116 research outputs found
Electron microscopic, immunofluorescent and virological studies on a rhabdomyosarcoma in epidermodysplasia verruciformis
No full textA subcutaneous tumor of a patient with epidermodysplasia verruciformis
was studied by the light microscopy, the electronmicroscopy and
the immunofluorescent test. The tumor cells were histologically pleomorphic
and electronmicroscopically contained varying amounts of cytoplasmic filaments without Z-band formation. The antimyosin serum stained the tumor cells, showing their myogenic origin. No virus or virus-like particles were observed in the tumor. Tumor antigens stainable by the
patient's serum were not detected. Hamsters inoculated with the tumor extract at birth developed no noticeable diseases.</p
A Physiological Aspect of the Citric Acid Cycle of Micrococcus pyogenes var. aureus (Terashima)
No full textIn 1957, Yabe reported that the combined administration of glutamate and glucose markedly accelerated the respiration of Micrococcus pyogenes var. aureus (Terashima) over the sum of those in each of the two substrates, and that this phenomenon was due to the important role of glutamate as a sole sparker or entering site of the citric acid cycle of M. pyogenes var. aureus (Terashima). In the present experiments, the authors investigated this phenomenon in regard to pH. In the presence of glutamate and glucose, oxygen consumption or carbon dioxide evolution was nearly the same at all pHs tested, whereas ammonia formation was the best at pH 6.2, which was the optimum for glutamate oxidation by M. pyogenes var. aureus (Terashima); this result seems to sustain the conclusion given by Yabe. For all of glutamate, aspartate and alanine, the oxidation optimum pHs were lower in M. pyogenes var. aureus (Terashima) than in pyogenes var. albus and citreus. From thsee results, it is easily inferred that the cytoplasmic membrane of M. pyogenes var. aureus (Terashima) is a pretty peculiar one compared with those of the other two micrococci, and that these peculiar physiological properties of the cytoplasmic membrane have something to do with the previously reported peculiar aspect of the citric acid cycle of M. pyogenes var. aureus (Terashima)
Mori Yoshiro: Man and Politician
No full textThe article is devoted to life and activities of Mori Yoshiro, one of the most distinguished and colorful politicians of contemporary Japan. The article addresses Yoshiro’s childhood and youth years, when his interest to sport was revealed, and, first of all, to rugby. This, in many aspects, assisted the formation of his views on relations between people. Considerable attention is devoted to the role of Yoshiro’s father in his education, to the influence of his precepts on his life choice, to the basic guidelines of his political philosophy. For forty-three years Mori, as a Member of Parliament, was in the center of political life in Japan. Fourteen times he was a winner in the election to the highest legislative body of Japan. He occupied the leading posts in the Liberal Democratic party, and once was the head of the Cabinet. He is known as a proponent of active Japan-Russian relations and a supporter of a compromise-based solution of the territorial problem. Upon retirement from political career, he plays a big role in Japan’s public life. Since 2014, he is the Chairman of the Tokyo Organising Committee of the Olympic and Paralympic Games of 2020. The author focuses on the achievements and difficulties in Mori’s life way
El Tlacuache Núm. 930 (2020). 930 Año 19 (2020) abril. El Tlacuache
No full text- Retos y perspectivas de la siembra de aguacate de Hueyapan por María Alejandra E. Olvera Carbajal. - Xochicalco: miradas actuales desde la comunidad por Ollin Yoliztli Martínez Mendoza, Brisa Katzuyo Mejía Yoshiro, Arantxa Rodríguez Ortiz, Guadalupe Gómez Velasco y Alejandra Figueroa Celito
Request for certificate
No full textEnglish translation of the certificate. The original certificate in Japanese is found in item: csudh_tsu_0012. This certificate was requested by Tsugitada Kanamori, addressed to Nakao Ito, the Mayor of Yokohama City Naka Ward, to certify that Yoshiro Okubo is a welfare commissioner at Bojyo-kai Fifth District. Nakao Ito certifies that the information provided, namely that Yoshiro Okubo is a welfare commissioner, is confirmed. The translator is Henry Tanisaki, Manager, Japan Chemical Service.This collection contains one box of documents belonging to Tsugitada Kanamori. Materials in this collection mostly pertain to Kanamori’s efforts regarding canceling his renunciation and reinstating his American citizenship
Attempts to isolate virus from human brain tumors
No full textIn order to study the viral etiology of human brain
tumors, attempts were made to isolate cytopathogenic agents from human brain tumors by the tissue culture of tumor tissues and by the mixed culture of tumor tissues with HeLa cells. Five glioblastomas, a mixed form of glioblastoma and fibrosarcoma, two astrocytomas, two ependymomas, two meningiomas, an oligodendroglioma, a spongioblastoma polare and a choroid plexus papilloma were studied. In the tissue culture, besides the cells which appeared to be the tumor parenchymal cells, varying amounts of fibroblastic cells appeared in all the tumors tested and they increased with the prolongation of the
culture period. In any of the tumors tested, no cytopathogenic agents were detected by either the culture of tumor tissues or the mixed culture of tumor tissues with HeLa cells. From the virological point of view, the significance of these negative results was discussed.</p
Attempts to isolate virus from human brain tumors
No full textIn order to study the viral etiology of human brain
tumors, attempts were made to isolate cytopathogenic agents from human brain tumors by the tissue culture of tumor tissues and by the mixed culture of tumor tissues with HeLa cells. Five glioblastomas, a mixed form of glioblastoma and fibrosarcoma, two astrocytomas, two ependymomas, two meningiomas, an oligodendroglioma, a spongioblastoma polare and a choroid plexus papilloma were studied. In the tissue culture, besides the cells which appeared to be the tumor parenchymal cells, varying amounts of fibroblastic cells appeared in all the tumors tested and they increased with the prolongation of the
culture period. In any of the tumors tested, no cytopathogenic agents were detected by either the culture of tumor tissues or the mixed culture of tumor tissues with HeLa cells. From the virological point of view, the significance of these negative results was discussed.</p
The Virus Of Epidermodysplasia Verruciformis: Electron Microscopic And Fluorescent Antibody Studies
No full textFive cases of epidermodysplasia verruciformis were studied for viral particles and antigens. In all benign lesions tested, viral particles and antigens were observed by electron microscopy of ultrathin sections and/or tissue extracts and by fluorescent antibody staining with an antiserum against human wart virus. Both viral particles and antigens were observed in the cells of the stratum corneum and not in those of deeper layers. Viral particles and antigens were observed in nuclei. Viral particles resembled morphologically the virus of common human warts. In two, one on the forehead and the other on the inner aspect of the upper thigh, of six lesions showing the histology of early malignancy, viral particles were observed by electron microscopy of ultrathin sections and/or tissue extracts. Four advanced malignant lesions, two primary ulcerated squamous cell carcinomas and two recurrent carcinomas, were similarly studied. In none of them, were viral particles or antigens detected. These results suggest that (1) the virus of epidermodysplasia verruciformis is related with that of common human warts both morphologically and antigenically, (2) at least some of the virus-induced lesions of epidermodysplasia verruciformis become malignant, and (3) when the lesions are completely replaced with malignant cells, neither viral particles nor antigens are recognizable in them
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