241,456 research outputs found
Hf isotopic characteristics of the Tarim Permian large igneous province rocks of NW China: Implication for the magmatic source and evolution
No full textAbstract not availableZilong Li, Yinqi Li, Hanlin Chen, M. Santosh, Shufeng Yang, Yigang Xu, Charles H. Langmuir, Zhongxing Chen, Xing Yu, Siyuan Zo
Four new species of Lycocerus Gorham, 1889 from China (Coleoptera: Cantharidae)
No full textYang, Yu-Xia, Yang, Xing-Ke (2013): Four new species of Lycocerus Gorham, 1889 from China (Coleoptera: Cantharidae). Journal of Natural History 47 (1-2): 75-86, DOI: 10.1080/00222933.2012.742169, URL: http://dx.doi.org/10.1080/00222933.2012.74216
Alebroides spanner Yu & Yang, sp. nov.
No full textA. spanner Yu & Yang, sp. nov. Distribution. China (Guizhou).Published as part of Yu, Xiaofei & Yang, Maofa, 2014, Four new species of Alebroides Matsumura (Hemiptera: Cicadellidae: Typhlocybinae) from China, pp. 248-262 in Zootaxa 3780 (2) on page 252, DOI: 10.11646/zootaxa.3780.2.2, http://zenodo.org/record/23041
Alebroides strumae Yu & Yang, sp. nov.
No full textA. strumae Yu & Yang, sp. nov. Distribution. China (Tibet).Published as part of Yu, Xiaofei & Yang, Maofa, 2014, Four new species of Alebroides Matsumura (Hemiptera: Cicadellidae: Typhlocybinae) from China, pp. 248-262 in Zootaxa 3780 (2) on page 252, DOI: 10.11646/zootaxa.3780.2.2, http://zenodo.org/record/23041
Alebroides chiasmaticus Yu & Yang, sp. nov.
No full textA. chiasmaticus Yu & Yang, sp. nov. Distribution. China (Guangxi).Published as part of Yu, Xiaofei & Yang, Maofa, 2014, Four new species of Alebroides Matsumura (Hemiptera: Cicadellidae: Typhlocybinae) from China, pp. 248-262 in Zootaxa 3780 (2) on page 251, DOI: 10.11646/zootaxa.3780.2.2, http://zenodo.org/record/23041
Synonym, new species and checklist of the genus Fissocantharis Pic from Taiwan (Coleoptera, Cantharidae)
No full textYang, Yu-Xia, Okushima, Yûichi, Yang, Xing-Ke (2012): Synonym, new species and checklist of the genus Fissocantharis Pic from Taiwan (Coleoptera, Cantharidae). Zootaxa 3262: 46-53, DOI: 10.5281/zenodo.21303
A review of the Chinese species of Pseudopodabrus (Coleoptera: Cantharidae)
No full textYang, Yu-Xia, Kopetz, Andreas, Yang, Xing-Ke (2012): A review of the Chinese species of Pseudopodabrus (Coleoptera: Cantharidae). Acta Entomologica Musei Nationalis Pragae 52 (1): 217-228, DOI: http://doi.org/10.5281/zenodo.533006
Chao cai liao yong yu ya bo chang ju jiao: ge xiang yi xing hao sun cai liao yu ti du guang xue na mi bo dao guan
No full textKwok, Hui Kin = 超材料用於亞波長聚焦 : 各向異性耗損材料與梯度光學納米波導管 / 郭栩健.Thesis M.Phil. Chinese University of Hong Kong 2015.Includes bibliographical references (leaves 67-69).Abstracts also in Chinese.Title from PDF title page (viewed on 26, September, 2016).Kwok, Hui Kin = Chao cai liao yong yu ya bo chang ju jiao : ge xiang yi xing hao sun cai liao yu ti du guang xue na mi bo dao guan / Guo Xujian
Molecular mechanism of Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia based on network pharmacology, molecular docking, molecular dynamics simulations and experimental verification
No full textMycoplasma bovis pneumonia is a highly contagious respiratory infection caused by Mycoplasma bovis. It is particularly prevalent in calves, posing a significant threat to animal health and leading to substantial economic losses. Dang-Shen-Yu-Xing decoction is often used to treat this condition in veterinary clinics. It exhibits robust anti-inflammatory effects and can alleviate pulmonary fibrosis. However, its mechanism of action remains unclear. Therefore, this study aimed to preliminarily explore the molecular mechanism of Dang-Shen-Yu-Xing decoction for treating mycoplasma pneumonia in calves through a combination of network pharmacology, molecular docking, molecular dynamics simulation methods, and experimental validation. The active components and related targets of Dang-Shen-Yu-Xing decoction were extracted from several public databases. Additionally, complex interactions between drugs and targets were explored through network topology, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes enrichment analyses. Subsequently, the binding affinity of drug to disease-related targets was verified through molecular docking and molecular dynamics simulation. Finally, the pharmacodynamics were verified via animal experiments. The primary network topology analysis revealed two core targets and 10 key active components of Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia. Kyoto Encyclopedia of Genes and Genomes enrichment analysis showed that the mechanism of Dang-Shen-Yu-Xing decoction for treating mycoplasma bovis pneumonia involved multiple signaling pathways, with the main pathways including PI3K-Akt and IL17 signaling pathways. Moreover, molecular docking predicted the binding affinity and conformation of the core targets of Dang-Shen-Yu-Xing decoction, IL6, and IL10, with the associated main active ingredients. The results showed a strong binding of the active ingredients to the hub target. Further, molecular docking dynamics simulation revealed three key active components of IL10 induced by Dang-Shen-Yu-Xing decoction against Mycoplasma bovis pneumonia. Finally, animal experiments confirmed Dang-Shen-Yu-Xing decoction pharmacodynamics, suggesting that it holds potential as an alternative therapy for treating mycoplasma bovis pneumonia
The etiology of esophageal cancer in high- and low- risk areas of Jiangsu province, China
No full text [Background]Esophageal cancer (EC) remains one of the most common and fatal malignancies worldwide. The geographic variation in EC occurrence is striking, and China is an area with one of the highest incidences of EC. A number of epidemiological studies have been conducted toward EC in the past decades, results suggested that tobacco smoking, alcohol drinking, unhealthy dietary factors and chronic injuries of the esophageal mucosa are important in the development of this disease. Genetic polymorphisms in enzymes involved in metabolism of carcinogens may also influence individual susceptibility. However, the effects of major lifestyle and hereditary risk factors on the development of EC remain poorly understood in China. Moreover, little attention has been paid to the etiological heterogeneity between similar areas with great risk gradient. [Methods]From 2003 to 2007, a large population-based case-control study of EC has been conducted in a selected high-risk area and a selected low-risk area of Jiangsu Province, one of the highest cancer incidence areas in China. In total, 1,520 cases and 3,879 controls were recruited. In this thesis, we evaluated the role of major lifestyle factors such as tobacco smoking, alcohol drinking and dietary factors, as well as inherited determinants including family history of cancer and genetic polymorphisms of alcohol-metabolizing related genes on the risk of EC. In addition, we investigated how much of the risk gradient between two areas could be explained by variation in the distributions of major risk factors. [Results] Tobacco smoking and alcohol drinking moderately increased the risk of EC, while the positive associations were only found among men but not among women. Dietary factors were observed to play important roles in the development of EC. Specific dietary habits i.e., fast eating speed, and hot eating and/or drinking substantially elevated EC risk and could explain more than 20% of EC cases each. High intake of salty foods and fried foods, low consumption of raw garlic were also observed to increase the risk of EC. In addition to environmental and lifestyle factors, we confirmed that a positive family history can significantly increase EC risk, and found the inheritance may modify the effect of some unhealthy lifestyles. Moreover, we further explored the relationship between EC and single nucleotide polymorphismsof ADH1B, ADH1C and ALDH2 genes. Results showed that the slow metabolizing ADH1B G allele, ADH1C G allele and ALDH2 A allele significantly increased EC risk among moderate-to-heavy alcohol drinkers, and a significant interaction was observed between ALDH2 gene and alcohol consumption. Lastly, we found that more than 60% of EC cases could be attributable to major lifestyle risk factors in the study population; furthermore, dissimilar distribution of several lifestyle factors, together with variations of hereditary factors may be largely responsible for the incidence difference between two study areas. [Conclusion]The findings in this thesis confirm that unhealthy lifestyles including smoking, alcohol drinking and some dietary factors are the predominant risk factors of EC in China, and a large proportion of incidence difference between regions at varying risk could be attributed to the different prevalence of lifestyle factors. As most of the identified risk factors are modifiable, these could be translated into risk reduction prevention programs in China, and a substantial proportion of new EC cases are expected to be prevented by eliminating or avoiding these risk factors in the population. </p
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