2,618 research outputs found
sj-pdf-1-ang-10.1177_00033197211072598 - Supplemental Material for Comprehensive Meta-Analysis of Functional and Structural Markers of Subclinical Atherosclerosis in Women with Polycystic Ovary Syndrome
No full textSupplemental Material, sj-pdf-1-ang-10.1177_00033197211072598 for Comprehensive Meta-Analysis of Functional and Structural Markers of Subclinical Atherosclerosis in Women with Polycystic Ovary Syndrome by Dandan Sun, Yupeng Wu, Mingyan Ding, and Fang Zhu in Angiology</p
Temperate forest elevational gradient: spatial variation and deterministic processes in soil oribatid mite community assembly
No full text<p>The data sets were analyzed during the current study. Data from: Temperate forest elevational gradient: spatial variation and deterministic processes in soil oribatid mite community assembly.</p>
sj-docx-1-jet-10.1177_15266028231209236 – Supplemental material for A Systematic Review and Meta-analysis of Atherectomy Plus Balloon Angioplasty Versus Balloon Angioplasty Alone for Infrapopliteal Arterial Disease
No full textSupplemental material, sj-docx-1-jet-10.1177_15266028231209236 for A Systematic Review and Meta-analysis of Atherectomy Plus Balloon Angioplasty Versus Balloon Angioplasty Alone for Infrapopliteal Arterial Disease by Haichao Wu, Dandan Zheng, Long Zhou, Qiang Wang, Tao Wang and Siyuan Liang in Journal of Endovascular Therapy</p
sj-docx-1-cll-10.1177_09636897221124485 – Supplemental material for Identification of Immune Infiltration and Effective Immune Biomarkers in Acute Lung Injury by Bioinformatics Analysis
No full textSupplemental material, sj-docx-1-cll-10.1177_09636897221124485 for Identification of Immune Infiltration and Effective Immune Biomarkers in Acute Lung Injury by Bioinformatics Analysis by Dandan Ling, Xiang Zhang, Jiamin Wu, Qianyun Xu, Zhiyong He and Jun Zhang in Cell Transplantation</p
sj-pdf-1-imr-10.1177_03000605211032855 - Supplemental material for Anesthetic management of thoracoscopic pulmonary wedge resection with a giant tracheal diverticulum in the carina: a case report and review of the literature
No full textSupplemental material, sj-pdf-1-imr-10.1177_03000605211032855 for Anesthetic management of thoracoscopic pulmonary wedge resection with a giant tracheal diverticulum in the carina: a case report and review of the literature by Xiao Huang, Yuan Sun, Dandan Lin, Changewi Wei, Anshi Wu and Chao Gao in Journal of International Medical Research</p
Reduced-complexity non-coherent soft-decision-aided DAPSK dispensing with channel estimation
No full textDifferential Amplitude Phase Shift Keying (DAPSK), which is also known as star-shaped QAM has implementational advantages not only due to dispensing with channel estimation, but also as a benefit of its low signal detection complexity. It is widely recognized that separately detecting the amplitude and the phase of a received DAPSK symbol exhibits a lower complexity than jointly detecting the two terms. However, since the amplitude and the phase of a DAPSK symbol are affected by the correlated magnitude fading and phase-rotations, detecting the two terms completely independently results in a performance loss, which is especially significant for soft-decision-aided DAPSK detectors relying on multiple receive antennas. Therefore, in this contribution, we propose a new soft-decision-aided DAPSK detection method, which achieves the optimum DAPSK detection capability at a substantially reduced detection complexity. More specifically, we link each a priori soft input bit to a specific part of the channel's output, so that only a reduced subset of the DAPSK constellation points has to be evaluated by the soft DAPSK detector. Our simulation results demonstrate that the proposed soft DAPSK detector exhibits a lower detection complexity than that of independently detecting the amplitude and the phase, while the optimal performance of DAPSK detection is retained
sj-pdf-1-eji-10.1177_20587392211059362 – Supplemental Material for Wnt/β-catenin signaling regulates lipopolysaccharide-altered polarizations of RAW264.7 cells and alveolar macrophages in mouse lungs
No full textSupplemental Material, sj-pdf-1-eji-10.1177_20587392211059362 for Wnt/β-catenin signaling regulates lipopolysaccharide-altered polarizations of RAW264.7 cells and alveolar macrophages in mouse lungs by Jiali Yang, Ying Wang, Dandan Yang, Jia Ma, Shuang Wu, Qian Cai, Jing Xue, Chao Yuan, Jing Wang and Xiaoming Liu in European Journal of Inflammation</p
Loss of Sirt6 in adipocytes impairs the ability of adipose tissue to adapt to intermittent fasting
No full textIntermittent fasting (IF) is gaining popularity for its effectiveness in improving overall health, including its effectiveness in achieving weight loss and euglycemia. The molecular mechanisms of IF, however, are not well understood. This study investigated the relationship between adipocyte sirtuin 6 (Sirt6) and the metabolic benefits of IF. Adipocyte-specific Sirt6-knockout (aS6KO) mice and wild-type littermates were fed a high-fat diet (HFD) ad libitum for four weeks and then subjected to 12 weeks on a 2:1 IF regimen consisting of two days of feeding followed by one day of fasting. Compared with wild-type mice, aS6KO mice subjected to HFD + IF exhibited a diminished response, as reflected by their glucose and insulin intolerance, reduced energy expenditure and adipose tissue browning, and increased inflammation of white adipose tissue. Sirt6 deficiency in hepatocytes or in myeloid cells did not impair adaptation to IF. Finally, the results indicated that the impaired adipose tissue browning and reduced expression of UCP1 in aS6KO mice were accompanied by downregulation of p38 MAPK/ATF2 signaling. Our findings indicate that Sirt6 in adipocytes is critical to obtaining the improved glucose metabolism and metabolic profiles conferred by IF and that maintaining high levels of Sirt6 in adipocytes may mimic the health benefits of IF. Fat metabolism: facilitating responses to intermittent fasting The health benefits of intermittent fasting regimens are mediated in part by a protein 'switch' that modulates metabolic and inflammatory activity in fatty tissue. Several studies have linked such dietary regimens, which entail alternating periods of fasting and eating, to improved metabolic health. Researchers led by Byung-Hyun Park and Eun Ju Bae at Chonbuk National University, Jeonju, South Korea, have now demonstrated that the sirtuin 6 protein coordinates important physiological changes in response to such diets. The researchers noted that intermittent fasting mitigated the effects of a high-fat diet in control mice. In contrast, mice lacking sirtuin 6 in their fat cells exhibited features of metabolic syndrome under these conditions, including active inflammation in fatty tissue and reduced response to insulin. These results suggest that therapies that modulate sirtuin 6 could mirror the benefits achieved through intermittent fasting.
Clinical significance of cytokeratin 19 fragment in COVID-19 patients: a retrospective study
No full textBackground: Cytokeratin 19 fragment (CYFRA 21-1) is an important biomarker of lung cancer. There are clinical observations of elevated serum levels of lung cancer biomarkers in patients with viral pneumonia. However, the clinical significance of CYFRA 21-1 in coronavirus disease 2019 pneumonia has not been investigated. Methods: This retrospective study included 252 patients with community-acquired pneumonia (CAP) between December 1, 2022, and September 30, 2023. They were classified into three groups by clinical diagnosis and severity, namely mild non-COVID-19 CAP (n = 86), mild COVID-19 (n = 100), and severe COVID-19 (n = 66). Demographic characteristics, history, outcomes, and laboratory tests, including CYFRA 21-1 levels, were collected and compared among the groups. Risk factors associated with the diagnosis of COVID-19 pneumonia and severity were explored using appropriate statistical methods. Results: CYFRA 21-1 levels progressively increased from mild non–COVID-19 CAP to mild COVID-19 and severe COVID-19. Lower lymphocyte and platelet counts, alongside elevated CYFRA 21-1 levels, were associated with COVID-19 pneumonia. Multivariate analysis identified CYFRA 21-1 as an independent diagnostic [diagnosis odds ratio (OR) = 2.369; 95% confidence interval (CI) = 1.638–3.605; p < 0.001] and prognosis factor of COVID-19 pneumonia (severity OR = 1.416; 95% CI = 1.119–1.867; p = 0.01). The area under the receiver operating characteristic curve of CYFRA 21-1 for predicting the development of severe COVID-19 pneumonia was 0.913. Spearman analysis showed a negative correlation between CYFRA 21-1 levels and oxygenation index, with a correlation coefficient of −0.278 (p = 0.024). Conclusion: CYFRA 21-1 may be a potential diagnostic and prognostic indicator of COVID-19 pneumonia. Prospective multicenter studies are needed to confirm its clinical value.</p
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