54,044 research outputs found
Watson, F N, QX20874
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/424346Surname: WATSON. Given Name(s) or Initials: F N. Military Service Number or Last Known Location: QX20874. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 27515.252209
Item: [2016.0049.56607] "Watson, F N, QX20874
An experimental study on trailing edge crack detection for wind turbine blade using airfoil aerodynamic noise
No full textRecent decades have witnessed more and more wind turbines (WTs) being installed onshore and offshore. Health condition monitoring for WTs structures and components is increasingly becoming a compelling concern for stable power output and operational safety of a wind farm [1]. Blade damages seem to occur with a higher probability ahead of other components (e.g., gearbox and generator) damages [2]. After reviewing traditional damage detection approaches and their limitations [3], in this research a new non-contactable approach to detecting trailing edge (TE) damages is proposed based on airfoil aerodynamic noise measurements using a microphone array. In the experiment, four changeable TE parts with rectangular cracks (damaged width W of 0.2mm, 0.5mm, 1.0mm and 2.0mm) for a NACA0018 airfoil (chord C=200mm, span L=400mm) are designed and an example with W=0.2mm is shown in Fig.(a). The TEs with cracks have the same solid thickness as the baseline one (h_solid=0.76mm, standard NACA0018 airfoil TE thickness with chord of 200mm) but different dimensions of total TE thickness (h=W+h_solid). A phased microphone array with 64 microphones is used for acoustic measurement then beamforming is applied to extract TE noise and source power integration is performed within a 200×200mm2 region centred at TE midpoint [4][5]. Fig.(b) shows sound pressure levels (SPLs) L_p at the integrated region of four damaged cases as well as baseline with the frequency resolution of 10Hz under the freestream velocity U of 35m/s and geometrical angle of attack (AoA) alpha of 0º. The cases with smaller cracks show less remarkable tonal peaks compared with the one of W=2.0mm (~4dB); when the crack size is smaller the spectral peak broadens. These peaks or humps are attributed to the periodic vortex shedding from blunt TEs. Fig.(c) shows the SPL differences Delta L_p between the damaged cases and baseline; frequency is normalized as TE-thickness-based Strouhal number St. Local maxima of Lp are present at approximately St = 0.1 [6]. In the experiment, it is difficult to extract the spectral peaks or humps if the effective AoA (alpha*) [6] is more than 2.40º because the boundary layer on suction side becomes thicker and the asymmetry of boundary layers prevents coherent and periodic vortex shedding [7]. In Fig.(d), the discrete points are the St at peak L_p (St_peak) versus the ratio of TE thickness and averaged displacement thickness of pressure and suction sides (overline delta *) extracted from available cases (U=15m/s, 20m/s, 25m/s, 30m/s and 35m/s); the grey and blue curves are obtained from models reported in [6] with solid angle (Psi) of 20º and 23.76º (baseline solid angle), respectively. The points of St_peak versus thickness ratio show a good agreement with the prediction model [6]. This means that particularly for smaller cracks at the first stage of damaged process, the effect of solid angle can be neglected and considered as a minor and adjunctive factor. The TE thickness retrieved through the application of the model can be used as a prediction of the damage level. Additional data obtained from experiments with turbulent inflow will be presented to assess if the approach proposed is still feasible in more realistic turbulent inflow conditions. Keywords: wind turbine blade; trailing edge crack; damage detection; aerodynamic noise. Images: Link: https://s3-eu-west-1.amazonaws.com/static.vcongress.de/cms/forwind/paper/417dd783-7a7c-424d-a4d3- 55ce31fa41e1.png Description: (a) An example of NACA0018 airfoil with a TE crack of 0.2mm. (b) SPLs with resolution of 10Hz (U=35m/s and alpha=0º). (c) Corresponding SPL differences compared with baseline case normalized as peak St. (d) Relations of peak St and thickness ratio: discrete points are the experimental date; grey and black curves are prediction models Brooks et al. proposed with solid angle of 20º and 23.76º. References: [1] Tautz-Weinert, J. and Watson, S.J., 2016. Using SCADA data for wind turbine condition monitoring–a review. IET Renewable Power Generation, 11(4), pp.382-394. [2] Yang, W., Peng, Z., Wei, K. and Tian, W., 2016. Structural health monitoring of composite wind turbine blades: challenges, issues and potential solutions. IET Renewable Power Generation, 11(4), pp.411-416. [3] Du, Y., Zhou, S., Jing, X., Peng, Y., Wu, H. and Kwok, N., 2020. Damage detection techniques for wind turbine blades: A review. Mechanical Systems and Signal Processing, 141, p.106445. [4] Merino-Martínez, R., Carpio, A.R., Pereira, L.T.L., van Herk, S., Avallone, F., Ragni, D. and Kotsonis, M., 2020. Aeroacoustic design and characterization of the 3D-printed, open-jet, anechoic wind tunnel of Delft University of Technology. Applied Acoustics, 170, p.107504. [5] Carpio, A.R., Avallone, F., Ragni, D., Snellen, M. and van der Zwaag, S., 2020. Quantitative criteria to design optimal permeable trailing edges for noise abatement. Journal of Sound and Vibration, 485, p.115596. [6] Brooks, T.F., Pope, D.S. and Marcolini, M.A., 1989. Airfoil self-noise and prediction. [7] Moreau, D.J. and Doolan, C.J., 2016. Tonal noise production from a wall-mounted finite airfoil. Journal of Sound and Vibration, 363, pp.199-224
Getting Started as a Medical Teacher in Times of Change
No full textMedical school teaching is a skill that is very often learned on the job. The faculty comprised of researchers and clinicians are expert in many biomedical disciplines, but familiarity with learning theories and pedagogy are usually not included in their knowledge and skill sets. The pressure to see patients and acquire extramural funding leaves little time for faculty to learn how to teach. When coupled with the natural attrition of senior faculty it is necessary to start junior faculty on the correct path to being effective medical educators who are capable of lecturing and facilitating. Institutions cannot afford to have medical educators learn through trial and error. The standards set by the Liaison Committee on Medical Education (LCME) are also creating an urgency to produce competent teachers as quickly as possible. Novice teachers need to be able to use these standards to align their teaching with goals, objectives and the appropriate pedagogy. This article is designed to be a self-directed guide describing some essentials that a newly hired faculty member can quickly use to get started. An institutional faculty development program can then serve to build upon and enrich the experience for the new faculty member.This is the authors' accepted manuscript of the article. The final publication is available at Springer via http://dx.doi.org/doi:10.1007/s40670-014-0098-y.Peer reviewe
Paleanotus chrysos Watson, 2015, n. sp.
No full text<i>Paleanotus chrysos</i> n. sp. <p>(Figs 1 I; 8A −L; 9)</p> <p> <b>Type material.</b> Holotype: NTM W.23203, Western Pacific Ocean, QLD, GBR, North Direction Island, 14º44.62’S, 145º30.72’E, CReefs, LI-08-019, coll. C. Glasby, Apr 2008, (23E, L: 2.5 mm, W: 0.45 mm). Paratypes: NTM W.25641, same locality as holotype, (6, including female with large eggs, 22 E, L: 2.5mm, W: 0.6 mm).</p> <p> <b>Other material examined.</b> NTM W.23688, Yonge Reef, 14º34.40’S, 145º37.11’E, CReefs, LI-10-116, Sep 2010, (3: 1, 21E, L: 1.2 mm, W: 0.6 mm); NTM W.23673, Waining Reef, 14º 27.84S, 145º 19.19E, CReefs, LI-09- 0 23, coral rubble, 2 m, coll. C. Watson, Feb 2009, (3E); NTM W.23669, Lizard Island, Coconut Beach, 14º40.88’S, 145º28.35’E, CReefs, LI-09-002, 2 m, coll. C. Watson, Feb 2009, (1, 19E, L: 1.2 mm, W: 0.6 mm); NTM W.23604, Mermaid Beach, 14º38.75’S, 145º27.21’E, CReefs, LI-08-006, fine green algae on sand, 12 m, Apr 2008, (1, 21 E); NTM W.25640, North Point, 14º38.73’S, 145º27.2’E, CReefs, LI-08-020, rubble, 2 m, coll. C. Watson & N. Bruce, Apr 2008, (1, 19E, L: 1.5 mm, W: 0.55 mm); MV F.214507, North east of Townsville, muddy sand, 26 m, (1NE); MV F.214506, Britomart Reef, 18º17’S, 146º38’E, algae & sponges, 3 m, Nov. 1982, (1, 22E, L: 2.3 mm, W: 0.7 mm); MV F 214509, same locality, encrusting algae, Nov 1982, (4, NE); MV F.125877, same locality, reef front, encrusted dead coral with fine red algae, Nov 1982, (1NE); NTM W.23190, Heron Island, CReefs, HI-09-046, Sykes Reef, rubble, 10 m, Nov 2009, (1, 17NE); NTM W.23656, CReefs, HI-10-009, Sykes Reef, rubble, 14 m, coll. M. Blazewicz-Paszokowycz, Nov 2010, (2: 1, 22NE, L: 2.2 mm, W: 0.55 mm; 1, 24E, L: 2.0 mm, W: 0.75 mm); NTM W.23658, North East Lamont Reef, 23º35.20’S, 152º3.73’E, CReefs, HI-10-013, 21 m, coll. M. Capa, Nov 2010, (1, 22E, L: 2 mm, W: 0.65 mm); SMNH 97309, Western Pacific, France, New Caledonia, Loyalty Islands, Lifou, 17 m, (1, 20E, L: 2 mm, W: 0.65 mm).</p> <p> <i>Paleanotus chrysos</i> species complex</p> <p>NTM W.13169, Philippines, Luzon, Cape Bolinao, coral rubble, red algae & sponge, 12 m, coll. B. Russell, Oct 1995, (1NE, W: 0.9 mm).</p> <p> <b>Description.</b> (based on holotype and other material where noted). Very small, elongate body with distinctive paleal notochaetae coloured deep yellow to bright gold. Paleae in neat, slightly ‘prickly’, raised fans over dorsum ie. not completely flattened as in other <i>Paleanotus</i> species. Neuropodia extend a little beyond notopodia.</p> <p>Prostomium with 2 pairs large, dark maroon eyes often merged; median antenna slender, subulate; large, glandular nuchal fold covers posterior prostomium. Segment 2 (chaetigerous segment 1) with 2–4 slender, pointed paleae with 3 ribs (Fig. 8 A, B).</p> <p>Notochaetae of mid-body notopodium composed of 2 slender, pointed laterals with 4–5 ribs; subunit 1 paleae usually absent, sometimes 1–2 small spines present (Fig. 8 C). Main paleae number 6–8 with 13–15 (16) ribs. Paleae with rounded to slight sloping brow, robust margin serration; broad, curved apices. At moderate magnification superior surface of main paleae appears smooth; at high magnification ribs appear thickened, especially basally, with about 4–6 b.l. ribs. Slender dorsal cirri about 2/3 length of main paleae fan (Figs 1 I; 8K; 9). Median paleae number 3; distinctive narrow shape with sloping brow. Lizard Island material median paleae slender with distinct ‘upswept’, broad apices, 8–11 (12) ribs (Fig. 8 E, D). Heron Island, New Caledonian median paleae broader with 9–12 ribs (Fig. 8 K, L). Median paleae appear smooth; under high magnification 5 b.l. ribs visible, especially basally.</p> <p>Neurochaetal types of mid-body neuropodium composed of 2 superior, very slender falcigers; about 4 midsuperior falcigers; 6–8 mid-group falcigers. Latter three groups with pronounced basal serrations. Inferior group of shorter falcigers with slender blades, number 4–6. Total number about 20 (Fig. 8 F–J). Ventral cirri short, subulate.</p> <p> <b>Remarks.</b> <i>Paleanotus chrysos</i> n. sp. has the smallest maximum body segment number and length compared to all other species described in this paper; e.g., mature GBR specimen 24E, length 2.6 mm, width 0.75 mm; the New Caledonian specimen, 20E and length 3.7 mm. <i>Paleanotus chrysos</i> n. sp. is coloured deep yellow in northern GBR specimens, deep mustard yellow to gold in reefs off Townsville, and bright brassy gold in material from Heron Island, southern GBR: a depth of notochaetal pigmentation not seen in any of the other small <i>Paleanotus</i> species.</p> <p> <i>Paleanotus chrysos</i> n. sp. is further differientated by possession of pointed lateral paleae with small number of ribs and short spine/s and the absence of sub-unit 1 paleae. The median paleae shape is unique and horizontal striae are observed more widely separated in the basal quarter of paleae becoming finer distally (Fig. 8 E). Neurochaetal types are similar to those of other species but possess a greater degree of basal serration, particularly of the midgroup falcigers (Fig. 8 G–I). An ovigerous female paratype specimen (starting to disintegrate), has large eggs present from chaetiger 6, measuring 200–250 µm in diameter (Fig. 9).</p> <p> Body size and chaetal morphology of individuals from northern and southern GBR specimens, reefs off Townsville and New Caledonia overall agrees. Lizard Island material possesses the narrowest median paleae as do <i>P. chrysos</i> n. sp. from reefs off Townsville. Heron Island specimens exhibits some broader median paleae as well as the narrower ones; the New Caledonian individual has mainly broad median paleae (cf Fig. 8 D, E & K, L).</p> <p> A New Caledonian specimen is cited as ‘ <i>Paleanotus</i> LI’ in Wiklund <i>et al.</i> (2009). The SMNH specimen on loan for this study is entire so another <i>Paleanotus</i> from the same collection must have been used for the DNA analysis. As there was no morphological description in the paper, a designated species name for the DNA individual is unknown. Future <i>Paleanotus</i> genetic analyses with named species may be able to reveal its identity.</p> <p> A Philippine individual belonging to <i>Paleanotus chrysos</i> species complex was collected from an encrusted habitat similar to habitats of <i>P. chrysos</i> n. sp. from the GBR. Chaetal types are also very similar e.g., slender lateral paleae and spines, and the egg size is the same. However the main and median paleae have even more elevated apices; paleael sculpture is different with no b.l. ribs on main paleae and the median paleae possess a central raised rib. This specimen appears part of the <i>chrysos</i> complex and may prove to be a new species. Slender, pointed laterals, often accompanied by spines in <i>Paleanotus chrysos</i> n. sp. are also seen in the <i>P. silus</i> n. sp. species complex but the main and median paleae shape are different between the species. <i>P. chrysos</i> has been found sympatric with <i>Paleanotus adornatus</i> n. sp. in coral rubble collections from Lizard Island, GBR.</p> <p> <b>Etymology.</b> The species name, <i>chrysos,</i> is derived from the Greek meaning ‘gold’ and refers to the distinctive colour of the notochaetal paleae.</p> <p> <b>Habitat / Distribution.</b> Recorded from the Coral Sea: Lizard Island, reefs off Townsville and Heron Island, GBR, NE coast of Australia and New Caledonia. <i>Paleanotus chrysos</i> n. sp. appears to favour a complex habitat of encrusted coral rubble, red algae, sponges as well as fine algae on sand; depth 2− 30 m.</p>Published as part of <i>Watson, Charlotte, 2015, Seven new species of Paleanotus (Annelida: Chrysopetalidae) described from Lizard Island, Great Barrier Reef, and coral reefs of northern Australia and the Indo-Pacific: two cryptic species pairs revealed between western Pacific Ocean and the eastern Indian Ocean, pp. 707-732 in Zootaxa 4019 (1)</i> on pages 726-729, DOI: 10.11646/zootaxa.4019.1.24, <a href="http://zenodo.org/record/234245">http://zenodo.org/record/234245</a>
Aromatic N versus aromatic F : bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs
No full textThe thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing free energies between natural nucleobases and fluorinated analogs are estimated by potential of mean force calculations. Compared to pairing of AU and GC, pairing involving fluorinated analogs is unfavorable by 0.5–1.0 kcal mol -1. Decomposing the pairing free energies into enthalpic and entropic contributions reveals fundamental differences for Watson–Crick pairs compared to pairs involving fluorinated analogs. These differences originate from direct base–base interactions and contributions of water. Pairing free energies of fluorinated base analogs with natural bases are less unfavorable by 0.5–1.0 kcal mol -1 compared to non-fluorinated analogs. This is attributed to stabilizing C–F…H–N dipolar interactions and stronger N…H–C hydrogen bonds, demonstrating direct and indirect influences of fluorine. 7-methyl-7H-purine and its 9-deaza analog (Z) have been suggested as members of a new class of non-fluorinated base analogs. Z is found to be the least destabilizing universal base in the context of RNA known to date. This is the first experimental evidence for nitrogen-containing heterocylces as bioisosteres of aromatic rings bearing fluorine atoms
Paleanotus adornatus Watson, 2015, n. sp.
No full text<i>Paleanotus adornatus</i> n. sp. <p>(Figs 1 D; 3A −G)</p> <p> <b>Type material.</b> Holotype: NTM W.23677, Western Pacific Ocean, Australia, Queensland, Great Barrier Reef, MacGillivray Reef, 14º39.41’S, 145º29.68’E, CReefs, LI-09-034, coral rubble, 2−12 m, coll. C. Watson, Feb 2009, (27E, L: 3.0 mm, W: 0.75 mm). Paratypes: NTM W.25634, same locality, (4, NE).</p> <p> <b>Other material examined.</b> NTM W.23451, MacGillivray Reef, 14º26.87’S, 145º29.95’E, CReefs, LI-10-028, rubble, 24 m, coll. M. Capa, Aug 2010, (1NE); NTM W.23687, Day Reef, 14º28.33’S, 145º 31.41’E, CReefs, LI- 10-074, clean coralline rubble, 5−10 m, coll. C. Buxton, Sep 2010, (6); NTM W.25635, Day Reef, 14º26.87’S, 145º29.95’E, CReefs, LI-09-048, rubble, 30 m, coll. CReefs, Feb 2009, (1); NTM W.23689, Yonge Reef, north front, 14º34.38’S, 145º 31.13’E, CReefs, LI-10-126, coarse sand, 25 m, coll. C. Buxton, Sep 2010, (1, 35E, L: 3.5 mm, W: 0.7 mm); AM W.47532, Lizard Island, Stn. 76 B-06.15.2, coral block study, coll. P. Hutchings, 1976, (1NE); NMV F.214513, Coral Sea, wreck of HMS <i>Pandora</i>, 11°21.25’S, 143°59.17’E, Stn. NQ 18, 1982, (1E); AM W.23349, North West Ruby Reef, 15º44’S, 145º47’E, rubble from bommie, 9−14 m, coll. I. Loch, Dec 1984, (1, 19E); NTM W.25636, Flora Reef, 16º45’S, 147º43’E, fine rubble, 42 m, coll. C. Buxton, Oct 2010, (1, 13NE, W: 0.7 mm); NTM W.25633, Heron Island, Harrys Bommie, 23º27.62’S, 151º55.77’E, CReefs, HI-10-051, sand & rubble, 12−16 m, coll. C. Buxton, Nov 2010, (2); NTM W.23463, CReefs, HI-10-020A, rubble, coll. C. Buxton, Nov 2010, (1, 19NE, L: 1.00 mm, W: 0.5 mm); NTM W.23191, Heron Channel, Sykes Reef, 23º25.94’S, 151º2.02’E, CReefs, HI-09-018, Nov 2009, (1NE); NTM W.23660, Heron Channel, CReefs, HI-10-055, 23º26.98’S, 151º54.75’E, sand, 30 m, coll. C. Buxton, Nov 2010, (4, NE); NTM W.3021, Arafura Sea, NT, Darwin, Channel Island, <i>Halimeda</i>, LWS, Oct 1985, coll. P. Alderslade, (1, 22E, L: 3.4 mm, W: 0.66 mm); NTM W.13179, Channel Island, under bridge 0.1 m, <i>Halimeda</i> & coral rubble, coll. C. Watson, Dec 1986, (1, 25E, L: 2.1 mm, W: 0.74 mm); AM W.23709, WA, Kimberley, Adele Island, 15º31.7’S, 123º11.61’E, Stn.3 K09, subtidal, 14 Oct 2009, coll. WAM & Woodside Kimberley Survey, (fragments); AM W.47531, Angel Island, Dampier, Stn. WA639, coll. P. Hutchings & L. Avery, 4 Aug 2000, (1, 18NE); NTM W.23725, Outside Channel South, Ningaloo Reef, 22º42.33’S, 113º37’E, CReefs, NR-10-008, 18 m, May 2010, (1, 17NE); NTM W.23187, Ningaloo Reef, off northern passage near Tantabiddi, 21º51.15’S, 113º2.04’E, CReefs, NR13B, coll. N. Bruce, June 2008, (1NE); NTM W.25643, Western Pacific Ocean, Philippines, Luzon, Batangas Bay, Sombrero Island, coral blocks, 17 m, coll. G. San Martin, Dec 2010, (1NE, ovigerous female); CAS 189079, Maricaban Island, Bethelhem, 13º67’N, 120º.84’E, 21 m, coll. C. Piotrowski, May 2011, (1NE); NTM W.25642, Eastern Indian Ocean, Andaman Sea, Thailand, West Ko Similan, 8º38’N, 97º38’E, from live <i>Montipora</i> corals, coll. A. Nateewathana, 15 Feb 1981, (1, 33E, L: 3.4 mm, W: 0.6 mm).</p>Published as part of <i>Watson, Charlotte, 2015, Seven new species of Paleanotus (Annelida: Chrysopetalidae) described from Lizard Island, Great Barrier Reef, and coral reefs of northern Australia and the Indo-Pacific: two cryptic species pairs revealed between western Pacific Ocean and the eastern Indian Ocean, pp. 707-732 in Zootaxa 4019 (1)</i> on page 714, DOI: 10.11646/zootaxa.4019.1.24, <a href="http://zenodo.org/record/234245">http://zenodo.org/record/234245</a>
Sous-facteurs de L(F∞) d'indice 4cos2π/n,n≥3
No full textLet Q be a factor of type II1, λ a number in the Jones discrete series {4cosπ/m:m≥3}, and {ei} the Jones projections associated with λ. Denote by A2n and A1n the finite-dimensional von Neumann algebras generated, respectively, by {1,e2,⋯,en} and {1,e1,⋯,en}, with the corresponding traces. The author shows that, for n sufficiently large, the index of the inclusion An=(Q⊗A2n)∗A2nA1n⊂(Q⊗A2n+1)∗A2n+1A1n+1=An+1 is equal to λ (here ∗ denotes the reduced, amalgamated free product of the algebras in question). Using the random matrix model of Voiculescu, he proves that if Q is the von Neumann algebra L(F∞) of the free group with infinitely many generators, then An is isomorphic to L(F∞).
The two facts together imply the existence, for any λ in the Jones discrete series, of an irreducible subfactor of L(F∞) of index λ. This constitutes the first example of a nonhyperfinite, non-Γ II1 factor such that its Jones invariant is fully computable (the existence of nonirreducible subfactors of L(F∞) for any index ≥4 is a simple consequence of known results)
R. W. Seton-Watson. Britain and the Dictators J.-F. Charvet. L'influence britannique dans la SDN
No full textVaucher Paul. R. W. Seton-Watson. Britain and the Dictators J.-F. Charvet. L'influence britannique dans la SDN. In: Politique étrangère, n°3 - 1938 - 3ᵉannée. pp. 301-302
R. W. Seton-Watson. Britain and the Dictators J.-F. Charvet. L'influence britannique dans la SDN
No full textVaucher Paul. R. W. Seton-Watson. Britain and the Dictators J.-F. Charvet. L'influence britannique dans la SDN. In: Politique étrangère, n°3 - 1938 - 3ᵉannée. pp. 301-302
The use of psoriasis biomarkers, including trajectory of clinical response, to predict clearance and remission duration to UVB phototherapy
No full text\ua9 2021 European Academy of Dermatology and Venereology. Background: Remission duration and treatment response following phototherapy for psoriasis are highly variable and factors influencing these are poorly understood. Objectives: Our primary outcome was to investigate whether selected clinical/serum biomarkers were associated with remission duration, and secondly with psoriasis clearance at the end of phototherapy. In addition, we looked at whether early trajectory of UVB clearance was associated with final clearance outcome. Methods: We performed a prospective cohort study of 100 psoriasis patients, routinely prescribed Narrowband UVB and measured selected clinical and biochemical biomarkers, including weekly PASI (psoriasis area and severity index) scores. Patients were followed up for 18 months. Results: The median time to relapse was 6 months (95% CI 5–18) if PASI90 was achieved, and 4 months (95% CI 3–9) if less than PASI90 was achieved. Achieving PASI100 did not result in prolonged remission. On UVB completion, the median final PASI (n = 96) was 1.0 (IQR 0.5, 1.6) with 78 (81%) achieving PASI75 and 39 (41%) achieving PASI90. Improved PASI90 response was significantly associated with lower BMI, higher baseline PASI, non-smoking status and lower cumulative NbUVB. Serum levels of C-reactive protein (CRP) and vitamin D were not associated with clearance or remission duration. Early treatment response from weeks 2–3 was predictive of final outcome. For example, achieving PASI30 at week 3 was significantly associated with PASI90 at the end of the course [36/77 (51%) vs. 2/24 (8%), P < 0.001]. Conclusions: Raised BMI and positive smoking status predicted poorer phototherapy response. For the first time, we have shown that PASI clearance trajectory over the first 2–3 weeks of UVB, can predict psoriasis clearance. This is an important new step towards developing psoriasis personalized prescribing, which can now be formally tested in clinical trials. These simple clinical measures can be used to inform patient treatment expectations; allowing treatment modifications and/or switching to alternative therapies
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