18,708 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
Full text linkThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Schlumberger’s Nähgarn, Bestes für Hand- & Maschinenarbeit, Ch. Bahy Mühlhausen
No full textSCHLUMBERGER’S NÄHGARN, BESTES FÜR HAND- & MASCHINENARBEIT, CH. BAHY MÜHLHAUSEN
Schlumberger’s Nähgarn, Bestes für Hand- & Maschinenarbeit, Ch. Bahy Mühlhausen ( -
The bovine immune milk from hyperimmunized cows inhibits airway hyperresponsiveness and airway allergic inflammation of OVA-sensitized BALB/c mice
No full textDenkmal König Ludwig II. 1864 - 1886, München, Verlag: Ch. Reinhardt, München
No full textDENKMAL KÖNIG LUDWIG II. 1864 - 1886, MÜNCHEN, VERLAG: CH. REINHARDT, MÜNCHEN
Denkmal König Ludwig II. 1864 - 1886, München, Verlag: Ch. Reinhardt, München ( -
Electronic phase separation and the CMR effect in Pr1-xCaxMnO3 films on (001) vicinal SrTiO3 substrates
No full textOur previous work showed that Pr1-xCaxMnO3 (x=0.2-0.5) thin films reveal an electronic phase separation, in which the low-temperature phase is orbital- and charge-ordered of the Zener-polaron type [Ch. Jooss, T. Beetz, L. Wu, M. Beleggia, R. Klie, M. Schofield, Y. Zhu, S. Schramm, J. Hoffmann, submitted for publication]. Applying a magnetic field leads to a ferromagnetic and conducting phase, which gives rise to the colossal magneto resistance effect (CMR). In this article we show that the orbital- and charge-ordered state could be significantly modified by different kind of lattice defects. Quenched disorder, present after the film deposition, can suppress long-range ordering. In addition, extended defects like twin boundaries act as a nucleation center for ordered domains, i.e. the hysteretic properties depend on the density of these defects. Well-ordered artificial anti-phase boundaries (APB) can be introduced by an epitaxial growth on vicinal substrates, leading to anisotropic transport properties with respect to the orientation of the APB. (C) 2007 Elsevier B.V. All rights reserved
Surface ultrastructure and mechanical property of human chondrocyte revealed by atomic force microscopy.
No full textWerkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Werkzeuge mit obiger Schutzmarke, Ch. Bahy Mühlhausen
No full textWERKZEUG-FABRIK MUTZIG-FRAMONT, MUTZIG I.E., MAN VERLANGE ÜBERALL DIE WERKZEUGE MIT OBIGER SCHUTZMARKE, CH. BAHY MÜHLHAUSEN
Werkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Werkzeuge mit obiger Schutzmarke, Ch. Bahy Mühlhausen ( -
Werkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Werkzeuge mit obiger Schutzmarke, Ch. Bahy Mühlhausen
No full textWERKZEUG-FABRIK MUTZIG-FRAMONT, MUTZIG I.E., MAN VERLANGE ÜBERALL DIE WERKZEUGE MIT OBIGER SCHUTZMARKE, CH. BAHY MÜHLHAUSEN
Werkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Werkzeuge mit obiger Schutzmarke, Ch. Bahy Mühlhausen ( -
Werkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Kaffeemühlen mit obiger Schutzmarke, Ch. Bahy Mühlhausen
No full textWERKZEUG-FABRIK MUTZIG-FRAMONT, MUTZIG I.E., MAN VERLANGE ÜBERALL DIE KAFFEEMÜHLEN MIT OBIGER SCHUTZMARKE, CH. BAHY MÜHLHAUSEN
Werkzeug-Fabrik Mutzig-Framont, Mutzig i.E., Man verlange überall die Kaffeemühlen mit obiger Schutzmarke, Ch. Bahy Mühlhausen ( -
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