1,200 research outputs found
Development of CRISPRi based Transcriptional Gene Regulation Platform for Leuconostoc citreum
No full textDevelopment of CRISPR-dCas9 based Transcriptional Gene Regulation System for Lactic Acid Bacteria Leuconostoc citreum
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Immunomodulating activity of a polysaccharide isolated from mori cortex radicis
No full textThe immunomodulating activity of a polysaccharide isolated from Morus alba (PMA) root bark was examined in murine splenic lymphocytes. PMA enhanced proliferation of splenic lymphocytes in a synergistic manner in the presence of mitogens. However, PMA suppressed primary IgM antibody production from B cells, which was activated with lipopolysaccharide, a polyclonal activator, or immunized with a T-cell dependent antigen sheep red blood cells. Our observations showed that the immunomodulating activity of PMA increased lymphocyte proliferation and that PMA decreased antibody production from B cells, which was distinct from those of other plant-originated polysaccharides.open
Limb angular deformity correction using Dyna-ATC: surgical technique, calculation method, and clinical outcome
Get PDFPURPOSE: Dyna-ATC is a unilateral external fixator with angulator, lengthener, and translator, which allows for angular correction and compensation of the secondary displacement during angular correction. The purpose of this study is to introduce surgical technique and calculation methods and to evaluate the clinical outcome of angular deformity correction using Dyna-ATC.
MATERIALS AND METHODS: The amounts of secondary displacement were calculated with the distances between axis of correction of angulation, Center of Rotational Angulation, and osteotomy and the amount of angular deformity. The rate of angular correction was determined to distract the corticotomy at 1 mm/day. Clinical and radiographic evaluation was performed on 13 patients who underwent deformity correction using Dyna-ATC. There were 8 proximal tibia vara, 1 tibia valga, 2 varus and 4 valgus deformities on distal femur. One patient underwent pelvic support femoral reconstruction. Concomitant lengthening was combined in all femur cases. Mean age at surgery was 17.5 years (7 to 64).
RESULTS: All but one achieved bony healing and normal alignment with the index procedure. Mean mechanical axis deviation improved from 31.9 mm to 3.0 mm. The average amount of angular correction was 11.0° on tibiae and 10.0° on femora. The average length gain on femora was 6.4 cm, and the healing index averaged to 1.1 mo/cm. One patient underwent quadricepsplasty and one patient had three augmentation surgeries due to poor new bone formation.
CONCLUSION: We believe that Dyna-ATC is a useful alternative to bulky ring fixators for selective patients with angular deformity less than 30 degrees in the coronal plane around the knee joint.ope
sj-docx-1-msj-10.1177_13524585211060326 – Supplemental material for Brighter spotty lesions on spinal MRI help differentiate AQP4 antibody-positive NMOSD from MOGAD
No full textSupplemental material, sj-docx-1-msj-10.1177_13524585211060326 for Brighter spotty lesions on spinal MRI help differentiate AQP4 antibody-positive NMOSD from MOGAD by Jae-Won Hyun, Hye Lim Lee, Jaehong Park, Jiah Kim, Ju-Hong Min, Byoung Joon Kim, Seung Woo Kim, Ha Young Shin, So-Young Huh, Woojun Kim, Ji Won Seo, Ki Hoon Kim, Su-Hyun Kim and Ho Jin Kim in Multiple Sclerosis Journal</p
Side Impact Analysis of an Auto-body with 60TRIP Steel for Side Members
Get PDFBangkok, ThailandThis paper is concerned with the energy absorption efficiency of an auto-body side structure when it is fabricated with the conventional steel or the 60TRIP high strength steel. The energy absorption efficiency has been estimated with the dynamic crash analysis following the regulation of US-SINCAP. The analysis adopted the Johnson-Cook model for the dynamic material properties in order to achieve accurate crashworthiness assessment. The dynamic material properties were obtained from the dynamic material test with a tension split Hopkinson pressure bar test. The analysis result provided deformed shapes, amounts of penetration and accelerations at several important points during auto-body side crash. It is noted from the result that the use of the 60TRIP steel greatly improves the crashworthiness of the side members without sacrificing the weight and thus can be used for the light-weight design of an auto-body
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