27,680 research outputs found
Catholic Comments Podcast.
Wendy M. Wright and David McPherson discuss the connection between philosophy and “the good life.”
McPherson teaches philosophy at Creighton University
David Smith Interview
An interview with David Smith of Eagle Car Dealership in Morehead, Kentucky by Christian Wright discussing his personal experiences during the Covid-19 pandemic
Dean David Gregory Interview
An interview with Dean of the Library David Gregory by Christian Wright discussing his professional and personal experiences during the Covid-19 pandemic
J. M. F. Wright and Newton's method of first and last ratios
We describe the approach taken by the nineteenth-century Cambridge textbook author J. M. F. Wright to a notoriously difficult part of Newton’s Principia: the method of first and last ratios. Wright suggested an algebraic point of view that, to his mind, would not only remove all prior confusion over the method, but would also serve as a new foundation for calculus as a whole. We examine the details of Wright’s approach, and discuss whether it was as successful as he claimed it to be
Geophis betaniensis Restrepo & Wright
3. Geophis betaniensis Restrepo & Wright Geophis betaniensis Restrepo & Wright 1987: 191. Holotype. Universidad del Valle (UVC) 7360, adult female, collected 18 February 1984 by J. H. Restrepo T. Typelocality. Eastern slope of the Cordillera Occidental, at Corregimiento de Betania (4 º 23 ’N, 76 º 21 ’W), 1680 m elevation, Municipio de Bolivar, Valle, Colombia. Distribution. Known only from the type locality in the Cordillera Occidental, Valle, Colombia. Species group. sieboldi (Lips & Savage 1994). Systematic references. Restrepo & Wright (1987), Lips & Savage (1994).Published as part of Wilson, Larry David & Townsend, Josiah H., 2007, A checklist and key to the snakes of the genus Geophis (Squamata: Colubridae: Dipsadinae), with commentary on distribution and conservation, pp. 1-31 in Zootaxa 1395 on page 5, DOI: 10.5281/zenodo.27368
FIGURE 7. Cranial diagram, 1 in Life history and larval chaetotaxy of Ahmetia achaja (Lepidoptera, Lycaenidae, Lycaeninae, Theclini, Cheritrina)
FIGURE 7. Cranial diagram, 1st instar A. achaja, frontal view. See text for explanation of labels.Published as part of Ballmer, Gregory R. & Wright, David M., 2008, Life history and larval chaetotaxy of Ahmetia achaja (Lepidoptera, Lycaenidae, Lycaeninae, Theclini, Cheritrina), pp. 47-59 in Zootaxa 1845 (1) on page 51, DOI: 10.11646/zootaxa.1845.1.3, http://zenodo.org/record/513471
FIGURE 11. 1 in Life history and larval chaetotaxy of Ahmetia achaja (Lepidoptera, Lycaenidae, Lycaeninae, Theclini, Cheritrina)
FIGURE 11. 1st instar A. achaja terminal segments (A7–10), dorsal view, cephalad at top. See text for explanation of labels.Published as part of Ballmer, Gregory R. & Wright, David M., 2008, Life history and larval chaetotaxy of Ahmetia achaja (Lepidoptera, Lycaenidae, Lycaeninae, Theclini, Cheritrina), pp. 47-59 in Zootaxa 1845 (1) on page 53, DOI: 10.11646/zootaxa.1845.1.3, http://zenodo.org/record/513471
Leveraging diversity in American academic medicine. The Harold Amos Medical Faculty Development Program
Peer reviewe
Landsat MSS classification of fire fuel types in Wood Buffalo National Park, northern Canada
J1: Global Ecology & Biogeography Letters; M3: Article; Milne, David Franklin, Steven E. Wilson, Bradley A. Ghitter, Geoff Heathcott, Mark McCaffrey, Thomas M. Ow, Charlotte F. Y.; Source Information: Mar1994, Vol. 4 Issue 2, p33; Subject Term: FOREST fires; Author-Supplied Keyword: Canada (Wood Buffalo National Park); Author-Supplied Keyword: Forest fire; Author-Supplied Keyword: Fuel type classification; Author-Supplied Keyword: Landsat data; Number of Pages: 0p; Document Type: Articl
Dynamics and folding of single two-stranded coiled-coil peptides studied by fluorescent energy transfer confocal microscopy
We report single-molecule measurements on the folding and unfolding conformational equilibrium distributions and dynamics of a disulfide crosslinked version of the two-stranded coiled coil from GCN4. The peptide has a fluorescent donor and acceptor at the N termini of its two chains and a Cys disulfide near its C terminus. Thus, folding brings the two N termini of the two chains close together, resulting in an enhancement of fluorescent resonant energy transfer. End-to-end distance distributions have thus been characterized under conditions where the peptide is nearly fully folded (0 M urea), unfolded (7.4 M urea), and in dynamic exchange between folded and unfolded states (3.0 M urea). The distributions have been compared for the peptide freely diffusing in solution and deposited onto aminopropyl silanized glass. As the urea concentration is increased, the mean end-to-end distance shifts to longer distances both in free solution and on the modified surface. The widths of these distributions indicate that the molecules are undergoing millisecond conformational fluctuations. Under all three conditions, these fluctuations gave nonexponential correlations on 1- to 100-ms time scale. A component of the correlation decay that was sensitive to the concentration of urea corresponded to that measured by bulk relaxation kinetics. Thetrajectories provided effective intramolecular diffusion coefficients as a function of the end-to-end distances for the folded and unfolded states. Single-molecule folding studies provide information concerning the distributions of conformational states in the folded, unfolded, and dynamically interconverting states.Author manuscript. Published in final edited form as: Proc Natl Acad Sci U S A. 2000 November 21; 97(24): 13021-13026.The final published version of this article is located at: http://www.pnas.org/cgi/reprint/97/24/13021NIH GM54616; to William F. DeGradoNIH GM12592; to Robin M. HochstrasserNIH GM48130; to William F. Degrado and Robin M. HochstrasserThis work was supported by GM54616 (to W.F.D.), GM12592 (to R.M.H.) and GM48130 (to W.F.D. and R.M.H.) with instrumentation developed under RR01348. D.S.T. was supported by National Institutes of Health Grant NRSA F32-GM18589.Also available in PubMed Central. PMCID:PMC2717
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