3,536 research outputs found
SUBTLEX-CY: A new word frequency database for Welsh
No full textWe present SUBTLEX-CY, a new word frequency database created from a 32-million-word corpus of Welsh television subtitles. An experiment comprising a lexical decision task examined SUBTLEX-CY frequency estimates against words with inconsistent frequencies in a much smaller Welsh corpus that is often used by researchers, the Cronfa Electroneg o’r Gymraeg (CEG), and three other Welsh word frequency databases. Words were selected that were classified as low frequency (LF) in SUBTLEX-CY and high frequency (HF) in CEG and compared with words that were classified as medium frequency (MF) in both SUBTLEX-CY and CEG. Reaction time analyses showed that HF words in CEG were responded to more slowly compared to MF words, suggesting that SUBTLEX-CY corpus provides a more reliable estimate of Welsh word frequencies. The new Welsh word frequency database that also includes part-of-speech, contextual diversity, and other lexical information is freely available for research purposes on the Open Science Framework repository at https://osf.io/9gkqm/
Voyage of the Northern Light : newspaper reports and articles.
No full textCover title.; For private circulation only.; Contains typescript copy of a letter from the author to the Daily telegraph.; Library's N copy is inscribed "To the Editor Bulletin, Joshua Slocum ... Strictly private". ANL; Electronic reproduction. Canberra, A.C.T. : National Library of Australia, 2009
Audiences' willingness to participate in Welsh-language media
No full textPhDContemporary media audiences expect to be able to interact with content, but in a minority language context, audience participation presents challenges related to audiences’ linguistic confidence. This thesis focuses on Wales, where media producers have suggested that audiences are often reluctant to interact with broadcast and online content in Welsh. To begin to understand this unwillingness, and how it might be overcome, the concept of willingness to participate (WTP) is coined as an extension of willingness to communicate (McCroskey & Baer 1985).
First, interviews with producers are analysed qualitatively to identify potential influences on audiences’ WTP. The analysis aims to assess the relative importance of various factors: audiences’ feelings of apprehension, self-perceived competence, language background and Welsh language ability, as well as the modality of participation (oral/written) and the level of demand placed on the audience.
Second, a questionnaire is designed and administered to 358 Welsh speakers, to examine audiences’ perceptions of different opportunities to participate in media content. A path model of WTP is proposed and tested using quantitative data from the survey. The results support the hypothesis that audiences’ apprehension and self-perceived competence predict WTP and that audience response varies according to the media context. While audiences’ Welsh language skills are important in explaining their WTP, other aspects of language background, such as Welsh language acquisition context, are found to be less important.
Third, the survey sample is grouped according to common patterns of WTP, to test whether the above effects are consistent across the population or whether different ‘types’ of audience exist. Using a combination of cluster analysis and thematic analysis of audience comments, four types of audience are proposed and described in detail. Finally, implications for sociolinguistic theory, language maintenance and media production practice are considered and recommendations made.Arts and Humanities Research Counci
Joshua Davis: Author of Spare Parts
No full textCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Flow cytometer optimisation and standardisation for the study of extracellular vesicles as translational biomarkers
No full textBackground: The term ‘extracellular vesicles’ (EVs) encompasses a range of vesicles. These include apoptotic vesicles (1000-300nm), microvesicles (30-1000nm), exosomes (~30-120nm) and retrovirus like vesicles (90-100nm). EVs have been linked to promising diagnostic, and therapeutic potentials. Their characterisation is poorly understood due to the lack of resolution and standardisation in detection equipment currently used.
Aims & Methods: In this thesis, I have developed methods for flow cytometer (FCM) resolution quantification, improvement, and standardisation. This involved building, testing and validating FCM optical models for EV analysis standardisation, and optimising FCM settings and protocols to increase resolution and decreasing variation in results. I then tested the benefits of these optimisations on EV analysis, which involved comparing optimised to non-optimised EV analysis protocols utilising clinical samples. Finally, EVs potential as translational biomarkers in non-alcoholic fatty liver disease (NAFLD) was investigated, employing the previously developed protocols in this thesis.
Results: FCM optimisations combined with a novel fluorescent assay resulted in a validated modelling technique, that allows diameter of EVs in plasma samples to be approximated using their scatter power, and separation of microvesicles, apoptotic vesicles, and residual platelets. Comparison of EV optimised to non-optimised protocols showed the FCM optimisation protocol to have increased EV absolute count reliability, and lower variation between results, when compared to a non-optimised FCM analysis protocol. Upon applying these methods to a biobank of clinical samples from individuals with NAFLD, novel insights were gained between the association of platelet-, endothelial-, and leukocyte-derived EVs in the progression of the disease. A clinically relevant finding being leukocyte EVs showing potential as a diagnostic marker of liver fibrosis severit
Evaluation of Welsh Women’s Aid
No full textCRG Research Ltd in partnership with Dr Amanda Robinson from Cardiff School of
Social Sciences, Cardiff University were commissioned by the Welsh Assembly
Government (WAG) to undertake the 'Evaluation of Welsh Women’s Aid' (WWA) to
“assess the effectiveness of the organisation in helping the Assembly Government to
achieve its domestic abuse strategy objectives.” (Research Specification p.1). The
report considers the efficiency and value for money provided by WWA and the
appropriateness of the organisation's structure, process, practices and objectives
Microvesicles as biomarkers in diabetes, obesity and non-alcoholic fatty liver disease: current knowledge and future directions
No full textNAFLD is the most common chronic liver disease, frequently associated with diabetes. Both of these insulin resistant states have increased cardiovascular risk factors associated, and a prevalent cause of mortality in these diseases. Microvesicles are heterogonously sized, phospholipid rich spheres released by cells upon activation and apoptosis. Evidence is continuing to accumulate of microvesicles being not only markers of disease severity but as also having a functional role in the pathophysiology of disease progression.<br/
Dataset for: Monolithically-integrated cytometer for measuring particle diameter in the extracellular vesicle size range using multi-angle scattering
No full textData associated with paper accepted by Royal Society of Chemistry Lab on a chip journal:
Butement, J., Holloway, P., Welsh, J. A., Holloway, J., Englyst, N., Horak, P., ... Wilkinson, J. S. (2020). Monolithically-integrated cytometer for measuring particle diameter in the extracellular vesicle size range using multi-angle scattering. Lab on a Chip. DOI: 10.1039/C9LC01182J </span
sj-docx-1-qjp-10.1177_17470218231190315 – Supplemental material for SUBTLEX-CY: A new word frequency database for Welsh
No full textSupplemental material, sj-docx-1-qjp-10.1177_17470218231190315 for SUBTLEX-CY: A new word frequency database for Welsh by Walter JB van Heuven, Joshua S Payne and Manon W Jones in Quarterly Journal of Experimental Psychology</p
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