235 research outputs found
FIGURE 1 in A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra
No full textFIGURE 1. Neocentrocnemis signoreti (Stål), 3. Habitus. Scale bar = 3.47 mm.Published as part of Li, Hu, Yan, Keyu, Constant, Jerome & Cai, Wanzhi, 2009, A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra, pp. 24-32 in Zootaxa 2166 on page 26, DOI: 10.5281/zenodo.18909
FIGURE 22 in A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra
No full textFIGURE 22. The distribution of Neocentrocnemis signoreti (Stål) () and Centrocnemoides sumatrana Miller ().Published as part of Li, Hu, Yan, Keyu, Constant, Jerome & Cai, Wanzhi, 2009, A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra, pp. 24-32 in Zootaxa 2166 on page 31, DOI: 10.5281/zenodo.18909
FIGURES 14–21. Centrocnemoides sumatrana Miller, 3. 14 in A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra
No full textFIGURES 14–21. Centrocnemoides sumatrana Miller, 3. 14, Head and pronotum, antennae removed; 15, paramere; 16, forewing (abnormal); 17, phallus; 18, 19, phallosoma; 20, pygophore; 21, apical part of abdomen. 14, 17, 20, lateral view; 18, 21 ventral view; 19, dorsal view. Scale bar of 14, 16, 21 = 1.25 mm; of 20 = 0.63 mm; of 15, 17–19 = 0.42 mm.Published as part of Li, Hu, Yan, Keyu, Constant, Jerome & Cai, Wanzhi, 2009, A review of the subfamily Centrocneminae (Hemiptera: Heteroptera: Reduviidae) from Sumatra, pp. 24-32 in Zootaxa 2166 on page 30, DOI: 10.5281/zenodo.18909
External Validation of the Population Pharmacokinetic Models of Amisulpride and Remedial Strategies for Delayed or Missed Doses
No full textDesheng Yan,1 Gehang Ju,2 Xin Liu,2 Qing Shao,1 Yan Zhang,3 Na Wang,1 Keyu Yan1 1Department of Pharmacy, Xi’an Mental Health Center, Xi’an, Shaanxi, 710100, People’s Republic of China; 2Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, 410000, People’s Republic of China; 3Xi’an Key Laboratory of Pharmacy (Mental Health), Xi’an Mental Health Center, Xi’an, Shaanxi, 710100, People’s Republic of ChinaCorrespondence: Keyu Yan, Xi’an Mental Health Center, Xi’an, Shaanxi, 710100, People’s Republic of China, Tel/Fax +86-18198010730, Email [email protected]: This study aimed to evaluate the predictive performance of published amisulpride population pharmacokinetic (PopPK) models in schizophrenia patients with an external data set and establish remedial dosing regimens for nonadherent amisulpride-treated patients.Methods: A systematic search was conducted on PubMed, Embase, and Web of Science to identify PopPK models for evaluation. The evaluation process involved analyzing 390 serum concentration samples obtained from 361 Chinese adult inpatients diagnosed with schizophrenia. Model predictability was evaluated by prediction-based and simulation-based diagnostics. Based on validation results, a modified PopPK model was constructed to characterize amisulpride pharmacokinetic in our patients. Monte Carlo simulation was employed to investigate non-adherence scenarios and the impact of subsequently administered remedial regimens.Results: In the five assessed published models, four included trough concentrations from schizophrenia patients, and one combined single-dose data from healthy older adults and trough concentrations from older adults with Alzheimer’s disease. The PE for population and individual predictions ranged from − 92.89% to 27.02% and − 24.82% to 4.04%, respectively. In the simulation-based diagnostics, the NPDE results indicated noticeable bias in all models. Therefore, a modified one-compartment model, with estimated creatinine clearance(eCLcr) as covariates on the apparent clearance (CL/F) of amisulpride, was developed. For delays in medication dosing, if the delay is within 12 hours, take half the missed dose right away, then resume the normal schedule; if the delay is up to 24 hours, just continue with the regular dosing schedule.Conclusion: Existing published models lack the necessary reliability for cross-center application. Future prospective studies are required to assess our model before integrating it into clinical practice. Model-based simulations provided a rational approach to propose remedial strategies for delayed or missed doses.Keywords: population pharmacokinetics, amisulpride, schizophrenia, external validation, adherenc
Raman spectroscopy for characterization of Fe/Al2O3 nanostructures
No full textIn this work, Raman spectroscope is used to characterize the Fe/Al2O3 catalysts to find the structure differences between different thicknesses of catalysts. These catalysts are used for carbon nanotube (CNT) growth in thermal chemical vapor deposition (CVD) method. In the previous CNT growth experiments, it is found that only certain thickness of catalyst has the best catalytic effect, but the reason is not very clear, so the objective of this dissertation is to characterize the structure differences between catalysts with different thickness to find the mechanism of catalytic effect in CNT growth.Master of Science (Precision Engineering
Reinterpreting and Remapping Philosophy, Evolutionism and Religion in Late Qing Missionary’s Translation of The Making of a Man
No full textBetween the Boxer Movement and the 1911 Revolution, missionaries in China confronted distinct social challenges compared to their counterparts in home countries. In response, American missionary Young John Allen and his Chinese assistant, Van Yi, co-translated James Wideman Lee’s The Making of a Man into Chinese as Ren Xue. This translation aimed to counter Spencer’s social evolutionism, introduced by native intellectuals like Yan Fu, offering a reinterpretation of the relationships among individuals, nations, and God. Additionally, it sought to remap philosophy, evolutionism, ethics, and religion tailored for late Qing China. In contrast to clergymen in America and China, Chinese native intellectuals developed their unique reinterpretations and reshaping of philosophy, science, evolutionism, ethics, and religion for China. Through a cross-comparison of works by Yan Fu, Huxley, Spencer, Lee and Allen, this study explored the diverse responses to Spencer’s evolutionary theory and related issues among the advocates of evolutionism, Chinese intellectuals, and clergies in America and China
Pore Structure Characterization of Eocene Low-Permeability Sandstones via Fractal Analysis and Machine Learning: An Example from the Dongying Depression, Bohai Bay Basin, China
No full textStudy on the possibility of compensation for moral damages for breach of contract
No full textThe purpose of this article is to explore the possibility of establishing a system of moral damages for breach of contract through the study of tourism contracts, so as to protect the interests of contractual counterparties who suffer non-pecuniary losses as a result of non-serious damages. The current state of affairs is that, in general, for breach of contract, current scholarship and general doctrine is strongly opposed to the inclusion of moral damages in the system of damages for breach of contract, and instead insists on a dualistic system of remedies for breach of contract and tort. The shortcomings of this approach are that tort damages and breach of contract damages have different principles of proof and imputation, and the standard of damages cannot be claimed without reaching a certain standard, making it impossible for the interests of the right holder to be adequately remedied. This article will examine the case law and comparative approach to the possibility of moral damages for pure contractual breaches that have not yet resulted in serious damage, and thus to develop a vision for the establishment of such a system. The establishment of such a system will provide a higher degree of protection for the interests of the contractual counterparty and thus achieve a full remedy of rights
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