52,436 research outputs found
Absorption enhancement using nanoneedle array for solar cell
No full textA theoretical analysis of light trapping properties of Gallium arsenide (GaAs) nanoneedle arrays(NNAs) solar cells is presented. The effect of geometric parameters on the optical absorption of NNAs has been analyzed by using rigorous coupled wave analysis algorithm and finite element method. Compared with nanowire arrays and thin-film layer counterpart, higher light absorption efficiency can be achieved in GaAs NNAs, due to the graded refractive index of NNAs that incident light can be coupled into the NNAs efficiently. The absorption profiles at different wavelength and angle-dependant optical properties of NNAs are also evaluated. Meanwhile, the short-circuit current of GaAs NNAs for various lengths at fixed filling factor is obtained
Eukaryotic Plankton Species Diversity and Community Structure in Xiao Jiang River (the primary tributary of Upper Yangtze River), Yunnan
No full text Eukaryotic Plankton Species Diversity and Community Structure in Xiao Jiang River (the primary tributary of Upper Yangtze River), Yunnan </p
ACR878362 Supplemental Material - Supplemental material for Diffusional kurtosis imaging of kidneys in patients with hyperuricemia: initial study
No full textSupplemental material, ACR878362 Supplemental Material for Diffusional kurtosis imaging of kidneys in patients with hyperuricemia: initial study by Zhong-Yuan Cheng, You-Zhen Feng, Xiao-Ling Liu, Yao-Jiang Ye, Jun-Jiao Hu and Xiang-Ran Cai in Acta Radiologica</p
Understanding the Support Needs and Challenges Faced by Family Caregivers in the Care of Their Older Adults at Home [Letter]
No full textZhanshuo Xiao,1 Yilin Jiang,2 Narina A Samah2 1Department of Dermatology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 2School of Education, Universiti Teknologi Malaysia, Skudai, Johor, 81310, MalaysiaCorrespondence: Yilin Jiang; Zhanshuo Xiao, Email [email protected]; [email protected]
Building Resilience: A Qualitative Analysis of Bullying Among Children with Disabilities on Parental and Teacher’s Perspective [Letter]
No full textZhanshuo Xiao,1,* Yilin Jiang,2,* Narina A Samah2 1Department of Dermatology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 2School of Education, Universiti Teknologi Malaysia, Skudai, Johor, 81310, Malaysia*These authors contributed equally to this workCorrespondence: Yilin Jiang; Zhanshuo Xiao, Email [email protected]; [email protected]
Motivation and Barriers to Postoperative Rehabilitation Exercise in Type 2 Diabetic Patients with Rotator Cuff Injuries: A Qualitative Study [Letter]
No full textZhanshuo Xiao,1,* Yilin Jiang,2,* Narina A Samah2 1Department of Dermatology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 2School of Education, Universiti Teknologi Malaysia, Skudai, Johor, 81310, Malaysia*These authors contributed equally to this workCorrespondence: Yilin Jiang; Zhanshuo Xiao, Email [email protected]; [email protected]
The inhibitory effects of Xiao-Gao-Jiang-Zhuo-containing serum on adipogenesis in 3T3-L1 preadipocytes
No full textBackground. Obesity and related metabolic diseases are becoming a worldwide epidemic, leading to increased mortality and heavy medical costs. Our Chinese herbal formula Xiao-Gao-Jiang-Zhuo (XGJZ) has remarkable effects on curing obese patients in the clinic, but the cellular and molecular basis remains unknown. This study aimed to reveal the molecular mechanism involved in adipogenesis in vitro. Methods. Chinese herbal formula XGJZ-containing serum was prepared from XGJZ-treated obesity model rats. The function of XGJZ-containing serum was validated in 3T3-L1 preadipocytes. Oil O staining was performed to determine intracellular lipid accumulation in differentiated 3T3-L1 cells. The expression of pro-adipogenic transcription factors was measured to further validate the adipogenesis of 3T3-L1 adipocytes. The contents of triglyceride (TG), free fatty acid (FFA), and glycerin, along with the activities of lipid metabolism-related enzymes (including FAT, FATP1, DGAT, GPAT, ATGL, and HSL) were measured to study the lipogenesis in 3T3-L1 adipocytes. Results. XGJZ-containing serum inhibited 3T3-L1 differentiation, decreased intracellular lipid accumulation, and suppressed the expression of pro-adipogenic transcription factors in differentiated 3T3-L1 cells. The contents of TG, FFA, and glycerin were decreased when treated with XGJZ-containing serum, which also modulated lipid metabolism-related enzyme activities. The activities of fatty acid transporters (FAT, FATP1) and lipid mobilization enzymes (ATGL, HSL) were promoted, while activities of triglyceride biosynthesis enzymes (DGAT, GPAT) were attenuated in differentiated 3T3-L1 cells. Conclusion. XGJZ-containing serum has inhibitory effects on adipogenesis in 3T3-L1 preadipocytes, affirming the effect of XGJZ in treating obesity. It provides evidence for the mechanism of obesity
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