6,512 research outputs found
sj-docx-1-jop-10.1177_02698811221133469 – Supplemental material for The influence of stimulus onset asynchrony, task order, sex and hormonal contraception on prepulse inhibition and prepulse facilitation: Methodological considerations for drug and imaging research
No full textSupplemental material, sj-docx-1-jop-10.1177_02698811221133469 for The influence of stimulus onset asynchrony, task order, sex and hormonal contraception on prepulse inhibition and prepulse facilitation: Methodological considerations for drug and imaging research by Laura F Naysmith, Steven C R Williams and Veena Kumari in Journal of Psychopharmacology</p
sj-docx-2-jop-10.1177_02698811221133469 – Supplemental material for The influence of stimulus onset asynchrony, task order, sex and hormonal contraception on prepulse inhibition and prepulse facilitation: Methodological considerations for drug and imaging research
No full textSupplemental material, sj-docx-2-jop-10.1177_02698811221133469 for The influence of stimulus onset asynchrony, task order, sex and hormonal contraception on prepulse inhibition and prepulse facilitation: Methodological considerations for drug and imaging research by Laura F Naysmith, Steven C R Williams and Veena Kumari in Journal of Psychopharmacology</p
Mutant GABAA receptor g2-subunit in childhood absence epilepsy and febrile seizures
No full textCopyright © 2001 Nature Publishing GroupRobyn H. Wallace, Carla Marini, Steven Petrou, Louise A. Harkin, David N. Bowser, Rekha G. Pancha, David A. Williams, Grant R. Sutherland, John C. Mulley, Ingrid E. Scheffer & Samuel F. Berkovi
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
Full text linkBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Neurotransmitter receptor densities are associated with changes in regional Cerebral blood flow during clinical ongoing pain
No full textArterial spin labelling (ASL) plays an increasingly important role in neuroimaging pain research but does not provide molecular insights regarding how regional cerebral blood flow (rCBF) relates to underlying neurotransmission. Here, we integrate ASL with positron emission tomography (PET) and brain transcriptome data to investigate the molecular substrates of rCBF underlying clinically relevant pain states. Two data sets, representing acute and chronic ongoing pain respectively, were utilised to quantify changes in rCBF; one examining pre-surgical versus post-surgical pain, and the second comparing patients with painful hand Osteoarthritis to a group of matched controls. We implemented a whole-brain spatial correlation analysis to explore associations between change in rCBF (ΔCBF) and neurotransmitter receptor distributions derived from normative PET templates. Additionally, we utilised transcriptomic data from the Allen Brain Atlas to inform distributions of receptor expression. Both datasets presented significant correlations of ΔCBF with the μ-opioid and dopamine-D2 receptor expressions, which play fundamental roles in brain activity associated with pain experiences. ΔCBF also correlated with the gene expression distributions of several receptors involved in pain processing. Overall, this is the first study illustrating the molecular basis of ongoing pain ASL indices and emphasises the potential of rCBF as a biomarker in pain research
A versatile synthesis of linked cyclodextrins
No full textReactions of amino-substituted cyclodextrins with bis(3-nitrophenyl) oxalate, malonate, succinate and glutarate, and with diphenyl carbonate, afford a range of linked cyclodextrins. These include a- and ß-cyclodextrin dimers, joined by substitution at either C6 or C3, and asymmetric species with a ß-cyclodextrin bonded to an a-cyclodextrin and a C3-substituted cyclodextrin attached to a C6-substituted moiety.Easton, Christopher J ; Eyk, Steven J. van ; Lincoln, Stephen F ; May, Bruce L ; Papageorgiou, John ; Williams, Michael
Mathematics
No full text"Inservice education"--Final (unnumbered) p. of each document.; Includes bibliographical references.T. Teaching mathematics : elementary & middle grades / prepared by Steven P. Meiring (19 p.) -- K. Kindergarten mathematics / principal authors, James B. Wesson, Steven P. Meiring (18 p.) -- 1. First grade mathematics (18 p.) ; 2. Second grade mathematics (15 p.) ; 3. Third grade mathematics (18 p.) / principal author, C. Winston Smith, Jr. -- 4. Fourth grade mathematics (21 p.) ; 5. Fifth grade mathematics (19 p.) / principal author, James B. Wesson -- 6. Sixth grade mathematics (19 p.) ; 7. Seventh grade mathematics (23 p.) / principal author, William R. Speer -- 8. Eighth grade mathematics (19 p.) ; 8E. Eighth grade enrichment mathematics / principal author, James E. Schultz.A series of eleven monographs describing mathematics learning in the elementary and middle grades. These documents identify appropriate outcomes for each grade level and discuss teaching methods for helping students achieve those outcomes
FIGURES 19–21 in Isoperla riverae, a new stonefly species from the southeast Nearctic, with notes on sympatric species including the larval description of Isoperla lenati Szczytko & Kondratieff, 2015 (Plecoptera: Perlodidae)
No full textFIGURES 19–21. Isoperla riverae sp. n., adult male terminalia, (A) posteroventral lobe, (B) posterior lobe, (C) pair of small caudal lobes, (D) conical apical lobe, (E) paired hemispherical anterior lobes, Mayo River, Rockingham Co., North Carolina. 19. Lateral, 20. Dorsal, 21. Ventral.Published as part of Verdone, Chris J., Beaty, Steven R., Holland, Victor B. & Williams, Bronwyn W., 2023, Isoperla riverae, a new stonefly species from the southeast Nearctic, with notes on sympatric species including the larval description of Isoperla lenati Szczytko & Kondratieff, 2015 (Plecoptera: Perlodidae), pp. 437-470 in Zootaxa 5270 (3) on page 451, DOI: 10.11646/zootaxa.5270.3.3, http://zenodo.org/record/786014
FIGURES 1–4 in Isoperla riverae, a new stonefly species from the southeast Nearctic, with notes on sympatric species including the larval description of Isoperla lenati Szczytko & Kondratieff, 2015 (Plecoptera: Perlodidae)
No full textFIGURES 1–4. Isoperla lenati, larva, Flat Creek, Hoke Co., North Carolina. 1. Habitus, dorsal. 2. Head and pronotum, dorsal, (a) pale medial area anterior to median ocellus, (b) anterolateral pale spots, (c) mediolateral pale spots, (d) enclosed pale ocellar spot, (e) pale ocular areas. 3. Abdomen, dorsal. 4. Abdomen, ventral.Published as part of Verdone, Chris J., Beaty, Steven R., Holland, Victor B. & Williams, Bronwyn W., 2023, Isoperla riverae, a new stonefly species from the southeast Nearctic, with notes on sympatric species including the larval description of Isoperla lenati Szczytko & Kondratieff, 2015 (Plecoptera: Perlodidae), pp. 437-470 in Zootaxa 5270 (3) on page 441, DOI: 10.11646/zootaxa.5270.3.3, http://zenodo.org/record/786014
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