176 research outputs found

    R.J.P. Williams

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    R.J.P. Williams FRS (1926-2015)

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    R.J.P. Williams FRS (1926-2015)

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    A Pauling biography

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    Sir-The review by R.J.P. Williams of Serafini's Pauling biography (Nature 342, 135; 1989) mostly displays William's musings as to what makes Pauling tick. While Williams is, of course, entitled to his opinions, our image of Linus Pauling is far more positive and we are especially incensed by the biographer's view of Paulings motivations, such as a need for tension and quarrels

    The mechanism of cytochrome oxidase and other reaction centres for electron/proton pumping

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    AbstractThe functional significance of the metal centres of cytochrome oxidase is deduced from the ways in which the centres are bound into its peptides. To this end use is made of structural knowledge of other metallo-proteins for dioxygen binding, haemocyanin and haemoglobin, and for electron transfer, cytochromes b and azurin. The order and manner in which the motions of helical sections of the oxidase are linked to proton pumping are suggested and a comparison is made with other proton pumps, for example that of ATP synthetases

    Iron in evolution

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    AbstractIron chemistry in the environment and in organisms is entwined. The iron surface minerals in solution for the first billion years of the planet were ferrous compounds. This ion became and has remained a major participant in organisms. The evolution of iron was due to its oxidation to insoluble ferric ions by oxygen released from organisms. The evolution of cellular iron chemistry then required uptake from this oxidised state. Use was expanded from the mainly electron transfer properties in the original reductive cell interior to employment in external oxidative chemistry. The environment/organisms evolution is that of one predictable chemical system
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