 (holotype); Taboada-Verona <i>et al</i>., 2017: 2; Monné, 2021: 39 (cat.). <i>Syn. nov.</i></p> <p> Fuchs (1959) described <i>Callichroma collarti</i> (Figs 3–5) as follows (translated): “Male. Frons irregularly, confusedly punctate, genae as long as the lower eye lobes, vertex and space between the antennal tubercles irregularly wrinkled and dense, finely punctate between the wrinkles, also with distinct median groove; area behind eyes rugose. The whole head, except for the black mandible apex, metallic green. Antennae black, more than twice as long as the body, the scape robust, irregularly wrinkled and punctate, with a depression in front of the end and a smaller one at the base; antennomeres III to X increasing in length, XI longer than IX and X together, III to XI carinate lengthways. Anterior margin of the pronotum projected forward centrally, posterior margin straight; lateral tubercles broadly conical, with blunt apex; in front of these, near the anterior margin, a transverse bulge on each side; pronotum constricted anteriorly and posteriorly; the whole surface transversely wrinkled, between the wrinkles and near the anterior margin very densely, finely punctate, lateral of prothorax and prosternum wrinkled; the whole prothorax metallic green, on both sides next to the midline of the pronotum between the wrinkles with more or less short, black pubescence. Scutellum triangular, very finely and densely punctate, with a smooth central longitudinal line, glabrous. Elytra narrowing backward and individually rounded at apex; covered with black-green pubescence, with a narrow, shiny metallic green sutural band, crosswise wrinkled; from the humerus to almost the apex there is a matt, metallic green longitudinal carina; the space between this carina and the side edge is slight lighter green than the space between the carina and the sutural band. Underside of the body shiny metallic green, smooth, with sparse punctures; prosternal process narrow, rounded; mesoventral process broader, flattened. Legs black, pro- and mesofemora, as well as the base half of the metafemora red; femora not punctate; the metafemora surpassing elytral apex, flattened on both sides. Female. Antennae slightly longer than the body, the antennomere XI slight longer than X (one of the females has completely black legs). Length; 28-36 mm. 3 males and 6 females from Muzo, Colombia, or Santa Fé de Bogotá, Colombia. (The 2 specimens from Sta. Fé de Bogotá carry a note: <i>Callichroma</i> nov. sp. Gounelle, 1911). Closest related to <i>Batesi</i> Gahan, but larger, stouter. <i>Batesi</i> has close to each side of the median line of the pronotum one black tomentose spot, the back of the head is only weakly punctate, the sides of the prothorax, the sloping part of the pronotum and the prosternum are smooth, and only the smooth midline of the pronotum and the shiny part immediately next to the black pubescent spots are wrinkled across; the areas under the black pubescent spots are extremely fine and tightly punctate. In addition, <i>Batesi</i> ’s ventral surface of the thorax and abdomen has short silver-white setae, while in the new species almost no setae can be seen.”</p> <p> According to Monné (2021) and Tavakilian & Chevillotte (2021): Holotype male: Colombia, Muzo (ISNB). However, as it is possible to see in the original description, there are syntypes, and not holotype and paratypes. Damoiseau & Cools (1987) reported: “ <b>collarti</b> FUCHS, 1959, Bull. Inst. r. Sci. nat. Belg. 35, 35: 2, 3, <b>Callichroma</b>. (*) [The etiquette of determination is handwritten by the author] / Type male, allotype female and paratype, (6), Colombie: Muzo, ex coll. Le Moult; Santa Fe De Bogota.” The mention of the specimens of the type series as holotype, allotype, and paratypes, even based on labels included by the author of the species but not mentioned in the original description, has no nomenclatural value (ICZN 1999: 72.1.1).</p> <p> Napp & Martins (2009) synonymized <i>C. collarti</i> with <i>C. sericeum</i> (Fabricius, 1793) (translated): “We could not find consistent morphological characters to distinguish <i>C. brachyale</i>, <i>C. gisteli</i>, and <i>C. collarti</i> (as well as the subspecies <i>rubricrus</i> of <i>C. gounellei</i>) from <i>C. sericeum</i> and we started to consider them as synonyms.” Apparently, Napp & Martins (2009) did not see photographs of the syntypes of <i>C. collarti</i>, which would make it evident that the two names do not correspond to the same species.</p> <p> <i>Cerambyx sericeus</i> (Fig. 6) has been reported as described by Fabricius (1793), and posteriorly mentioned by Olivier (1795). However, according to Fabricius (1793): “ <i>sericeus</i>. <i>Cerambyx</i> with thorax [prothorax] spined, entirely dark velvety, with elytral suture green, femora red. <i>Cerambyx sericeus</i>. Oliv. Ins. 67. tab. 5. Fig. 37. From Brazil, Museum of Dr. Olivier. Antennae not notably long, black. Head and thorax black, velvety, with distinct green macula [band]. Legs dark, femora red, the metafemora before middle. Metatibiae flattened. Olivier (1795) reported on <i>Cerambyx sericeus</i>: “Fab. Ent. Syst. emend. tom. I pars 2. pag. 253. nº 8.” Although the authorship and publication date are somewhat doubtful, the description in Fabricius (1793) and Olivier (1795), as well as the drawing in Olivier, do not allow having doubts about the mistake in the synonymy, especially by the pronotum densely pubescent in <i>Cerambyx sericeus</i>.</p> <p> Napp & Martins (2009) described <i>Callichroma magnificum</i> (Figs. 1–2) as follows (translated): “Male. Metallic green with cupreous reflections. Elytra only with metallic cupreous sutural band. Pro- and mesofemora red with peduncle and apex black. Metafemora black with red area near of the base. Antennae twice longer than the body length. Scape robust, with basal depression and apical projection; coarsely rugose-punctate. Antennomere III with distinct sulcus, as long as IV, and shorter than the following ones that have increasing lengths; XI at least 3 times the length of the III. Pronotum entirely striate; striae slender, smooth and distant between them; area between striae with punctures very fine and dense; pubescence not distinct. Striae of the pronotum extend over the lateral tubercles of the prothorax where they are weakest and with sparse punctures. Remaining surface of the sides of the prothorax smooth, shiny. Base shiny, not punctate, with some striae on anterior half and sides. Scutellum microrugose from base to near apex; pubescence not distinct; median sulcus smooth, more distinct on apical half; sulcus and apex of the scutellum cupreous. Sutural band of the elytra glabrous, rugose. On sides, depending on the angle of the light, appears to has a band (or line) very narrow, lighter, starting after the humerus and disappearing on apical third (almost indistinct). Pro- and mesofemora without basal sulcus; profemora with coarse punctures basally; mesofemora with very fine and shallow punctures on peduncle; metafemora opaque, flattened on entire length, without differentiated punctures, reaching the elytral apex. Metatibiae strongly flattened, sinuously expanded on apical half, as wide as the metafemora. Prosternum shiny with striae on entire surface (similar to the prothorax); procoxae surrounded on sides by striae; pubescence indistinct. Mesoventrite almost smooth, shiny. Metaventrite with sparse pubescence, with coarse, distinct punctures throughout. Ventrites shiny, almost smooth, with slight distinct pubescence. Apex of ventrite 6 truncate. Dimensions, mm, holotype male. Total length, 31.2; humeral width, 9.9. Type material. Holotype male, Colombia, Boyaca: Território Vazquez, II.1991, J. Urbina col. (MZSP).”</p> <p> The study of the original descriptions as well as examination of the holotype of <i>C. magnificum</i> and syntypes of <i>C. collarti</i> allowed concluding that the former is a junior synonym of the latter. Therefore, we are revalidating <i>Callichroma collarti</i>.</p> <p> In addition to the already mentioned chromatic variation, very common in American Callichromatini, the posterior area of the pronotum of <i>C. collarti</i> can be transversely striate or smooth.</p> <p> <b>Material examined.</b> COLOMBIA, <i>Boyacá</i>: Território Vasquez, holotype male of <i>C. magnificum</i>, II.1991, J. Urbina leg. (MZSP); Muzo, syntype female of <i>C. collarti</i>, ex coll. Le Moult [no more data] (HSCV). <i>Bogotá</i>: Santa Fé de Bogotá [Bogotá], syntype male of <i>C. collarti</i> [no more data] (HSCV).</p>Published as part of <i>Santos-Silva, Antonio & Schmid, Herbert, 2021, Revalidation, synonymies, and notes in American Callichromatini (Coleoptera Cerambycidae, Cerambycinae), pp. 579-586 in Zootaxa 5071 (4)</i> on pages 582-585, DOI: 10.11646/zootaxa.5071.4.6, <a href="http://zenodo.org/record/5726540">http://zenodo.org/record/5726540</a>
On the growth of solutions of second order complex differential equation with meromorphic coefficients
No full textWe consider the differential equation f'' + Af' + Bf = 0 where A(z) and B(z) a parts per thousand cent 0 are mero-morphic functions. Assume that A(z) belongs to the Edrei-Fuchs class and B(z) has a deficient value a, if f a parts per thousand cent 0 is a meromorphic solution of the equation, then f must have infinite order. Mathematical Subject Classification 2000: 34M10; 30D35.Mathematics, AppliedMathematicsSCI(E)1ARTICLEnul
The failure of organized religion in Laurence Sterne's Tristram Shandy
No full textThis thesis is an examination of Laurence Sterne's Tristram Shandy, in which the author shows that Sterne's fundamental concern with loneliness and mortality in Tristram significantly involves his belief that institutional religion--desiccated, corrupt, and ineffectual--is unable to help. Instead of providing strength, solace, inspiration, and communion, churches are decidedly human institutions comprised of the eccentric, the stupid, and the venal. Many references in the novel make it clear that religion--as Sterne sees it practiced by Anglicans and Catholics alike--is no remedy for one's loneliness or fear of death
The developmental morphology of Leea guineensis. I. Vegetative development
No full textPT: J; CR: FUCHS C, 1963, STAIN TECHNOL, V38, P141 GERRATH JM, 1990, BOT GAZ, V151, P210 GOULD KS, 1986, CAN J BOT, V64, P1268 HALLE F, 1978, TROPICAL TREES FORES LACROIX CR, 1989, AM J BOT, V76, P1203 MEICENHEIMER RD, 1983, CAN J BOT, V61, P3430 MERRILL EK, 1986, CAN J BOT, V64, P2650 NAIR NC, 1968, J INDIAN BOT SOC, V47, P193 POSTEK MT, 1982, AM J BOT, V69, P556 RIDSDALE CE, 1974, BLUMEA, V22, P57 ROHWEDER O, 1983, SAMENPFLANZEN MORPHO RUTISHAUSER R, 1985, BOTANISCHE JB SYSTEM, V107, P415 SATTLER R, 1974, PHYTOMORPHOLOGY, V24, P22 SATTLER R, 1988, AM J BOT, V75, P1606 SATTLER R, 1988, ASPECTS FLORAL DEV, P1 SUGIYAMA M, 1988, AM J BOT, V75, P1598 TOMLINSON PB, 1982, AXIOMS PRINCIPLES PL, P162 TOMLINSON PB, 1987, ANNU REV ECOL SYST, V18, P1 WILD H, 1966, FLORA ZAMBESIACA 2, V2, P492; NR: 19; TC: 4; J9: BOT GAZ; PG: 6; GA: DU901Source type: Electronic(1
Simultaneous Ultrasound Imaging Velocimetry (UIV) and Flow Visualization in Taylor-Couette flows: Validation of UIV in single-phase flows
No full textUltrasound Imaging Velocimetry (UIV) is applied to a Taylor-Couette flow, for the case of pure inner cylinder rotation. By imaging a radial-azimuthal plane, two velocity components are obtained simultaneously in a two-dimensional plane. For the single-phase flow studies, Iriodin flakes (commonly used for visualizing flow structures) are used as “flow tracers” for the backscatter of ultrasound. This allows for a simultaneous mapping of the flow regime, via flow visualization, as well as extracting quantitative velocity information in the radial gap. After validating UIV against the analytically well-defined laminar Circular Couette flow as well as turbulent Taylor-Couette flow, other regimes are probed as well, in particular, the Wavy Vortex flow. Finally, the application of UIV to a particle-laden Taylor-Couette flow (particle volume fraction, f_0:01) is considered, under the conditions of oscillatory pure inner cylinder rotation. The results presented here serve as a proof-of-concept for the application of UIV to the Taylor-Couette flow and will be applied to denser particle-laden flows (f _ 0:05) in the future.Multi Phase SystemsFluid Mechanic
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