30,343 research outputs found
The Equalization of Factor Prices in General Equilibrium When Commodities Out-Number Factors
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Production experiences and market structure in R&D competition
No full textIn the R&D race the incumbent enjoys an advantage of learning from production
experiences, but this important feature has not been incorporated into existing studies.
Assuming that the technological knowledge is accumulated not only by R&D expenditures but
also by production experiences, we study the properties of optimal investment strategies in a
model with an incumbent & many identical challengers. After proving the existence of a
unique Nash equilibrium in the R&D race, we demonstrate analytically that the likelihood of
persistent leadership increases with production experiences of the incumbent but decreases
with the number of challengers. Numerical analyses also establish that (i) the challengers
always invest more than the incumbent & the difference increases with production
experiences, the flow of monopoly profits & the number of challengers; & (ii) the
likelihood of persistent leadership increases with the value of being the winner & the value of being a loser but decreases with expected waiting time of R&D innovation & the flow of
monopoly profits. However, destructive innovations may still occur even when production
experiences are allowed to play an important role in the R&D competition
robust template matching using multiview video for head modeling
No full textrobust template matching using multiview video for head modeling. fu-che wu. murphy chien-chang ho. ming ouhyoung. department of computer science & information engineering. national taiwan universit
Wen re zhui yan
No full textv.1. 三家醫案合刻 / 葉桂著 -- v.2. 三家醫案合刻 / 繆遵義著 -- 三家醫案合刻 / 薛雪著 -- v.3. 附刊書札 / 陸增 -- v.3-5. 醫效秘傳 : 三卷 / 吳金壽校 -- v.6. 温熱贅言 / 寄瓢子述 ; 天倪室道人校.v.1. San jia yi an he ke / Ye Gui zhu -- v.2. San jia yi an he ke / Mou Zunyi zhu -- San jia yi an he ke / Xue Xue zhu -- v.3. Fu kan shu zha / Lu Zeng -- v.3-5. Yi xiao mi zhuan : san juan / Wu Jinshou jiao -- v.6. Wen re zhui yan / Jipiaozi shu ; Tiannishidaoren jiao.葉桂著 ; 繆遵義著 ; 薛雪著; 吳金壽纂. 醫效秘傳 : 三卷 / 吳金壽校. 温熱贅言 / 寄瓢子述 ; 天倪室道人校.綫裝.框15.2x10.9公分, 8行21字. 白口, 左右雙邊, 單黑魚尾. 版心上鐫題名, 下鐫葉次.刻書年據例言.內封背頁牌記鐫"笠澤吳子音氏彙纂"三卷《三家醫案合刻》分別為葉桂, 繆遵義, 薛雪所著. 吳金壽例言云纂輯刻書事.《中國中醫古籍總目》11421著錄.鈐"莊兆祥印"朱, 白文各一方.Xian zhuang.Kuang 15.2 x 10.9 gong fen, 8 hang 21 zi. Bai kou, zuo you shuang bian, dan hei yu wei. Ban xin shang juan ti ming, xia juan ye ci.Ke shu nian ju li yan.Nei feng bei ye pai ji juan "Lize Wu Ziyin shi hui zuan"Detailed notes in vernacular field only.Detailed notes in vernacular field only.Ye Gui zhu ; Mou Zunyi zhu ; Xue Xue zhu; Wu Jinshou zuan. Yi xiao mi chuan : san juan / Wu Jinshou jiao. Wen re zhui yan / Jipiaozi shu ; Tiannishidaoren jiao.Qian "Zhuang Zhaoxiang yin" zhu, bai wen ge yi fang
HO-1 is a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy
No full textChun-Nan Yeh,1 Ren-Chin Wu,2 Chi-Tung Cheng,1 Chun-Yi Tsai,1 Yau-Ren Chang,1 Ta-Sen Yeh,1 Tsung-Han Wu,1 Wei-Chen Lee,1 Kun-Chun Chiang3 1Department of Surgery, Liver Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 333, Taiwan; 2Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 333, Taiwan; 3General Surgery Department, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan Background: More than 500,000 people suffered from hepatocelluar carcinoma (HCC) annually and the relative incidence to mortality rate indicates its unfavorable prognosis. Several studies have proved that heme-oxygenase-1 (HO-1) is indirectly engaged in the invasion and the metastasis of some types of malignancies, including breast cancer, prostate cancer, and lung cancer. The role of HO-1 in hepatitis B virus (HBV)-related HCC is still not clarified.Materials and methods: The Western blot, doubling time, cell cycle analysis, migration assay, invasion assay, gene transfection, xenograft animal model, immunohistochemistry staining, and clinical validation study were applied in this study.Results: HO-1 overexpression not only decreased the growth but also inhibited the migration and invasion in human HBV-HCC cells (Hep-3B vs PLC/PRF/5 ). The inhibitory effect on growth, migration, and invasion is further demonstrated by the overexpression of HO-1 in Hep-3B cell by transfection study. Furthermore, HO-1 decreasing the growth of HBV-HCC was confirmed in animal study. The clinical validation illustrated that higher HO1 expression was also associated with favorable disease-free survival of HBV-HCC patients who underwent hepatectomy.Conclusions: We identified HO-1 as a favorable prognostic factor for HBV-HCC patients who underwent hepatectomy. Keywords: HO-1, HBV, HCC, hepatectom
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