5,624 research outputs found

    Bioactivities of HP-β-CD/cinnamaldehyde complex

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    [[abstract]]Cinnamaldehyde has been used frequently in medical treatment, some researches indicated that Cinnamaldehyde can use as antimicrobial and antifungal. There are two main goals in our study. One is to characterize Cinnamaldehyde’s ability to inhibit tyrosinase, the other is to screen it’s antibacterial activity. We encapsulated Cinnamaldehyde through hydroxypropyl-β-cyclodextrin (hp-β-CD) by molecular inclusion, and the resulting Cinnamaldehyde complex could release it’s content with time. Furthermore, the results of antibacterial test also demonstrated that the activity of Cinnamaldehyde against Gram-positive bacteria were related to the content of Cinnamaldehyde complex. The formations of hp-β-CD Cinnamaldehyde complex were characterized by differential canning calorimetry (DSC), thermo-gravimetric analysis (TGA), TLC ,UV , NMR. The minimum inhibitory concentration (MIC) of Cinnamaldehyde complex defined as the lowest concentration is able to inhibit visible microbial growth, and minimum bactericidal concentration (MBC) is the lowest concentration of needed to kill of the bacteria. Both MIC and MBC were determined by using the broth serial dilution method and plating on agar. According to our results, hp-β-CD Cinnamaldehyde complex is a strongly tyrosinase inhibitor and useful for antibacterial, demonstrating that hp-β-CD Cinnamaldehyde complex exhibits good propert ies and potential on treating clinical treatment

    The Impact of strategic implementation on the employees and contractors of the Hewlett-Packard Company.

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    Conducted within the global corporation of the Hewlett-Packard Company, (HP),this research examines employee and contractor responses to strategic implementation. The research environment is a relatively small UK group withinthe corporation that has continuously experienced significant change as new strategies were implemented. Employee and contractor responses to three separate cycles of change are analysed together with data drawn from the wider corporation by using a psychological contract framework, semi-structured interviewing, a research diary and secondary data from the literature and electronic sources. The research is essentially qualitative but draws on quantitative data where appropriate. A case study approach within an action research paradigm is the chosen methodology to allow consideration and triangulation of multiple sources of data relevant to the natural workplace setting. The research has confirmed a change from old or original psychological contracts to new contracts where employees and contractors are more insecure in, and more cynical of, their employment. This change is perceived as a violation of their psychological contract and is causing employees and contractors to adopt a more mercenary approach to their employment with HP. The special bond between HP and its employees generated by the values and egalitarian working environment created by its founders has been broken by new leadership. Acquisition of the Compaq Computer Company has further impacted employees and contractors resulting in declining morale and increasing scepticism about its proposed benefits. Indeed the very legitimacy of the acquisition and the leadership of HP are being questioned as HP changes to a new form. According to the founders, the values established that made HP successful in its first fifty years were expected to continue for at least another fifty years. This research shows how changing these values has collectively impacted employees and contractors resulting in a major threat to the continuing existence of HP in its present form

    IMMEDIATE CA (CUSTOMER ADVISORY) NOTIFICATION MECHANISM

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    EA/CA document on web to inform end user what’s critical issue they may encounter and how to work‐around or avoid it. However, the read rate by end user is quite low and still cause lots of service calls, worst is to return unit to raise HP repair cost. We proposed In‐Time CA method to check customer’s unit ID and show them latest security hole message/critical issue status and where to get solution. Through Capsule interface to trigger Critical WU to immediately inform customer urgent info they best to know while their system is connected to the network
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