134,138 research outputs found
Manufacturing Cells for Clinical Use
No full textCitation: Weiss, M. L., Rao, M. S., Deans, R., & Czermak, P. (2016). Manufacturing Cells for Clinical Use. Stem Cells International, 5. doi:10.1155/2016/1750697The growth in the number of registered clinical trials indicates that there is a need for cells for many types of cell therapy. Figure 1, which is reprinted from the excellent blog maintained by Alexi Bersenev, shows that the cell type used in most clinical trials worldwide is the mesenchymal stromal cell (MSC). The MSC type requires in vitro expansion to reach a clinical dose and thus there is a desire to optimize and standardize processes and procedures for MSC manufacture specifically for clinical use
Is the core mass-luminosity relation violated by the occurrence of the third dredge-up?
No full textThe core mass-luminosity (Mc-L) relation of thermally pulsing asymptotic giant branch (TP-AGB) stars is a key ingredient in synthetic calculations of their evolution. Recently, Herwig et al. (1998) have presented full calculations of TP-AGB models with strong dredge-up occurring already during early thermal pulses. The resulting luminosity evolution differs appreciably from the simple linear Mc-L relation. In this paper, we show that at least part of the luminosity evolution can be understood as being the result of two well-known effects: the gradual approach to the asymptotic behaviour that characterises the first thermal pulses, and the chemical composition changes of the envelope. Both effects are already implemented in the Mc-L relations used in synthetic models. Consequently, these models are able to reproduce the behaviour of full calculations. Whether additional effects, not yet taken into account, are present, can be decided only through additional calculations and data. We also comment on the validity of a linear Mc-L relation and its possible violation, as mentioned by Herwig et al
Michael Weiss interview
No full textAn interview with Michael Weiss, a Holocaust survivor, conducted by Dr. Sidney Bolkosky, Professor of History at the University of Michigan—Dearborn. Born in Kascony, Czechoslovakia, Mr. Weiss chronicles his experiences under the Czechoslovakians, Hungarians and Germans, both prior to and during the Second World War. Mr. Weiss and his family were shipped to the Hungarian ghetto of Beregszasz (Berehovo) in 1944. From Beregszasz, the family was deported to Auschwitz where his mother was gassed by the Germans. From Auschwitz, Weiss and his father were sent to Buchenwald and then on to Zeitz, located approximately fifteen miles south of Leipzig in Central Germany.An interview with Michael Weiss, a survivor of the Nazi holocaust of the Jews, by Sid Bolkosky.http://deepblue.lib.umich.edu/bitstream/2027.42/57191/3/Weiss950809-2.aiffhttp://deepblue.lib.umich.edu/bitstream/2027.42/57191/2/Weiss950809-1.aiffhttp://deepblue.lib.umich.edu/bitstream/2027.42/57191/1/Weiss.pd
Towards understanding the planetary nebula luminosity function
No full textWe report on a theoretical work in progress about the planetary nebula luminosity function. A new synthetic model is developed to follow the evolution of a planetary nebula and its central star, starting from the onset of AGB phase up to the white dwarf cooling sequence. Both H- and He-burning Post-AGB tracks are used. Basic properties of the circumstellar nebula are predicted, namely: the dynamics and chemical composition of the stellar ejecta, the photoionisation of H and He by the central star, the formation of a few relevant optical emission lines (e.g. Hβ;HeIIλ4686; [OIII]λ5007). As a first application, the planetary nebula luminosity function in the LMC is analysed adopting a population synthesis approach. It turns out that a reasonable reproduction of the observed bright end in the [OIII]λ5007 luminosity cannot be obtained assuming that all central stars are H-burners, but rather considering that the observed population of PNe is excited by a mixture of H- and He-burner central stars
Variations on a theme of Boole and Stein-Weiss
No full textWe give an alternative proof of a theorem of Stein and Weiss: The distribution function of the Hilbert transform of a characteristic function of a set E only depends on the Lebesgue measure |E| of such a set. We exploit a rational change of variable of the type used by George Boole in his paper "On the comparison of transcendents, with certain applications to the theory of definite integrals" together with the observation that if two functions have the same L^p norms in a range of exponents p_1<p<p_2 then their distribution functions coincide
A Generalised Sidelobe Canceller Employing Two-Dimensional Frequency Invariant Filters
No full textBased on the generalised sidelobe canceller (GSC), in this paper we propose a novel broadband adaptive beamformer, where the quiescent vector and blocking matrix are replaced by a series of two-dimensional frequency invariant filters (FIFs). A beam pointing towards the signal of interest takes the role of the quiescent vector, whereas the blocking matrix is formed by a number of beams covering the remaining space, with a zero response towards the signal of interest. As opposed to standard beamspace techniques, the FIFs are flexible in their number and are not required to posses a very low sidelobe level. Compared with a standard GSC, a faster convergence speed and lower computational complexity for the adaptive part can be achieved due to a shorter adaptive filter length
A Novel Method for Partially Adaptive Broadband Beamforming
No full textIn this paper, a novel subband-selective generalized sidelobe canceller (GSC) for partially adaptive broadband beamforming is proposed. The blocking matrix of the GSC is constructed such that its columns constitute a series of bandpass filters, which select signals with specific angles of arrival and frequencies. This results in bandlimited spectra of the blocking matrix outputs, which is further exploited by subband decomposition prior to running independent unconstrained adaptive filters in each non-redundant subband. We discuss the design of both the blocking matrix using a genetic algorithm for an efficient sum-of-power-of-two coefficient format and the filter bank for the subsequent subband decomposition. By these steps, the computational complexity of our subbad-selective GSC is greatly reduced compared to other adaptive GSC schemes, while performance is comparable or even enhanced due to subband decorrelation, as simulations indicate
Paraphrase de quatre pseaumes de David : en vers françois
No full textpar A. L. B. seigneur de Chanceaux sur Riolle ...In VersformBogensignaturen: A-B⁴ (B₄ weiss
A Fractionally Spaced DFE with Subband Decorrelation
No full textIn this paper we proposed a modification of the "classic" fractionally spaced decision feedback equaliser (FS-DFE) in order to increase the slow convergence rate of the oversampled feed-forward section for LMS type algorithms. This is performed by employing a subband structure for the latter part of the FS-DFE, which results in a decorrelation of the input. We motivate why an oversampled subband decomposition is beneficial and comment on the selection of the filter banks. As an additional benefit, computational savings arise if judicious implementation of the filter banks is combined with the internal decimation and expansion operations in the FS-DFE. Simulations for a sever multipath environment are presented
A Subband-Selective Broadband GSC with Cosine-Modulated Blocking Matrix
No full textIn this paper, a novel subband-selective generalized sidelobe canceller (GSC) for partially adaptive broadband beamforming is proposed. The columns of the blocking matrix are derived from a prototype vector by cosine-modulation, and the broadside constraint is incorporated by imposing zeros on the prototype vector appropriately. These columns constitute a series of bandpass filters, which select signals with specific angles of arrival and frequencies. This results in highpass-type bandlimited spectra of the blocking matrix outputs, which is further exploited by subbands decomposition and suitably discarding the low-pass subbands prior to running independent unconstrained adaptive filters in each non-redundant subband. By these steps, the computational complexity of a GSC implementation is greatly reduced compared to fully adaptive GSC schemes, while performance is comparable or even enhanced due to subband decorrelation in both spatial and temporal domains
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