7,009 research outputs found
Computational protocol for the identification of X-linked genes contributing to X chromosome upregulation from RNA-sequencing datasets
No full textSummary: The X chromosome/autosome ratio has been widely used to profile XCU at the chromosomal level. However, this approach overlooks features of inside genes. Here, we present a computational protocol for the identification of X-linked genes contributing to X chromosome upregulation from RNA-sequencing datasets. We describe steps for selecting data, preparing software, processing data, and data analysis. This protocol quantifies the contribution value and contribution increment of each X-linked gene to XCU.For complete details on the use and execution of this protocol, please refer to Lyu et al. (2022).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics
CUHK electronic theses & dissertations collection
No full textLyu, Kai.Thesis Ph.D. Chinese University of Hong Kong 2015.Includes bibliographical references (leaves 498-539).Abstracts also in Chinese.Title from PDF title page (viewed on 06, December, 2016)
CUHK electronic theses & dissertations collection
No full textLyu, Chen.Thesis Ph.D. Chinese University of Hong Kong 2014.Includes bibliographical references (leaves 148-159).Abstracts also in Chinese.Title from PDF title page (viewed on 04, October, 2016)
Environmental cost and impacts of chemicals used in agriculture: An integration of emergy and Life Cycle Assessment
No full textModern intensive agriculture worldwide is generating increasing environmental pressure, which prevents its sustainable development. A number of agricultural sustainability assessment approaches and methodological frameworks have been developed by research worldwide to assess the environmental costs and impacts of resources used in agricultural production. A joint use of Life Cycle Assessment (LCA, to assess a process' performance and environmental impacts) and Emergy Accounting (EMA, to estimate environmental support to resource generation and provision) is proposed in this study. The goal is not only to ascertain the environmental ‘cost’ of production of selected chemical resources used in agricultural processes, but also to develop a reliable calculation procedure capable to integrate the two approaches (LCA and EMA), while considering their different allocation algebra and space-time scales of application. Specifically, the UEVs of glyphosate and urea, which are respectively the most used herbicide and nitrogen fertilizer used in worldwide agriculture, are calculated, yielding values of 2.47E+13 sej/kg and 7.07E+12 sej/kg, respectively. In order to do so, UEVs of intermediate process chemicals such as ammonia, acetic anhydride, chlorine gas, formaldehyde, phosphorous chloride, and sodium hydroxide have also been calculated or updated, thus providing at the same time a procedure and a set of values potentially useful for future studies. The LCA impacts of agro-chemicals in China are compared to worldwide averages from the Ecoinvent database, and the UEVs for several chemicals are also compared to previous estimates from published emergy literature
Design, construction, and control of curves and surfaces via deployable mechanisms
No full textThere has been an increasing interest in design and construction of deployable mechanisms (DMs) with multiple degrees of freedom (DOFs). This paper summarizes a family of deployable mechanisms that approximates a series of curves and surfaces using the polygonal approximation technique. These mechanisms are obtained by linking the two- and three-dimensional deployable units, which are constitutive of Sarrus and scissor linkages. Multiple unit mechanisms with varying sizes are assembled and alter their shape within a different family of parameterized curves and surfaces. A systematic methodology for polygonal approximation method is presented. Quadratic, semi-cubic, cubic, quartic and sextic curve boundaries, and quadric surfaces are approximated and controlled. Computer-aided design (CAD) models and kinematic simulations elucidate the mechanism's ability to approximate a set of curves and surfaces
Appendix_1,_2_and_3 – Supplemental material for Analyzing the Economic Sustainability of Tourism Development: Evidence from Hong Kong
No full textSupplemental material, Appendix_1,_2_and_3 for Analyzing the Economic Sustainability of Tourism Development: Evidence from Hong Kong by Hanqin Qiu, Daisy X. F. Fan, Jiaying Lyu, Pearl M. C. Lin and Carson L. Jenkins in Journal of Hospitality & Tourism Research</p
An integrative conservation and management strategy based on biological and cultural diversity assessment: A case study of Miaoling mountainous region, China
No full textThe Miaoling mountainous region, a typical karst landscape in Southwest China, is rich in biological resources and possesses an indigenous cultural heritage. However, ecological degradation and the encroachment of external cultures present significant threats to these areas, creating dual challenges to their biological and cultural integrity. To effectively protect the bio-cultural features in the Miaoling region, this study proposes a strategy for establishing a conservation framework based on the evaluation of bio-cultural diversity for protection. First, the four indicators of biodiversity and five indicators of cultural diversity were used to assess the value of bio-cultural diversity. Next, the Zonation model was integrated to identify priority zones. Finally, using these priority zones, a ’source − corridor − network’ strategy was developed. The results have revealed that nearly half of the region exhibits a lack of coordination between bio-cultural diversity. The priority conservation zones for bio-cultural diversity, which cover a total area of 2,286.76 km2, are located within small watershed and agroforestry ecosystems, displaying a fragmented distribution. Also, the conservation network encompasses 29 primary corridors, 76 secondary corridors, and 25 nodes. Based on that, a multi-stakeholder adaptive management framework has been proposed, emphasizing policy and financial support, community participation, and collaboration to integrate ecological protection with sustainable development. This study highlights the potential of bio-cultural diversity assessments in identifying priority zones and guiding strategic conservation planning in the karst mountainous regions
Towards Operational Cost Minimization in Hybrid Clouds for Dynamic Resource Provisioning with Delay-Aware Optimization
No full textRecently, hybrid cloud computing paradigm has be widely advocated as a promising solution for Software-as-a-Service (SaaS) providers to effectively handle the dynamic user requests. With such a paradigm, the SaaS providers can extend their local services into the public clouds seamlessly so that the dynamic user request workload to a SaaS can be elegantly processed with both the local servers and the rented computing capacity in the public cloud. However, although it is suggested that a hybrid cloud may save cost compared with building a powerful private cloud, considerable renting cost and communication cost are still introduced in such a paradigm. How to optimize such operational cost becomes one major concern for the SaaS providers to adopt the hybrid cloud computing paradigm. However, this critical problem remains unanswered in the current state of the art. In this paper, we focus on optimizing the operational cost for the hybrid cloud paradigm by theoretically analyzing the problem with a Lyapunov optimization framework. This allows us to design an online dynamic provision algorithm. In this way, our approach can address the real-world challenges where no a priori information of public cloud renting prices is available and the future probability distribution of user requests is unknown. We then conduct extensive experimental study based on a set of real-world data, and the results confirm that our algorithm can work effectively in reducing the operational cost
X-ray patterns for new compound K2BaCa(PO4)2
No full text<p>X-ray patterns for new compound K2BaCa(PO4)2</p>
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