131 research outputs found
The role and working of reference, or advisory, groups involving disabled people: reviewing the experiences and implications of three contrasting research projects
No full textIncreasingly in recent years, the involvement of disabled people as co-researchers has been regarded as ‘good practice’. This has been informed by growing participatory and emancipatory research paradigms as well as user focused policy imperatives. The benefits of these shifts apply to the research itself (improved definition, direction, applicability and impact), to non-disabled researchers(personal growth and enhanced understanding of the reflexive research process), to people with disabilities involved as researchers or collaborators (personal growth and enhanced opportunities), and (if externally funded) to the funder whose ways of operating are likely to be challenged profoundly. In this paper, Ann Lewis, Sarah Parsons and Christopher Robertson (based at the University of Birmingham), Anthony Feiler, Beth Tarleton and Debby Watson (based at the University of Bristol) and Richard Byers, Jill Davies, Ann Fergusson and Claire Marvin (based at the University of Cambridge) discuss the work of three independent research teams carrying out concurrent projects. The authors share their experiences of trying to take seriously the participation of disabled people in research. All three projects were informed, to a significant degree, by their respective reference groups of disabled people. The work of these groups in each of the three projects is outlined and then discussed in relation to five common themes: formal contracts with members of reference groups; considerations concerning drawing on an established reference group; planning for reference group involvement; style of reference group involvement; and building on good practice
The Making of a Book: The Debby Atwell Project: A Lessonn in Stewardship
No full textVideo accompanying the book, Many Friends, by the children of Peaks Island Elementary School, under the guidance of author/illustrator Debby Atwell. Videography by Don Perry. Music by Peaks Island musicians. Spring 2001.This bookmaking project and the videotaping were funded by a grant from MBNA to the Peaks Island Branch of the Portland Public Library with additional support from Peaks Island Lions Club, Peaks Island School, Peaks Island School PTA, and the Friends of the Peaks Island Library.Running time: 20 minutes.https://digitalcommons.portlandlibrary.com/peaks_vhs/1001/thumbnail.jp
Portfolio of recorded performances and exegesis: Messiaen’s musical language for the jazz pianist - an exploration through performance.
No full textMoving beyond Gunther Schuller’s Third Stream amalgamation of classical and jazz, this study explores whether the musical language of Olivier Messiaen can make a valid contribution to jazz piano performance. Initially, my project sought to answer such questions as: What elements of the musical language of Messiaen already exist in the jazz vocabulary? Am I able to extend this further? What are the timbral structures and pianistic effects within Messiaen’s musical language? What will be the most effective application of Messiaen’s musical language to jazz piano performance? Endeavouring to answer the final question led me to consider such aspects as whether the project should be limited to quoting Messiaen motifs, arranging Messiaen melodies, replacing jazz harmonic structures on standards with examples from Messiaen’s musical language or whether it would be better to approach the research conceptually. The work of Hubert Nuss provided encouraging reassurance that this was not an impossible task. In order to articulate this conception, the initial challenge was to decide how the classical and jazz worlds might meet in a ‘Messiaen’ technique. The approach adopted was similar to that used for undergraduate jazz study, namely, immersion in the piano scores and recordings of Messiaen’s music as well as by live performances. This was followed by the development and assessment of a contrived approach when specific techniques, such as tonal colourings or harmonic structures, were developed through prepared exercises and consciously included in my performance. It was then compared with an intuitive approach when no such precise parameters were established. This submission consists of CD recordings of two public recitals and an exegesis. It documents the development of this Messiaen technique and discusses its application in my performances. It also demonstrates the ways that Messiaen’s musical language can be used within jazz piano performance to provide a colour that distinguishes jazz piano performance in a competitive field.Thesis (M.Mus.) -- University of Adelaide, Elder Conservatorium of Music, 201
Mobile Press-Register sleeve MP0106839
No full textLeah Nicholson, Stephanie Landrum, Wendy Lynd, Gina Danzey, Heather Walker, Elizabeth Prater, Kristin Masters, Tara Greene, Debby Dunn, Brooke Howell Michelle Lynd / (Adams Middle School
Mobile Press-Register sleeve MP0117645
No full textROTC leads cancer survivors on first lap: BC Commission team / Baldwin County / 1) ROTC leads cancer survivors on first lap; 2) BC Commission team: from left Barbara McGowan, Susan Lovett, Lori Ruffin, Monica Cook, Cindy Golden, Peggy Cook, Krystal Hyatt, Tammy Hadley / 3) Elana Carson, Suzanne Cale, Brooke Caldwell, Debby Watson and Abby Hamilton / Relay for Life / [Work order included
The study of Murine double minute-2 (Mdm2) in regulating neuronal activity-dependent protein translation
No full textThe plasticity of synaptic connection is crucial for establishing proper neural circuit excitability throughout development stages, and serves an essential role in maintaining excitatory/inhibitory (E/I) balance in the central nervous system. In this thesis, I discovered potential signaling pathways that contribute to neuronal excitability regulation upon various external stimuli.
In Chapter II, I focused on determining the underlying molecular pathways that elevate neuronal excitability upon activating Group 1 metabotropic glutamate receptors (Gp1 mGluRs). While multiple mechanisms have been identified that contribute to elevating local synaptic translation efficiency, it remains largely unknown how Gp1 mGluR-mediated signaling regulates general protein translation. We identified a novel function of Murine double minute 2 (Mdm2), an ubiquitin E3 ligase, which is involved in the Gp1 mGluR-mediated translational control and activation leads to the elevation of neural activity. Using a fragile X syndrome (FXS) mouse model, we demonstrated this phenomenon is modulated by FMRP-dependent Mdm2 down-regulation. This study provides a possible direction for rescuing the dysregulated Gp1 mGluR signaling observed in fragile X syndrome patients.
In Chapter III, my research focuses on understanding the novel functions of Mdm2 in regulating protein translation under cellular stress conditions. While studies have previously shown that seizures could induce endoplasmic reticulum (ER) stress, I determined how acute ER stress response modulates neuronal excitability and seizure severity. Mechanistically, we found that these beneficial effects are mediated by elevated protein translation, which is triggered by the activation of Mdm2-p53 signaling, during the early ER stress response. Our findings suggest that therapeutic attempts to reduce ER stress in epilepsies may result in worsening seizure activity and therefore caution against inhibition of ER stress as a neuroprotective strategy for epilepsies.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-12-01The student, Dai-Chi (Debby) Liu, accepted the attached license on 2019-10-29 at 10:40.The student, Dai-Chi (Debby) Liu, submitted this Dissertation for approval on 2019-10-29 at 10:41.This Dissertation was approved for publication on 2019-11-01 at 15:52.DSpace SAF Submission Ingestion Package generated from Vireo submission #14504 on 2020-02-28 at 17:21:09Made available in DSpace on 2020-03-02T22:12:11Z (GMT). No. of bitstreams: 2
LIU-DISSERTATION-2019.pdf: 9724667 bytes, checksum: 0ace09570584aa4ab7165035f0941d27 (MD5)
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Previous issue date: 2019-11-01Embargo set by: Seth Robbins for item 113868
Lift date: 2022-03-02T22:12:26Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 113868
Lift date: 2022-03-02T22:15:21Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 113868
Lift date: 2022-03-02T22:18:25Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 113868 on 2022-03-03T10:15:30Z
Organisational culture and quality management system implementation in Indonesian construction companies
No full textThe study of the organisational culture in the construction industry is still in the stage of\ud
debate (Oney-Yazıcı et al., 2007). Despite the complexities involved in measuring the culture\ud
of the construction industry (Tijhuis and Fellows, 2012), this culture is regarded as being\ud
worthy of research, especially in relation to the organisational culture needed to support\ud
quality management systems (Koh and Low, 2008; Watson and Howarth, 2011) and to\ud
improve organisational effectiveness, and therefore, organisational performance (Coffey,\ud
2010; Cheung et al., 2011).\ud
A number of recent studies have examined the construction companies’ organisational\ud
culture within the context of the use of Cameron and Quinn’s Competing Value Framework\ud
(CVF), as well as the use of their Organizational Culture Assessment Instrument (OCAI) as\ud
the conceptual paradigm for the analyses (Thomas et al., 2002; Nummelin, 2006; Oney-\ud
Yazıcı et al., 2007; Koh and Low, 2008). However, there has been little research based on the\ud
use of Cameron and Quinn’s CVF-OCAI tool for identifying types of construction\ud
companies’ organisational culture and their influences on the implementation of QMS-ISO\ud
9001. Research output and information is also very limited relating to the strength of the\ud
companies’ organisational culture driving an effective QMS-ISO 9001 implementation,\ud
affecting the companies’ effectiveness. To rectify these research gaps, the research has been\ud
aimed to study organisational culture types (based on CVF) and their influences on the\ud
implementation of QMS-ISO 9001:2008 principles and elements, which eventually lead to\ud
improved companies’ quality performance. In order to fully examine the status of the QMS\ud
being implemented, the research has studied the relationships of the barriers of QMS\ud
implementation with the implementation of QMS-ISO 9001:2008 principles and elements\ud
and with the business performance of the companies, as well as the examination of the\ud
relationships of the implementation of QMS-ISO 9001:2008 principles and elements with the\ud
companies’ business performance. The research output has been the development of\ud
fundamental and original studies on the study topics, to provide the knowledge for\ud
improvements in Indonesian construction companies’ quality performance and quality\ud
outcomes
The Curtains: On the Private-Public Street Boundary
No full textProbing into the parameters of a ‘wall’, this project seeks to empower the boundary wall in reactivating street life along the private-public street boundary, where front-yards were originally planned but now missing. In Teusaquillo of Bogota, people have regretfully took ‘walls’ as mere devices to define territories. Yet, there are latent potentials embedded in these boundary walls that could support more vibrant streetscape. Unlocked by investigating a ‘wall’ through urban ecology and etymology, findings are translated into an architectural intervention that evokes search for meaningfulness and integration between the school boundary walls and the neighbourhood. As an incremental result from a parallel process of research and design, a new series of ‘urban curtains’ challenges the monotonous definition of school boundary walls which are ubiquitous in Teusaquillo. Various actors would explore their own interpretation of this seam between school and street, by operating each layer of curtain. Built to activate urban life, the ‘urban curtain’ is also advocating a new type of ‘co-operative security’ that initiates public surveillance, in opposition to a passive security device imposed by the school authority. Within this seam, is an inconspicuous yet sensitive testing ground that embodies how the author, as an architect, could craft capacity for an equivocal built environment.Architecture, Urbanism and Building Science
Author, Scientist Shows Sympathy For Jones Coeds
No full textFrom the Rice Thresher Archive, a collection of newspaper articles published in the student newspaper for Rice University. Genre: New
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