869 research outputs found
Comparison of the Accuracy and Time Efficiency of Two Different digital Impressions of Single Tooth Implant Treatments
No full textObjective: Over the last decades, techniques and materials have evolved with the improvement in digital technology. Computer-aided impressions have been transforming the dental implant field with these developments. The aim of this in vivo study was to compare the accuracy and time efficiency between two intraoral scanning systems in single tooth implant treatment. Methods: 10 patients with single tooth bone level implant (Straumann, Basel, Switzerland) received one conventional impression with polyvinyl siloxane and three scans with 2 different intra-oral scanners (CEREC AC Omnicam and Straumann CARES IOS). The time required for the impressions was measured at this stage. The casts obtained from conventional impressions were scanned as the master model to evaluate accuracy. Digital impression files were analyzed using a software (Geomagic Control). Independent Samples Test was performed for trueness and precision. One-way ANOVA was executed for time efficiency. Least significant difference test for post hoc comparison was conducted (p<0.05). Results: The differences between the two systems regarding trueness and precision were not statistically significant (P>0.05), but a statistically significant difference was found in the time efficiency (P<0.05). CEREC AC showed the lowest mean values in time measures. Conclusions: There was no difference regarding accuracy in comparison between CEREC AC Omnicam and CARES. CEREC AC Omnicam was found to be superior in terms of time efficiency in comparison to CARES and conventional impressions
Retrospective Analysis of Lithium Disilicate Laminate Veneers Applied by Experienced Dentists: 10-Year Results
No full textPurpose: To report on the 10-year clinical treatment outcomes for a strictly applied clinical protocol for pressable lithium disilicate glass-ceramic laminate veneers (LDLVs) placed by two experienced dentists. Materials and Methods: A 10-year follow-up assessment of 364 LDLVs placed in 41 patients was undertaken with the clinical criteria color/esthetic match of the porcelain surface, chipping and fracture occurrence, marginal discoloration, and integrity, assessed using the modified United States Public Health Service scoring system. Results: After 10 years, the survival rate was 97.4%. Complications occurred in 1.64% of the restorations (fractures and debonding in 0.55% and 1.09%, respectively). Conclusion: A strict, repeatable protocol for placing veneers with experienced dentists yielded good results
Clinical performance of pressable glass-ceramic veneers after 5, 10, 15, and 20 years: A retrospective case series study
No full textObjectives To evaluate the long-term clinical performance and survival rate of pressable lithium-disilicate glass-ceramic veneers (LDSVs). Materials and Methods A total of 413 LDSVs were bonded to anterior and posterior teeth by three experienced clinicians between 1998 and 2012. The LDSVs were examined for color/ esthetic match of the glass-ceramic surface (esthetic evaluation), fracture rate, marginal discoloration (staining of the luting cement), and marginal integrity (including caries, clinical evaluation). For clinical and esthetic evaluations, the modified United States Public Health Services (USPHS) score was used in this study. The success rate was determined with a Kaplan-Meier survival analysis. Results The mean observation time was 11.33 +/- 4.85 years. There was no loss to follow-up, all restorations were accounted for in the final analysis. The probability of survival of the 413 veneers was 98% after 5 years, 95% at 10 years, 91% at 15, and 87% at 20 years, indicating a very low clinical failure rate. Of the 413 restorations, complications were occurred in 15 (3.63%) of all restorations, and fractures and debonding in 6 (1.45%) and 9 (2.18%), respectively. Conclusions The LDSVs showed high survival rate and very good results for color match and anatomic form and marginal integrity in the long-term analysis. Clinical Significance The long-term performance of LDSVs can be considered as highly favorable when carefully planned
The Clinical and Radiologic Outcomes of Early Loaded Implants After 5 Years of Service
No full textPurpose: To evaluate the 5-year results of the clinical and radiographic outcomes of three types of early loaded implants. Materials and Methods: Seventy-five implants were placed in the posterior mandible or maxilla in 30 patients. Three types of implants (Straumann SLActive, Astra OsseoSpeed, and Thommen Implant System) were used. Definitive restorations were made after 8 weeks of implant placement. The radiographs were taken at the placement of the prosthesis, at 6 months, and at 1- and 5-year follow-ups. Clinical and radiologic data were evaluated for all types of implants. The Wilcoxon signed rank test, least significant differences, and Mann-Whitney U were used to test for statistically significant differences (P < .005). Results: Twenty-four patients and 62 implants were evaluated after 5 years. The mean marginal bone loss was 0.20 +/- 0.40 mm, 0.21 +/- 0.05 mm, and 0.25 +/- 0.36 mm after 1 year and 0.32 +/- 0.22 mm, 0.31 +/- 0.26 mm, and 0.42 +/- 0.36 mm after 5 years for the Straumann, Astra, and Thommen groups, respectively. After 5 years, the mean peri-implant probing depth level was 1.75 +/- 0.49 mm, 1.87 +/- 0.48 mm, and 1.92 +/- 0.57 mm for the Straumann, Astra, and Thommen groups, respectively. No peri-implantitis was detected after 5 years of loading. Conclusion: All groups of implants showed a stable peri-implant probing depth and marginal bone level. The survival rate was high and bone loss was low at 5 years; thus, early loading may be a useful procedure that allows reduction in treatment time
Two-body wear of occlusal splint materials against different antagonists
No full textBackground This study aimed to demonstrate that the material of the occlusal splint can be chosen according to the needs of individual patients and contribute to the knowledge of the wear rate of these materials. Methods In this study, four occlusal splint materials (Sr Ivocap Heat Cured, Valplast, SR Ivocap Elastomer and Eclipse) and three antagonists (natural tooth enamel, inCoris TZI and IPS e.max Press ceramic materials) were used. Each wear test was performed using a chewing simulator (n = 16; test load: 50 N; number of cycles: 10,000, 20,000 and 30,000; continuous rinsing with water at 30 degrees C for the wet condition). The Shapiro Wilk test was used for normal distribution suitability. Antagonist on average wear quantities both main effects and interactions of material, cycle and condition factors were investigated by Univariate variance analysis. Multiple comparisons were examined using the Games-Howell test. Results There was a statistically significant effect of the difference in materials on the amount of wear (p < 0.001). Furthermore, there was a statistically significant difference among the mean values of all materials (p > 0.001). The highest mean value was obtained with Eclipse (0,318 mu m(3)), and the lowest mean value was obtained with Valplast (0,134 mu m(3)). Conclusion Our study found differences in the in vitro wear rate among various occlusal splint materials
Fracture Resistance of Porcelain Laminate Veneers
No full textIn recent dentistry, laminate veneers have gained widespread utilization as a conservative treatment option of unaesthetic anterior teeth. The continued development of dental ceramics offers clinicians many options for creating highly aesthetic and functional porcelain veneers. The behavior of these restorations against the functional loads plays an important role in their success. Many studies have evaluated the fracture resistance of laminate veneers in vitro and in vivo
Clinical and Radiographic Evaluation of Early Loaded Maxillary Anterior Implants: Three-Year Follow-up
No full textThe aim of this study was to evaluate clinical and radiologic results up to 3 years in patients treated with early loading of anterior implants supporting single-tooth all-ceramic restorations. Twenty-four patients were treated with 29 screw-type implants in the anterior maxilla. The implants were evaluated by clinical and radiographic parameters. Clinical parameters Plaque Index (PI), Sulcus Bleeding Index (BI), peri-implant probing depth (PD), and marginal bone loss (MBL) were recorded. At the recall examinations, all implants were successfully integrated, demonstrating healthy peri-implant soft tissues as documented by standard clinical parameters. No biologic complications were observed. There was no statistically significant increase in MBL between the baseline and recall stages (P >.05). Early loaded maxillary anterior implants supporting single-tooth restorations reveal successful clinical and radiographic outcomes when treatment steps were performed
Tüm dişleri mevcut hastalarda konvansiyonel ölçü ve intraoral dijital taramanın netliğinin karşılaştırılması
No full textBackground: Over the last years, different intraoral scanningsystems for direct digitalization have been introduced to the dentalmarket. However, the accuracy of these scanners is variable, andlittle information is available. The aim of this in vivo study was tocompare the accuracy of two intraoral scanning systems and thedifference between upper and lower jaw on the accuracy.Methods: 10 patients with full dentition received one conventionalimpression with polyvinyl siloxane (Elite HD+, Zhermack SpA, Italy)and three scans with CEREC OC (Sirona Dental Systems, Sirona,Bensheim, Germany) and Straumann CARES IOS (Intra oralScanner, Basel, Switzerland) for upper and lower jaw. Theconventional impressions were poured and the casts made from itwere scanned and used as the reference model to evaluateprecision and trueness of intraoral scanning virtual modelsprovided by each system. Digital models were analyzed with asoftware (Geomagic Control; Geomagic, Morrisville, USA).Results: The trueness value was 99.88±42.56 μm in upper jaw and82.6±26.81 μm in lower jaw for CEREC OC, and 105.53±25.49 μmin upper jaw, and 109.56±36.84 μm in lower jaw for CARES IOS.The differences between these two systems were not statisticallysignificant (P>0.05), but statistically significant difference wasfound in the precision (P<0.05). CEREC OC showed higher valuein both upper and lower jaws.Conclusion: CEREC OC was more precise than CARES IOS andat a similar level of trueness. No statistically significant differencewas found between upper and lower jaws in both systemsAmaç: Son senelerde, direkt dijitalizasyon için farklı intraoral_x000D_
tarama sistemleri ortaya çıkmıştır. Ancak bu tarayıcılarının_x000D_
doğruluğu değişkendir ve hakkındaki bilgiler yetersizdir. Bu_x000D_
çalışmanın amacı, iki farklı intraoral tarama sisteminin, alt ve üst_x000D_
çene arasındaki tarama doğruluğu farkının karşılaştırılmasıdır._x000D_
Gereç ve Yöntemler: 10 adet tam dişli hastanın her birinden bir_x000D_
adet PVS (Elite HD+, Zhermack SpA, İtalya) materyali ile ölçü_x000D_
alındı ve 3 adet alt-üst çene taraması CEREC OC(Sirona Dental_x000D_
Systems, Sirona, Bensheim, Almanya) ve Straumann CARES IOS_x000D_
(Intra oral Scanner, Basel, İsviçre) ile yapıldı. Konvansiyonel_x000D_
ölçüden elde edilen alçı modeller taratılarak referans model olarak_x000D_
netlik ve doğruluk kıyaslamasında kullanıldı. Netlik_x000D_
değerlendirilmesindeki deviasyonlar diğer ölçülerin birbiri üzerine_x000D_
çakıştırılması metodu ile gözlemlendi. Dijital ölçü dosyaları STL_x000D_
formatına dönüştürülerek (Geomagic Control; 3D Systems. ABD)_x000D_
işlendi ve analiz edildi._x000D_
Bulgular: Doğruluk değerleri, CEREC OC için üst çenede_x000D_
99.88±42.56 μm alt çenede, 82.6±26.81 μm dir. CARES IOS için_x000D_
üst çene doğruluk değeri 105.53±25.49 μm, alt çene doğruluk_x000D_
değeri 109.56±36.84 μm dur. İki sistem arasındaki doğruluk_x000D_
değeri farkı istatistiksel olarak anlamlı değildir (P>0.05). Netliğin_x000D_
farkı istatiksel olarak anlamlıdır (P<0.05), CEREC OC alt ve üst_x000D_
çenede netlik açısından daha yüksek değerler gösterdi._x000D_
Sonuç: CEREC OC netlik olarak CARES IOS sisteminden daha_x000D_
üstün bulunurken, doğruluk seviyesi her iki sistemde de benzerdir._x000D_
Alt ve üst çeneler arasında her iki sistemde istatistiksel olarak_x000D_
anlamlı fark bulunmamıştır
An Overview of Lenalidomide in Combination with Rituximab for the Treatment of Adult Patients with Follicular Lymphoma: The Evidence to Date
No full textUmut Yilmaz, Ayse Salihoglu, Teoman Soysal Division of Hematology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, TurkeyCorrespondence: Umut YilmazIstanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Hematology, Fatih, Istanbul, TurkeyTel +90 541 797 76 47Email [email protected]: Follicular lymphoma (FL) is an indolent (low-grade) malignancy of B cells and is among the most common hematological cancers affecting adults. Its clinical presentation, natural course, and severity are highly variable. Management of FL depends on the clinical setting; most patients require multiple lines of treatment. Chemoimmunotherapy is the standard of care for FL patients needing treatment; however, alternative treatments are limited for refractory patients or those unfit for chemoimmunotherapy. Multiple alternatives to chemoimmunotherapy for FL are being developed, with some showing significant promise. Lenalidomide combination with rituximab (LR) is among the most successful and extensively studied novel approaches. LR has been compared head-to-head in clinical trials with rituximab monotherapy and chemoimmunotherapy in the frontline and to lenalidomide or rituximab monotherapy in the relapsed or refractory setting for the treatment of FL. Initial reports of these nine trials have been published in the last decade, and their long-term data will be available in the coming years. LR offered superior efficacy to either lenalidomide or rituximab monotherapy alone. The RELEVANCE trial compared the efficacy of LR with chemoimmunotherapy among 1030 FL patients and demonstrated similar efficacy with a different side effect profile. Myelosuppression, rash, and fatigue were among the significant adverse events. Most patients treated with LR received thromboprophylaxis. This paper aims to summarize and comment on the published evidence regarding LR treatment for FL through a literature review. The clinical trials will be presented in detail, and methodological differences complicating their comparisons will be discussed.Keywords: rituximab, lenalidomide, follicular lymphoma, chemo-free, R
Lamina veneer preparasyon derinliklerinin 3B sistemler ile değerlendirilmes
No full textBackground: Preparation depth of laminate veneers are essential inretention and structural integrity of restorations. The aim of this studywas to evaluate the difference between a trained professionalprosthodontist (PP) and a postgraduate prosthodontics student (PPS)in the preparation depth of laminate veneers by scanning the toothwith a 3D scanner before and after the preparation.Methods: Twenty extracted human maxillary central incisors wereevaluated by a PP and PPS. A 0.5 mm depth guide bur was used infor facial reduction and a 1 mm incisal reduction was performed witha deep chamfer. The teeth were scanned with a laser scanner at anaccuracy of 10 µm. The teeth were separated into 3 parts (incisal,middle and cervical) and then 5 points were randomly selected on theunprepared tooth and then lapped over when the preparation hadbeen completed. The data of the difference was calculated in 3Dscanning software Magics (Materialise NV, Belgium). Statisticalanalysis were performed with one-way ANOVA (p < 0.05).Results: PP results showed mean values in the Incisal of0.328+0.045 mm, Middle of 0.375+0.097 mm and Cervical of0.471+0.07 mm. PPS results showed mean values in the Incisal of0.323+0.056 mm, Middle results of 0.403+0.083 mm and Cervicalresults of 0.462+0.075 mm.Conclusion: These results suggest that a PP or a PPS can bothachieve the same precision in the preparation using a depth guidebur.Amaç: Lamina veneer restorasyonlarında preparasyon derinliği,_x000D_
yapısal sağlamlığın ve tutuculuğun sağlanmasında temel_x000D_
faktörlerin başında gelir. Bu çalışmanın amacı, deneyimli bir_x000D_
prostodontist (PP) ve yüksek lisans protodonti öğrencisinin_x000D_
(PPS) lamina preparasyon derinliklerinin, preparasyon_x000D_
öncesinde ve sonrasında 3B tarayıcı ile farklılıklarının_x000D_
değerlendirilmesidir._x000D_
Gereç ve yöntemler: PP ve PPS 20 adet çekilmiş insan_x000D_
maksiller santral kesiciyi değerlendirmiştir. Fasiyel preparasyon_x000D_
için 0,5 mm’lik derinlik rehberli frez kullanılmıştır. İnsizal_x000D_
preparasyon için ise 1 mm’lik champher frez kullanılmıştır._x000D_
Dişler, 10 µm hassasiyetinde lazer tarayıcı ile taranmıştır. Dişler_x000D_
3 kısıma (insizal, orta ve servikal) bölünmüş ve 5 noktadan_x000D_
incelenmiştir. Preparasyon yapılmamış ve yapılmış dişler üst_x000D_
üste çakıştırılarak Magics (Materialise NV, Belgium) 3B tarama_x000D_
yazılımında aralarındaki farklar incelenmiştir. İstatistiksel analiz_x000D_
tek yünlü ANOVA ile yapılmıştır (p < 0.05)._x000D_
Bulgular: PP sonuçları ortalama insizalde 0.328+0.045 mm,_x000D_
ortada 0.375+0.097 mm, servikalde ise 0.471+0.07 mm_x000D_
olurken, PPS sonuçları ortalama insizalde 0.323+0.056 mm,_x000D_
ortada 0.403+0.083 mm ve servikalde 0.462+0.075 mm olarak_x000D_
bulunmuştur._x000D_
Sonuç: Bu sonuçlar, derinlik belirleyici frez kullanıldığında PP ve_x000D_
PPS benzer preparasyon hassasiyet gösterdiğini belirtmektedir
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