258 research outputs found

    Deed of Trust, T. O. Conner, E. L. Ray, Guardian of Beach Heirs, June 17, 1904

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    This deed of trust, dated June 17, 1904, states that T. O. Conner is indebted to E. L. Ray and the Guardian of Benjamin and Bertha Beach for the sum of seventy-five dollars on his promissory note. The trust details the conditions of the loan, including the collateral and additional terms. A copy of the promissory note between Conner and Ray, dated June 17, 1904 is included with the deed of trust.https://scholarsjunction.msstate.edu/mss-webb-collection/2567/thumbnail.jp

    Human Intrinsic Factor Expression for Bioavailable Vitamin B12 Enrichment in Microalgae

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    Dietary supplements and functional foods are becoming increasingly popular complements to regular diets. A recurring ingredient is the essential cofactor vitamin B12 (B12). Microalgae are making their way into the dietary supplement and functional food market but do not produce B12, and their B12 content is very variable. In this study, the suitability of using the human B12-binding protein intrinsic factor (IF) to enrich bioavailable B12 using microalgae was tested. The IF protein was successfully expressed from the nuclear genome of the model microalga Chlamydomonas reinhardtii and the addition of an N-terminal ARS2 signal peptide resulted in efficient IF secretion to the medium. Co-abundance of B12 and the secreted IF suggests the algal produced IF protein is functional and B12-binding. Utilizing IF expression could be an efficient tool to generate B12-enriched microalgae in a controlled manner that is suitable for vegetarians and, potentially, more bioavailable for humans

    Promissory Note, T. O. Conner, J. M. Weatherly, and E. L. Ray to Merchants and Farmers Bank, April 8, 1926

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    In this promissory note to Merchants and Farmers Bank, dated April 8, 1926, T. O. Conner, J. M. Weatherly, and E. L. Ray promise to pay fifty-four dollars by December 1, 1926 at a ten percent interest rate.https://scholarsjunction.msstate.edu/mss-webb-collection/2552/thumbnail.jp

    The Colorado Trust’s Healthy Communities Initiative: Results and Lessons for Comprehensive Community Initiatives

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    · This article summarizes how 29 diverse communities throughout Colorado implemented the Colorado Healthy Communities Initiative (CHCI), which was conceived and funded by The Colorado Trust to engage community residents in the development of locally relevant strategies to improve community health. · In line with the World Health Organization’s Healthy Cities model, CHCI emphasized (a) inclusive, representative planning; (b) a broad definition of “health”; (c) consensus decision making; and (d) capacity building among local stakeholder groups. · Communities implemented an array of projects (on average, six per community) that extended well beyond traditional health promotion and disease prevention. The most common action projects focused on community problem solving, civic engagement, and youth development. Many of the grantees established projects or new institutions that had a long-term community impact. · Key success factors for CHCI included (a) a wellspecified planning model, (b) a planning process facilitated by expert consultants, (c) a unifying “healthy community” vision developed at the beginning of the process by diverse stakeholders, (d) a willingness by stakeholders to work collaboratively to define “key performance areas” and then to implement “action projects” to achieve them, and (e) an appropriate level of funding for implementation ($50,000 per site per year). · The outcomes and impacts of CHCI might have been improved by better anticipating the requirements for sustaining the energy and work initiated during the planning process. · At the end of the initiative, CHCI provided the funders with a broader, deeper understanding of the requirements, opportunities, and realities associated with promoting “community health.

    Check, E. L. Ray to E. L. Conner, September 17, 1925

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    This Kosciusko Bank check, dated September 17, 1925, is written to E. L. Coner for five dollars and forty cents by E. L. Ray, sheriff, for the Turnage Williams land sale case. A purple stamp in the upper right marks the check was paid on September 17, 1925.https://scholarsjunction.msstate.edu/mss-webb-collection/2548/thumbnail.jp

    A security perspective on code review: The case of Chromium

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    Modern Code Review (MCR) is an established software development process that aims to improve software quality. Although evidence showed that higher levels of review coverage relates to less post-release bugs, it remains unknown the effectiveness of MCR at specifically finding security issues. We present a work we conduct aiming to fill that gap by exploring the MCR process in the Chromium open source project. We manually analyzed large sets of registered (114 cases) and missed (71 cases) security issues by backtracking in the project’s issue, review, and code histories. This enabled us to qualify MCR in Chromium from the security perspective from several angles: Are security issues being discussed frequently? What categories of security issues are often missed or found? What characteristics of code reviews appear relevant to the discovery rate?Within the cases we analyzed, MCR in Chromium addresses security issues at a rate of 1% of reviewers’ comments. Chromium code reviews mostly tend to miss language-specific issues (e.g., C++ issues and buffer overflows) and domain-specific ones (e.g., such as Cross-Site Scripting); when code reviews address issues, mostly they address those that pertain to the latter type. Initial evidence points to reviews conducted by more than 2 reviewers being more successful at finding security issues.Acknowledgments: European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 642954Software Engineerin

    AAC Whitestar great northern dry bean

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    Balasubramanian, P., M端ndel, H.-H., Chatterton, S., Conner, R. L., and Hou, A. 2016. AAC Whitestar great northern dry bean. Can. J. Plant Sci. 96: xxx-xxx. AAC Whitestar is a high yielding great northern dry bean (Phaseolus vulgaris L.) cultivar with an upright, indeterminate bush (Type IIb) growth habit, large seed size and partial field resistance to white mould. AAC Whitestar was developed at the Agriculture and Agri-Food Canada (AAFC) Research and Development Centre, Lethbridge, AB. AAC Whitestar is suitable for irrigated wide row production in Alberta and Saskatchewan.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

    Court Fees Statement, M and F Bank, September 15, 1925

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    This bill lists fees charged in the Merchants and Farmers Bank verses M. T. Williams, et al case for court fees associated with the Circuit Court in Attala County, Mississippi on September 15, 1925. Fees include fees of Circuit Clerk, E. L. Conner, Sheriff, E. L. Ray, and printer, Wiley Sanders, respectively. The fees are marked paid in handwritten notes on the columns.https://scholarsjunction.msstate.edu/mss-webb-collection/2545/thumbnail.jp

    License to Practice as a Registered Pharmacist, Alata M. Burchfield, May 20, 1921

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    This license to practice as a registered pharmacist in the State of Mississippi, dated May 20, 1921, is awarded to Alta M. Burchfield of Kosciusko, Mississippi. The license is signed by the members of the State Board of Pharmacy and was recorded by E. L. Conner, the clerk. An illustration of the State of Mississippi shield is in the center of the license.https://scholarsjunction.msstate.edu/mss-webb-collection/2849/thumbnail.jp

    Development of new vaccines to combat aquaculture pathogens in South East Asian countries

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    Aquaculture is a rapidly growing sector, with large economic value and potential. However, aquaculture is severely hampered by disease outbreaks, which cause large losses in production. Antibiotics are often used in South East Asian countries to control disease outbreaks, due to their low cost and ease of use, nevertheless they are ineffective against viral infections and give rise to antibiotic resistant strains. This research sought to develop more convenient and low-cost alternatives, using bacteria and microalgae to express proteins and double stranded RNA (dsRNA) which could then be administered orally. Soluble and insoluble expression of Glyceraldehyde-3phosphate dehydrogenase (GapA) from Streptococcus agalactiae, a bacterial pathogen which causes high mortality in fish, was achieved in Escherichia coli in shake flask and fed-batch fermentation. Purified soluble and insoluble protein were administered orally to red hybrid tilapia fish and challenged with S. agalactiae resulting in a 51.1% and 75.6% survival respectively, compared to 13.3% in the control group. GapA was expressed in the chloroplast of the microalgae Chlamydomonas reinhardtii and later optimised with yields of up to 18 mg/L being achieved. Freeze dried transgenic C. reinhardtii showed that protein could be detected up to 54 days when stored at room temperature, showing large potential for microalgae for the production and oral application of vaccines. In addition, two dsRNA expressing C. reinhardtii strains were generated targeting key viral genes of the white spot syndrome virus, which causes large losses in shrimp aquaculture. Part of the VP9, thought to be involved in viral replication, and ORF366, part of the nucleocapsid, genes were expressed in the chloroplast as dsRNA reaching yields of 3.86±1.07 µg/L (VP9) and 11.63±5.84 µg/L (ORF366). However, challenge trial data appeared to show no real benefit to survival rates to shrimp over the control (dsRFP expressing) strain. Finally, an alternative strategy to help identify biomarkers for disease resistance was also developed using an antibody generated to target Alpha2-macroglobulin (A2M) in Brown-marbled grouper. Blood serum samples from fish more resistant to infections of Vibrio parahaemolyticus showed higher levels of A2M, indicating A2M as a potential disease resistance biomarker
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