1,722,045 research outputs found
Gregor WEBER & Martin ZIMMERMANN (Ed.), Propaganda - Selbstdarstellung - Repräsentation im römischen Kaiserreich des 1. Jhs. n. Chr.
No full textGregor WEBER & Martin ZIMMERMANN (Ed.), Propaganda - Selbstdarstellung - Repräsentation im römischen Kaiserreich des 1. Jhs. n. Chr.. In: L'antiquité classique, Tome 74, 2005. pp. 536-537
Gregor WEBER & Martin ZIMMERMANN (Ed.), Propaganda - Selbstdarstellung - Repräsentation im römischen Kaiserreich des 1. Jhs. n. Chr.
No full textGregor WEBER & Martin ZIMMERMANN (Ed.), Propaganda - Selbstdarstellung - Repräsentation im römischen Kaiserreich des 1. Jhs. n. Chr.. In: L'antiquité classique, Tome 74, 2005. pp. 536-537
The politics of global health governance: Whatever happened to "health for all by the year 2000"?
No full textAn evaluation of global health governance (GHG) may help advance conceptual as well as political debates on global governance. Thus the article analyzes and interprets shifts in GHG discourses against the backdrop of two phases of global governance, in broad-brush terms social democracy and neoliberalism. Insights are derived from a consideration of the competing political projects which underpin respective GHG conceptions, the actors which represent, defend, and advance them, and the structures which frame debates and policy initiatives. Within the context of the current global health crisis, exemplified clearly by the HIV/AIDS problem, it is argued that the main challenge for contemporary GHG is to re-establish within the policy environment the linkage between specific disease-oriented healthcare interventions and the underlying socio-economic context.<br/
Is intrathecal anti-CD20 an option to target compartmentalized CNS inflammation in progressive MS?
No full textnot availabl
Microglia-associated progression of multiple sclerosis: target identification and therapeutic engagement in human in vitro models
No full textAbstract Chronic progression of multiple sclerosis (MS) is likely to develop on the basis of a highly complex interaction of different mechanisms, which are probably already present at disease onset. While animal models have been instrumental in developing therapies for relapsing forms of MS, they have provided limited insight into the processes driving disease progression. To overcome these limitations, human in vitro models have emerged as powerful tools to dissect cellular mechanisms and identify novel therapeutic targets. Here, we highlight advances in modeling MS progression, using human induced pluripotent stem cell-derived systems, with a particular focus on microglia as key mediators of neuroinflammation and neurodegeneration. We critically discuss the strengths and limitations of current induced pluripotent stem cell-based microglia models, and their utility in target identification and therapeutic engagement. By emphasizing translational applications and methodological innovations, this Review provides a framework for leveraging human in vitro models to better understand and therapeutically modulate microglia-associated progression in MS
Global solidarity and responsibility Ethical requirements for green political theory in the age of 'globalization'
No full textAvailable from British Library Document Supply Centre-DSC:DXN051508 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
Following anti-CD20 treatment, compartment-specific repletion with immune-competent B cells depends on activation of reappearing B cells
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