1,627 research outputs found
Dr. Shanesha R.F. Brooks-Tatum, RWWL AUC, July 2011
No full textThis video is a conversation with Dr. Shanesha R.F. Brooks-Tatum. Dr. Brooks-Tatum talks about her book, "The Encyclopedia of Hip Hop Literature." Daniel Le, AUC Woodruff Library, is the interviewer
Letter: R.F. Pettigrew to H.L. Loucks, May 30, 1916
No full textR.F. Pettigrew articulates to H.L. Loucks his distaste for the book that Loucks recommended to him. Pettigrew also mentions that he would prefer to remain distanced from any conference with the author of the book. Pettigrew expresses great admiration and interest in Loucks' manuscript and desire to read it further
The evolution of fat grafting : from soft tissue augmentation to regenerative medicine
No full textThe Author traces the evolution of fat grafting over the years from the first publication in 1893, to the systematization of the technique thanks to the contribution of Sydney Coleman. In recent years studies on the nature of adipose tissue have shown that besides multiple resident cells, fat tissue contains stem cells (ADSCs) capable of differentiating in multiple lineages, such as bone, cartilage, muscle, nerve, etc. Thus, in addition to the traditional notion that fat is a high energy reservoir, it becomes apparent that fat is a repair organ providing the basis for soft tissue regeneration. Manipulation of ADSCs promises to affect different fields of medicine and provide the physician with a variety of regenerative medical therapies
Low-frequency model-order reduction of electromagnetic fields without matrix factorization
No full textElectrical Engineering, Mathematics and Computer Scienc
In memory of Paul Tessier, MD (1917-2008)
No full textThe Author traces the life and the surgical achievements of Paul Tessier, founder of craniofacial surgery
Old and new in fat grafting
No full textThe author traces the evolution of fat grafting over the years and shows the potential clinical applications in the different areas of the body
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women
No full textN-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of metabolism and food intake. We hypothesized that i) NAE plasma levels are associated with levels of total free fatty acids (FFAs) and their precursor fatty acid in fasting and non-fasting conditions and ii) moderate alcohol consumption alters non-fasting NAE levels. In a fasting and non-fasting study we sampled blood for measurements of specific NAEs and FFAs. In the fasting study blood was drawn after an overnight fast in 22 postmenopausal women. In the non-fasting study blood was sampled before and frequently after a standardized lunch with beer or alcohol-free beer in 19 premenopausal women. Fasting AEA levels correlated with total FFAs (r = 0.84; p <0.001) and arachidonic acid levels (r = 0.42; p <0.05). Similar results were observed for other NAEs with both total FFAs and their corresponding fatty acid precursors. In addition, AEA (r = 0.66; p <0.01) and OEA levels (r = 0.49;
Presentazione
No full textThe Author traces the evolution of Aesthetic Rhinoplasty in Italy from the first contribution published by G. Sanvenero Rosselli in 1931
Food-drug interactions in older people
No full textAs a general rule, the use of medication increases considerably with advancing years. In many cases, the elderly are using drugs for chronic and degenerative disease for longer periods of time. Polypharmacy, the combined use of several drugs, is generally regarded as a high risk, especially in a population that is already at risk because of various other factors. Not surprisingly, adverse drug reactions are a major problem in elderly persons and a common cause of admission to hospital. Compared to drug–drug interactions, the possible effects of food on drug actions or side-effects or, vice versa, the effects of drug use on (micro-)nutrient status are receiving far less attention. Drug-nutrient interactions can be bi-directional. The vast majority of the literature concentrates on the general mechanisms of food effects on drugs. By contrast, much less is known on the effects of drugs on micronutrient uptake, storage or elimination. Effects of medication on nutrient status are easily overlooked, as they generally develop slowly and may go together with other social, nutritional, clinical and other changes. It seems conceivable that drug-induced nutrient deficiencies are relatively more frequent in the elderly than in younger patients. This chapter discusses the most important examples and mechanisms of drug-nutrient interactions. Attention is also paid to general age-related changes in drug effects. In the elderly, dietary habits may change, food intake tends to decrease and requirements of macro- and micronutrients may be different. The use of medicinal preparations, including OTC products and food supplements is on average very high in the elderly population. The sparse systematic information that is available on drug-induced changes in nutrient status, for example B12 and D, is often limited to studies in younger people and comprise one drug at a time. It seems highly conceivable that drug-nutrient interactions are under-diagnosed in the elderly population and that there may be much more under the water line. This will be particularly true for specific groups such as frail elderly persons taking several drugs at a time, or persons having a low dietary intake. Health care professionals should be aware that an elderly person’s new symptoms can be attributable to an underlying drug–nutrient interaction
Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution
No full textNon-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit
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