128 research outputs found
Using teaching case studies for management research
No full textTeaching case studies are widely deployed in business schools. They are
contextually rich in detail, and students learn by applying and adapting
theoretical concepts to specific business situations described in the case. This
article proposes a new way to use teaching case studies, as research materials
for academics. The article addresses three questions: (1) Can teaching cases be
used as an alternative to field research? (2) When can teaching case studies be
used as secondary data? and (3) How can teaching case studies be used as
secondary data? The article concludes that teaching case studies are an
unexploited and readily available source of research data, a source which should
be considered when going into the field and gathering primary data is not
possible
Modelling response to HIV therapy without a genotype: an argument for viral load monitoring in resource-limited settings
No full textIn the absence of widespread access to individualized laboratory monitoring, which forms an integral part of HIV patient management in resource-rich settings, the roll-out of highly active antiretroviral therapy (HAART) in resource-limited settings has adopted a public health approach based on standard HAART protocols and clinical/immunological definitions of therapy failure. The cost-effectiveness of HIV-1 viral load monitoring at the individual level in such settings has been debated, and questions remain over the long-term and population-level impact of managing HAART without it. Computational models that accurately predict virological response to HAART using baseline data including CD4 count, viral load and genotypic resistance profile, as developed by the Resistance Database Initiative, have significant potential as an aid to treatment selection and optimization. Recently developed models have shown good predictive performance without the need for genotypic data, with viral load emerging as by far the most important variable. This finding provides further, indirect support for the use of viral load monitoring for the long-term optimization of HAART in resource-limited setting
Balancing exploration and exploitation in transferring research into practice : a comparison of five knowledge translation entity archetypes
No full textBackground: Translating knowledge from research into clinical practice has emerged as a practice of increasing importance. This has led to the creation of new organizational entities designed to bridge knowledge between research and practice. Within the UK, the Collaborations for Leadership in Applied Health Research and Care (CLAHRC) have been introduced to ensure that emphasis is placed in ensuring research is more effectively translated and implemented in clinical practice. Knowledge translation (KT) can be accomplished in various ways and is affected by the structures, activities, and coordination practices of organizations. We draw on concepts in the innovation literature—namely exploration, exploitation, and ambidexterity—to examine these structures and activities as well as the ensuing tensions between research and implementation.
Methods: Using a qualitative research approach, the study was based on 106 semi-structured, in-depth interviews with the directors, theme leads and managers, key professionals involved in research and implementation in nine CLAHRCs. Data was also collected from intensive focus group workshops.
Results: In this article we develop five archetypes for organizing KT. The results show how the various CLAHRC entities work through partnerships to create explorative research and deliver exploitative implementation. The different archetypes highlight a range of structures that can achieve ambidextrous balance as they organize activity and coordinate practice on a continuum of exploration and exploitation.
Conclusion: This work suggests that KT entities aim to reach their goals through a balance between exploration and exploitation in the support of generating new research and ensuring knowledge implementation. We highlight different organizational archetypes that support various ways to maintain ambidexterity, where both exploration and exploitation are supported in an attempt to narrow the knowledge gaps. The KT entity archetypes offer insights on strategies in structuring collaboration to facilitate an effective balance of exploration and exploitation learning in the KT process
Signal Strength, Media Attention, and Resource Mobilization: Evidence from New Private Equity Firms
No full textThis is the author accepted manuscript. The final version is available from the Academy of Management via the DOI in this recordPast research has shown that new firms can facilitate resource mobilization by signaling their unobservable quality to prospective resource providers. However, we know less about situations in which firms convey multiple signals of different strengths—i.e., signals that are more or less correlated with unobservable firm quality. Building on a sociocognitive perspective, we propose that prospective resource providers respond differently to signals of different strengths and that the effectiveness of signals, especially weak signals, will be contingent on the media attention new firms receive. Empirically, we conduct a longitudinal analysis examining the ability of new private equity (PE) firms to raise a follow-on fund. Consistent with our theory, we find that unrealized performance, a relatively weak signal, positively influences fundraising. But we fail to find statistical evidence that its effect is weaker than that of realized performance, a relatively strong signal. Further, media attention strengthens the relationship between unrealized performance and fundraising, but media attention exerts less impact on the relationship between realized performance and fundraising. Taken together, our findings deepen our understanding of how new firms can mobilize resources with signals of different strengths and of how the media—as a key information intermediary—differently impacts their effectiveness.Richard M. Schulze Family Foundatio
Stedebouw en planologie - een onvoltooid project: Naar het communicatief handelen in de ruimtelijke planning en ontwerppraktijk
No full textArchitectur
Evidence for molecular distortion involving the carbonyl group in triplet states of carbonyl derivatives of naphthalene obtained from time resolved vibrational spectroscopic studies
No full textThe C=O stretching vibration appears in the infrared spectra of 2-naphthaldehyde (1), 2-acetonaphthone (2), 2-naphthoic acid (3), methyl 2-naphthoate (4) and 1,2-dihydro-3H-benz[e]inden-3-one (5) in the state T-1(pi pi*) between 1600 and 1700 cm(-1). There is a strong line in the Raman spectrum of 1-5 in the state S-0 arising from the C=O stretching mode, but such a line is lacking in their resonance Raman spectra when they are in the state T-1. This is attributed to a large amplitude out-of-plane twist of the C=O group in 1-4 and to a pyramidalization of the C atom in the C=O group of 5 in the equilibrium geometry of the state T-1.PT: J; CR: 1993, MOPAC 93 VERSION 6 1 ALBRECHT AC, 1961, J CHEM PHYS, V34, P1476 ARNOLD DR, 1968, ADV PHOTOCHEM, V6, P301 BEHRINGER J, 1972, INTRO THEORY RAMAN E, P1 BENSASSON RV, 1980, J CHEM SOC F1, V76, P1801 BEUKLER CA, 1970, SURVEY ORGANIC SYNTH, P807 CATALIOTTI R, 1984, J MOL SPECTROSC, V103, P56 CHAPMAN OL, 1967, REC CHEM PROGR, V28, P167 CHRISTENSEN SD, 1983, J RAMAN SPECTROSC, V14, P53 CI XP, 1989, CHEM PHYS LETT, V158, P263 DEVAQUET A, 1972, J AM CHEM SOC, V94, P5160 DIRAC PAM, 1927, P R SOC LOND A-CONTA, V114, P710 DOPP D, 1990, J PHOTOCH PHOTOBIO A, V53, P59 DOPP D, 1992, CHEM BER-RECL, V125, P983 DUBEN AJ, 1974, EXCITED STATES, V1, P295 FISHER MR, 1985, J CHEM PHYS, V82, P4721 FORMOSINHO SJ, 1991, ADV PHOTOCHEM, V16, P67 GEORGE MW, 1993, CHEM LETT, P873 GRABOWSKI ZR, 1979, J LUMIN, V18, P420 GRABOWSKI ZR, 1979, NOUV J CHIM, V3, P443 GUSTAFSON TL, 1983, J CHEM PHYS, V79, P1559 GUSTAFSON TL, 1984, J CHEM PHYS, V81, P3438 HAMAGUCHI H, 1984, CHEM PHYS LETT, V106, P153 HELLER HG, 1981, J CHEM SOC P2, P341 HOPKINS JB, 1986, CHEM PHYS LETT, V124, P79 HUPPERT D, 1981, J CHEM PHYS, V75, P5714 KARTHA VB, 1973, CAN J CHEM, V51, P1749 KAWASHIMA H, 1990, CHEM PHYS LETT, V165, P59 KEARNS DR, 1966, J AM CHEM SOC, V88, P5087 KITAMURA M, 1973, B CHEM SOC JPN, V46, P3056 KRAINOV EP, 1964, OPT SPECTROSC, V16, P415 KRAMERS HA, 1925, Z PHYS, V31, P681 LEDGER MB, 1972, J CHEM SOC F1, V539, P539 LIM EC, 1977, EXCITED STATES, V3, P305 LUI YH, 1974, J MOL SPECTROSC, V49, P214 MYERS AB, 1985, J CHEM PHYS, V83, P5000 NEVILLE AG, 1990, J AM CHEM SOC, V113, P1869 PAGE C, 1988, THESIS U SAARLAND SA PARKER CA, 1968, J CHEM SOC CHEM COMM, P749 PLANTENGA FL, 1984, J PHOTOCHEM, V24, P133 RAYNER DM, 1986, J PHYS CHEM-US, V90, P2882 RETTIG W, 1979, CHEM PHYS LETT, V62, P115 RETTIG W, 1982, J PHYS CHEM-US, V86, P1970 ROBINSON GW, 1958, CAN J CHEM, V36, P31 ROTKIEWICZ K, 1975, CHEM PHYS LETT, V34, P55 SALTIEL J, 1970, MOL PHOTOCHEM, V2, P331 SCHMID ED, 1977, SPECTRY, V6, P314 SHENG SJ, 1978, CHEM PHYS LETT, V57, P168 TAHARA T, 1987, J PHYS CHEM-US, V91, P5875 TAHARA T, 1988, CHEM PHYS LETT, V152, P135 TAHARA T, 1990, J PHYS CHEM-US, V94, P170 TAKEMURA T, 1982, CHEM PHYS LETT, V91, P390 TANG J, 1970, RAMAN SPECTROSCOPY, V2 VANEIJK AMJ, 1987, J AM CHEM SOC, V109, P6635 VANEIJK AMJ, 1988, J CHEM SOC FARAD T 2, V84, P1129 VANEIJK AMJ, 1990, J CHEM SOC FARADAY T, V86, P2083 VANZEYL PHM, 1984, CHEM PHYS LETT, V105, P127 VISSER RJ, 1980, J CHEM SOC FARAD T 2, V76, P453 VISSER RJ, 1983, J CHEM SOC FARAD T 2, V79, P347 VISSER RJ, 1985, CHEM PHYS LETT, V113, P330 WAGNER BD, 1994, J AM CHEM SOC, V116, P6433 WEISENBORN PCM, 1988, CHEM PHYS, V126, P425 WEISENBORN PCM, 1989, CHEM PHYS, V133, P437 YAMAUCHI S, 1988, J PHYS CHEM-US, V92, P2129 ZINK JI, 1991, ADV PHOTOCHEM, V16, P119; NR: 65; TC: 5; J9: CHEM PHYS; PG: 18; GA: RE469Source type: Electronic(1
Price or Privilege? Customer Perception on Loyalty Programs
No full textThe main purpose of the research is to understand how customers perceive loyalty programs. The author argues that types of loyalty programs could be classified into two: price based and privilege based. This research models that customer perceptions on loyalty programs, differ between these two types, and is contingent upon the relationship between customers and firm. Using settings of air-line domestic passengers and bank customers in Indonesia, the research provides evidence that price based rewards are perceived to provide higher utility perception in contractual relationships compared to non contractual relationships. However, this research failed to provide empirical support that privilege based rewards are perceived to provide higher utility perception in non contractual relation-ship compared to contractual relationship. Firms are therefore, encouraged to incorporate affective elements into their loyalty programs, on top of monetary elements, in order for the loyalty programs to be better perceived by their customers
More than a cognitive experience: unfamiliarity, invalidation, and emotion in organizational learning
No full textLiterature on organizational learning (OL) lacks an integrative framework that captures the emotions involved as OL proceeds. Drawing on personal construct theory, we suggest that organizations learn where their members reconstrue meaning around questions of strategic significance for the organization. In this 5-year study of an electronics company, we explore the way in which emotions change as members perceive progress or a lack of progress around strategic themes. Our framework also takes into account whether OL involves experiences that are familiar or unfamiliar and the implications for emotions. We detected similar patterns of emotion arising over time for three different themes in our data, thereby adding to OL perspectives that are predominantly cognitive in orientation
Comparative performances of HIV-1 RNA load assays at low viral load levels: results of an international collaboration
No full textLow-level viremia during antiretroviral therapy and its accurate measurement are increasingly relevant. Here, we present an international collaboration of 4,221 paired blood plasma viral load (pVL) results from four commercial assays, emphasizing the data with low pVL. The assays compared were the Abbott RealTime assay, the Roche Amplicor assay, and the Roche TaqMan version 1 and version 2 assays. The correlation between the assays was 0.90 to 0.97. However, at a low pVL, the correlation fell to 0.45 to 0.85. The observed interassay concordance was higher when detectability was defined as 200 copies/ml than when it was defined as 50 copies/ml. A pVL of similar to 100 to 125 copies/ml by the TaqMan version 1 and version 2 assays corresponded best to a 50-copies/ml threshold with the Amplicor assay. Correlation and concordance between the viral load assays were lower at a low pVL. Clear guidelines are needed on the clinical significance of low-level viremia
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