3,710 research outputs found
Letter from Henry A. Webster to Thomas Lamb Eliot
No full texthttps://rdc.reed.edu/v1/resources/17e9abf7-b47a-4c5c-bf02-a16a1772f1c6/thumb/128.jp
Letter from Henry A. Webster to Thomas Lamb Eliot
No full texthttps://rdc.reed.edu/v1/resources/a000afa0-36bc-42a5-9da9-e33836bcd0ed/thumb/128.jp
Letter from Henry A. Webster to Thomas Lamb Eliot
No full texthttps://rdc.reed.edu/v1/resources/3c1591e4-77f6-472c-8e21-d2406fc17793/thumb/128.jp
Extensive genetic variation revealed within Biomphalaria pfeifferi from one river system in the Zimbabwean highveld
No full textHoffman J, Webster JP, Ndamba J, Woolhouse MEJ. Extensive genetic variation revealed within Biomphalaria pfeifferi from one river system in the Zimbabwean highveld. Annals of Tropical Medicine and Parasitology. 1998;92(6):693-698
Population genetics of the schistosome intermediate host Biomphalaria pfeifferi in the Zimbabwean highveld: implications for co-evolutionary theory
No full textWebster JP, Davis C, Hoffman J, Woolhouse MEJ. Population genetics of the schistosome intermediate host Biomphalaria pfeifferi in the Zimbabwean highveld: implications for co-evolutionary theory. Annals of Tropical Medicine and Parasitology. 2001;95(2):203-214
Development of novel multiplex microsatellite polymerase chain reactions to enable high-throughput population genetic studies of Schistosoma haematobium
No full textHuman urogenital schistosomiasis caused by Schistosoma haematobium is widely distributed across Africa and is increasingly targeted for control and regional elimination. The development of new high-throughput, cost-effective molecular tools and approaches are needed to monitor and evaluate the impact of control programs on the parasite populations. Microsatellite loci are genetic markers that can be used to investigate how parasite populations change over time and in relation to external influences such as control interventions.; Here, 18 existing S. haematobium microsatellite loci were optimised to enable simultaneous amplification across two novel multiplex microsatellite PCR's, each containing nine loci. Methods were developed for the cost effective and rapid processing and microsatellite analysis of S. haematobium larval stages stored on Whatman-FTA cards and proved robust on miracidia and cercariae collected from Zanzibar and Niger.; The development of these novel and robust multiplex microsatellite assays, in combination with an improved protocol to elute gDNA from Whatman-FTA fixed schistosome larval stages, enables the high-throughput population genetic analysis of S. haematobium. The molecular resources and protocols described here advance the way researchers can perform multi locus-based population genetic analyses of S. haematobium as part of the evaluation and monitoring of schistosomiasis control programmes
Draft toxicological profile for JP-5, JP-8, and jet A fuels
No full textA Toxicological Profile for JP-5 and JP-8 was released in 1998. This present edition supersedes any previously released draft or final profile.Chemical manager(s)/author(s): John Risher, Obaid Faroon, ATSDR, Division of Toxicology and Human Health Sciences, Atlanta, GA; Fernando Llados, Lisa Ingerman, Mario Citra, SRC, Inc., North Syracuse, NY
Host-parasite population genetics: a cross-sectional comparison of Bulinus globosus and Schistosoma haematobium
No full textDavies CM, Webster JP, Krüger O, Munatsi A, Ndamba J, Woolhouse MEJ. Host-parasite population genetics: a cross-sectional comparison of Bulinus globosus and Schistosoma haematobium. Parasitology. 1999;119:295-302
A voucher scheme for insectide treated nets in Ghana: development of a methodology for delivery systems evaluation
No full textThe key to effective scaling-up of coverage with insecticide treated nets is multiple effective
delivery systems that are complementary, each one adding incrementally to the overall
coverage. Generally, individual systems have been studied. A methodology is needed for
studying the effectiveness of individual delivery systems, mixes of delivery systems and their
relative contribution to coverage within a defined delivery system context. The insecticide
treated net voucher scheme in two regions of Ghana provided an opportunity to develop a
method of delivery systems evaluation.
The thesis consists of eight chapters. Chapter one is the introduction, and chapter two a\ud
review of the literature on the delivery of ITNs. Chapter three presents the study justification,
aim, objectives, conceptual framework, a description of the study setting and the methods
used in the study.
The thesis has four results chapters. In the first of these the quantitative coverage outcome
evaluation of the voucher scheme is presented. Delivery attribution is used to evaluate the
success of the voucher scheme. In the second results chapter, the intermediate processes in
the delivery system are defined and the effectiveness of each one is assessed overall and by
geographic area and socio-economic groups. In the third results chapter, qualitative methods
are used to interpret the quantitative findings and to describe and explain the impact of the
delivery systems context on the effectiveness of the intermediate processes of the voucher
scheme. In the fourth of the results chapters' recommendations on a methodology of
delivery system evaluation for ITNs and other public health interventions are made.
The final chapter is a discussion of the findings of the study in the two regions of Ghana and
their implications for the evaluation of delivery systems for ITNs and other public health
interventions particularly in relation to malaria control
Shock tube study of JP-10 ignition delay time
No full textJP-10 (exo-tetrahydrodicyclopentadiene, C10H16) ignition delay times were measured in a preheated shock tube. The vapor pressures of the JP-10 were measured directly by using a high-precision vacuum gauge, to remedy the difficulty in determining the gaseous concentrations of heavy hydrocarbon fuel arising from the adsorption on the wall in shock tube experiments. The whole variation of pressure and emission of the OH or CH radicals were observed in the ignition process by a pressure transducer and a photomultiplier with a monochromator. The emission of the OH or CH radicals was used to identify the time to ignition. Experiments were performed over the pressure range of 151-556 kPa, temperature range of 1000-2100 K, fuel concentrations of 0.1%-0.55% mole fraction, and stoichiometric ratios of 0.25, 0.5, 1.0 and 2.0. The experimental results show that for the lower and higher temperature ranges, there are different dependency relationships of the ignition time on the temperature and the concentrations of JP-10 and oxygen
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