10,798 research outputs found

    RDLS-SS-DWT v. 0.9

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    This fileset contains the implementation of RDLS-DWT and SS-DWT in JPEG 2000 (RDLS-SS-DWT v. 0.9), which was used in a research described in: R. Starosolski, “Application of reversible denoising and lifting steps to DWT in lossless JPEG 2000 for improved bitrates,” Signal Processing: Image Communication, Vol. 39, Part A, pp. 249-63, DOI: 10.1016/j.image.2015.09.013, 2015 and R. Starosolski, “Skipping selected steps of DWT computation in lossless JPEG 2000 for improved bitrates,” submitted.   This software is intended for research purposes only; it is provided "as is"; author makes no warranty of any kind, either express or implied, with respect to this software. <br

    Sensor Selection with Composite Features for Human-Prosthetic Interfaces (SS-CF)

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    Matlab implementation of the sensor selection algorithm presented in paper: T. Yu, A. Mohammadi, Y. Tan, P. Choong and D. Oetomo, "Sensor Selection With Composite Features in Identifying User-Intended Poses for Human-Prosthetic Interfaces," in IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 31, pp. 1732-1742, 2023, doi: 10.1109/TNSRE.2023.3258225Quick Start:Run Main_SSCF.m for an example.Dataset:Dataset: dataset.mat contains one non-disabled subject performing forward reaching to spatial target points with their upper limb.The goal is to select q sensors that can best differentiate the three elbow poses required by the spatial target points.Upper limb and upper body joint kinematics and sEMG signals are recorded with features extracted.The full dataset of 10 subjects is available at: https://doi.org/10.26188/23294693.Citation:We would appreciate your acknowledgement by citing the paper:@article{Yu2023,author={Yu, Tianshi and Mohammadi, Alireza and Tan, Ying and Choong, Peter and Oetomo, Denny},journal={IEEE Transactions on Neural Systems and Rehabilitation Engineering}, title={Sensor Selection With Composite Features in Identifying User-Intended Poses for Human-Prosthetic Interfaces}, year={2023},volume={31},pages={1732-1742},doi={10.1109/TNSRE.2023.3258225}}For more details and updates please check: https://github.com/tianshi-yu/SS-CF_Sensor_Selection_with_Composite_Features</p

    Reduction-Responsive Nanoparticles Self-Assembled from Sericin-ss-Doxorubicin Conjugate for Hydrophobic IR780 Delivery with Integration of Antitumor Chemo-Phototherapy

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    Lulu Zhang,1 Haiyang Liu,1 Jin Ren,2 Junyi Shao,1 Yanrong Cao,1 Shuangshuang Wang,1 Changchun Peng,3 Shengwen Shao,1,2 Haixia Ge,1 Jingmou Yu1,2 1Huzhou Key Laboratory of Medical and Environmental Applications Technologies, School of Life Sciences, Huzhou University, Huzhou, People’s Republic of China; 2Jiangxi Provincial Key Laboratory of Cell Precision Therapy, School of Basic Medical Sciences, Jiujiang University, Jiujiang, 332005, People’s Republic of China; 3Jiangxi Jimin Kexin Pharmaceutical Co., Ltd., Yichun, 332000, People’s Republic of ChinaCorrespondence: Haixia Ge, Email [email protected] Jingmou Yu, Email [email protected]: Stimuli-responsive polymer-drug nanoparticles have emerged as a versatile and effective platform for delivering drugs in the treatment of malignant tumors. The integration of chemo-phototherapy has gained increasing prominence due to its remarkable synergistic antitumor effects.Methods: Hydrophilic sericin (Ser) was linked to antitumor drug doxorubicin (DOX) via a disulfide bond. The obtained Ser-ss-DOX conjugate was characterized by Fourier-transform infrared spectroscopy (FTIR), proton nuclear magnetic resonance (1H NMR) and dynamic light scattering (DLS). The near-infrared (NIR) fluorescent dye IR780 was encapsulated into Ser-ss-DOX by a dialysis method. The physical state of IR780 within Ser-ss-DOX/IR780 nanoparticles was analyzed by differential scanning calorimetry (DSC). The photothermal properties and drug release behavior of IR780-loaded nanoparticles were systematically investigated. Cellular uptake and reactive oxygen species (ROS) generation capacity and in vitro cytotoxicity of IR780-containing nanoparticles were studied in 4T1 breast cancer cells. In addition, 3D multicellular tumor spheroid model was conducted to investigate the antitumor activity of the nanoparticles.Results: The Ser-ss-DOX conjugate was successfully synthesized. Ser-ss-DOX and Ser-ss-DOX/IR780 nanoparticles were spherical in shape, and their particle sizes measured by DLS were 326 and 190 nm, respectively. IR780 was in an amorphous state within the Ser-ss-DOX/IR780 nanoparticles. The loading contents of DOX and IR780 were 8.26% and 2.78%, respectively. Ser-ss-DOX/IR780 exhibited ideal photothermal properties in vitro and reduction-sensitive drug release in a high glutathione (GSH) environment. Ser-ss-DOX/IR780 displayed higher cellular uptake in 4T1 cells than Ser-ss-DOX and free DOX. Under 808 nm laser irradiation, Ser-ss-DOX/IR780 showed a strong capacity to generate ROS. Importantly, Ser-ss-DOX/IR780 with laser irradiation effectively inhibited the growth of 4T1 cells and 3D multicellular tumor spheroids.Conclusion: This work demonstrated that Ser-ss-DOX/IR780 integrated dual functionalities of chemotherapy and phototherapy, thereby enabling substantial potential for application in tumor treatment. Keywords: polymeric nanoparticles, doxorubicin, sericin, IR780, chemo-phototherap

    A hybrid particle Swann optimization algorithm for optimal task assignment in distributed systems

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    [[abstract]]In a distributed system, a number of application tasks may need to be assigned to different processors such that the system cost is minimized and the constraints with limited resource are satisfied. Most of the existing formulations for this problem have been found to be NP-complete, and thus finding the exact solutions is computationally intractable for large-scaled problems. This paper presents a hybrid particle swarm optimization algorithm for finding the near optimal task assignment with reasonable time. The experimental results manifest that the proposed method is more effective and efficient than a genetic algorithm. Also, our method converges at a fast rate and is suited to large-scaled task assignment problems. (c) 2005 Elsevier B.V. All rights reserved.[[note]]SC

    SS Northland Echo

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    Photograph - A view of the steamboat, SS Northland Echo on the Athabasca River. Athabasca, Albert

    SS Athabasca River - 02

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    Photograph - A view of the SS Athabasca River paddle steamer on the river, Athabasca, Albert
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