38,982 research outputs found

    F. A. L. Watts

    No full text
    "[Sgt. name obscured, rewritten by quiltmaker]F.A.L. Watts 23/21 Bn Darwin A. River. 1942-43."[Sergeant name obscured, rewritten by quiltmaker]F.A.L. Watts 23/21 Battalion, Darwin, Adelaide River. 1942-43

    Cowboy Narrative - Neal S. Watts

    No full text
    A transcript of a Cowboy Narrative, or Rangelore, interview conducted by Sheldon Gauthier for the Works Progress Administration\u27s Federal Writers\u27 Project in the 1930s with former cowboy Neal S. Watts. Watts was born in 1859 on his father\u27s farm in Shelby County, Texas and moved to present-day Mansfield, Texas in 1868. In his interview, he describes the abundance of wild game and farming methods in Shelby County. He later began working as a cowhand for L. H. Stevens in Tarrant County, and describes roping cattle, applying a salve to injured cattle, roundups, stampedes, rustlers, and the roles of each cowhand on a trail drive. The interview also describes in detail the growth of Mansfield and the building of the Texas-Pacific Railroad to Fort Worth.https://mavmatrix.uta.edu/specialcollections_workprojectsadministration/1087/thumbnail.jp

    Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing

    No full text
    We report that combining a DNA analog (2?F-ANA) with rigid RNA analogs [2?F-RNA and/or locked nucleic acid (LNA)] in siRNA duplexes can produce gene silencing agents with enhanced potency. The favored conformations of these two analogs are different, and combining them in a 1–1 pattern led to reduced affinity, whereas alternating short continuous regions of individual modifications increased affinity relative to an RNA:RNA duplex. Thus, the binding affinity at key regions of the siRNA duplex could be tuned by changing the pattern of incorporation of DNA-like and RNA-like nucleotides. These heavily or fully modified duplexes are active against a range of mRNA targets. Effective patterns of modification were chosen based on screens using two sequences targeting firefly luciferase. We then applied the most effective duplex designs to the knockdown of the eIF4E binding proteins 4E-BP1 and 4E-BP2. We identified modified duplexes with potency comparable to native siRNA. Modified duplexes showed dramatically enhanced stability to serum nucleases, and were characterized by circular dichroism and thermal denaturation studies. Chemical modification significantly reduced the immunostimulatory properties of these siRNAs in human peripheral blood mononuclear cells. <br/

    Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)

    No full text
    In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola

    Crocodile

    No full text
    A crocodile, approximately 20 feet, caught at Adelaide River near Humpty Doo. L-R: Herb Widdup; Clarrie Agars; Jim Watts; F. I. H. Finniss; Jack Kepert; Jack Blakeley; Don Watts; Bill Murray. Similar photo to PH0352/0199.Unknown.Date:193

    The Doppler Spectra of Medium Grazing Angle Sea Clutter; Part 1: Characterisation

    No full text
    This paper is concerned with the characterisation of Doppler spectra from high range resolution X-band radar sea clutter observed from an airborne platform over the range of grazing angles, 15° to 45°. It is observed that when looking up or down wind there is a strong correlation between mean Doppler shift and local spectrum intensity. When combined with random fluctuations of spectrum width, these characteristics give the spectra a temporal and spatial variability. This behaviour has previously been observed in low grazing angle data and these results confirm the wider applicability of the models developed using that data. The modelling method is also extended here to capture the bimodal behaviour observed with high intensity returns from breaking waves looking up or down-wind

    Author Correction: Impact of ezetimibe on plasma lipoprotein(a) concentrations as monotherapy or in combination with statins: a systematic review and meta-analysis of randomized controlled trials (Scientific Reports, (2018), 8, 1, (17887), 10.1038/s41598-018-36204-7)

    No full text
    The original version of this Article contained a typographical error in the spelling of the author Cesare Sirtori, which was incorrectly given as Cesare Sirotri. Additionally, the original version of this Article omitted an affiliation for Amirhossein Sahebkar. The correct affiliations for Amirhossein Sahebkar are listed below: Halal Research Center of IRI, FDA, Tehran, Iran. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. This has now been corrected in the HTML and PDF versions of this Article

    Sous-facteurs de L(F∞) d'indice 4cos2π/n,n≥3

    No full text
    Let Q be a factor of type II1, λ a number in the Jones discrete series {4cosπ/m:m≥3}, and {ei} the Jones projections associated with λ. Denote by A2n and A1n the finite-dimensional von Neumann algebras generated, respectively, by {1,e2,⋯,en} and {1,e1,⋯,en}, with the corresponding traces. The author shows that, for n sufficiently large, the index of the inclusion An=(Q⊗A2n)∗A2nA1n⊂(Q⊗A2n+1)∗A2n+1A1n+1=An+1 is equal to λ (here ∗ denotes the reduced, amalgamated free product of the algebras in question). Using the random matrix model of Voiculescu, he proves that if Q is the von Neumann algebra L(F∞) of the free group with infinitely many generators, then An is isomorphic to L(F∞). The two facts together imply the existence, for any λ in the Jones discrete series, of an irreducible subfactor of L(F∞) of index λ. This constitutes the first example of a nonhyperfinite, non-Γ II1 factor such that its Jones invariant is fully computable (the existence of nonirreducible subfactors of L(F∞) for any index ≥4 is a simple consequence of known results)

    Transantarctic Mountains Uplift revisited with Gravity data and Flexural modelling

    No full text
    The Transantarctic Mountains (TAM) are often regarded as the uplifted flank of the West Antarctic Rift System (WARS). The TAM are, however, higher, longer and wider compared to other rift flanks. Unravelling the processes responsible for these unique characteristics, requires an improved knowledge of the deeper crustal architecture and uplift mechanisms of the TAM. Limited wide-angle and passive seismic data have provided important insights into the boundary between East and West Antarctica, but TAM uplift mechanisms have remained both controversial and poorly constrained. We present new models for the crustal structure and uplift mechanisms over the Victoria Land part of the TAM, based on a new compilation of gravity data, including data from the adjacent Ross Sea Rift (RSR) and Wilkes Subglacial Basin (WSB). To reduce inherent ambiguities associated with gravity modelling, we also incorporated independent wide-angle and passive seismic constraints onshore, and existing seismic reflection interpretations within the RSR. Our preferred model indicates that the crust under the TAM is 40±2 km thick, while the crust under the WSB is 33±3 km thick. A ca 5-7 km-thick root is imaged under the TAM. We propose that the root may be inherited from Ross-age orogenic events that thickened the crust. The high apparent density of the root implies a reduced buoyancy, such as inferred over several old mountain belts, including the Urals, the Caledonides of eastern Greenland, and older Proterozoic orogens. Additional thickening of the dense root may reflect later underplating processes, either linked to Jurassic magmatism, or alternatively to Cretaceous-Cenozoic rifting. Our flexural models demonstrate, however, that root preservation and magmatic underplating alone cannot explain all the TAM elevation. We show that 2/3 of the elevation arise from the combined effect of mechanical unloading along the TAM rift flank, erosion, and thermal uplift due to warmer upper mantle underlying the WARS. Preliminary 3D flexural modelling suggest that although these mechanisms may broadly explain the TAM, significant differences in rift structure, inheritance, mantle flow and erosion histories need to be taken into account to explain the observed segmentation of the range

    Peering Beneath the Transantarctic Mountains Rift Flank with New Gravity Data

    No full text
    The West Antarctic Rift System (WARS) is one of the largest and most poorly understood continental rift systems. It is flanked by the Transantarctic Mountains (TAM), which extend for over 3,000 km from the Ross Sea Rift (RSR) to the Weddell Sea. Compared to other rift flanks the range is significantly higher, longer and wider. Unravelling the tectonic, climate and ice sheet processes, which may be responsible for these unique characteristics, requires an improved knowledge of its deeper crustal architecture and uplift mechanisms. Limited wide-angle and passive seismic data have provided some insight into the boundary between East and West Antarctica, but uplift mechanisms for the TAM remain controversial. TAM uplift has been linked to Cretaceous distributed extension in the WARS, Cenozoic flexure along its flank, and erosional denudation related to glacial incision at the margin of the East Antarctic Ice Sheet, or pre-glacial fluvial incision. The most recent hypothesis is that the TAM form the edge of an elevated plateau, which collapsed in response to distributed Cretaceous extension in the WARS. Here we present new models for the crustal structure and uplift mechanisms for the TAM, based on a compilation of aerogravity and land gravity data over the Prince Albert Block (PAB) and marine gravity in the RSR. We incorporated independent wide-angle and passive seismic constraints onshore and existing seismic reflection interpretations across the Victoria Land Basin within the RSR. Our preferred model indicates that the crust beneath the PAB is 40±2 km thick. A 5 Km-thick root is imaged, in good agreement with previous interpretations further south over the TAM. We propose that a significant component of the root (ca. 3 km) is due to magmatic underplating. Flexural models show that magmatic underplating could drive up to 1/3 of TAM uplift. The remainder is modelled as a function of mechanical unloading, erosion, and thermal buoyancy
    corecore