16,330 research outputs found
Wang Shuo and the commercialisation of contemporary Chinese culture
Full text linkThis thesis examines the commercialisation of Chinese culture that has taken place over the past twenty years in mainland China. It explores the contribution of Wang Shuo, a cultural figure who straddles different fields of culture, moving from literature to the ultimate mass culture medium of television, this study plots Wang Shuo' s development from educational failure, to business failure, to fiction writer, film & TV editor, film director and cultural critic and analyst. His stories, films, TV series and articles have caused shock-waves throughout national cultural circles as he has transformed the terms of the debate from academic discourse to a validation of the role of the market in the culture field. Although Wang Shuo has not been labelled as a dissident, his approach to the culture market has had a more subversive effect on official ideology that those overt dissidents who have had to live in exile or have been imprisoned. He has utilised the language of official ideology to satirise the authorities, turning the ideology and its supporters into figures of fun. Yet his own goals have been strictly personal and economic ones. The authorities recognize the value of Wang Shuo's work in the cultural market but at the same time distrust his works and place him under strict censorship. Examining the way Wang Shuo and people surround him have succeeded in different fields of cultural achievement is a mirror to understanding the process of the transformation of contemporary Chinese culture from a socialist state-controlled culture to a market-oriented mass culture industry
Isolation and characteri-zation of Bdellvibrio; parasitic to gram-negative fish pathogenic bacterium.
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RDLS-SS-DWT v. 0.9
No full textThis fileset contains the implementation of RDLS-DWT and SS-DWT in JPEG 2000 (RDLS-SS-DWT v. 0.9), which was used in a research described in: R. Starosolski, “Application of reversible denoising and lifting steps to DWT in lossless JPEG 2000 for improved bitrates,” Signal Processing: Image Communication, Vol. 39, Part A, pp. 249-63, DOI: 10.1016/j.image.2015.09.013, 2015 and R. Starosolski, “Skipping selected steps of DWT computation in lossless JPEG 2000 for improved bitrates,” submitted. This software is intended for research purposes only; it is provided "as is"; author makes no warranty of any kind, either express or implied, with respect to this software. <br
Biodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance
No full textKai Dong,1 Yan Yan,2 Pengchong Wang,2 Xianpeng Shi,2 Lu Zhang,2 Ke Wang,2 Jianfeng Xing,2 Yalin Dong1 1Department of Pharmacy, The First Affiliated Hospital of Xi’an Jiaotong University, 2School of Pharmacy, Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China Abstract: In this study, a type of multifunctional mixed micelles were prepared by a novel biodegradable amphiphilic polymer (MPEG-SS-2SA) and a multidrug resistance (MDR) reversal agent (D-α-tocopheryl polyethylene glycol succinate, TPGS). The mixed micelles could achieve rapid intracellular drug release and reversal of MDR. First, the amphiphilic polymer, MPEG-SS-2SA, was synthesized through disulfide bonds between poly (ethylene glycol) monomethyl ether (MPEG) and stearic acid (SA). The structure of the obtained polymer was similar to poly (ethylene glycol)-phosphatidylethanolamine (PEG-PE). Then the mixed micelles, MPEG-SS-2SA/TPGS, were prepared by MPEG-SS-2SA and TPGS through the thin film hydration method and loaded paclitaxel (PTX) as the model drug. The in vitro release study revealed that the mixed micelles could rapidly release PTX within 24 h under a reductive environment because of the breaking of disulfide bonds. In cell experiments, the mixed micelles significantly inhibited the activity of mitochondrial respiratory complex II, also reduced the mitochondrial membrane potential, and the content of adenosine triphosphate, thus effectively inhibiting the efflux of PTX from cells. Moreover, in the confocal laser scanning microscopy, cellular uptake and 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assays, the MPEG-SS-2SA/TPGS micelles achieved faster release and more uptake of PTX in Michigan Cancer Foundation-7/PTX cells and showed better antitumor effects as compared with the insensitive control. In conclusion, the biodegradable mixed micelles, MPEG-SS-2SA/TPGS, could be potential vehicles for delivering hydrophobic chemotherapeutic drugs in MDR cancer therapy. Keywords: reversal of multidrug resistance, reduction-sensitive, disulfide bond, mixed micelles, MCF-7/PTX cell
Locating the External Source of Enforceability: Alliances, Bilateral Investment Treaties, and Foreign Direct Investment
No full textreplication files for wang&youn-ss
Locating the External Source of Enforceability: Alliances, Bilateral Investment Treaties, and Foreign Direct Investment
No full textreplication files for wang&youn-ss
A limited sampling strategy for the estimation of 12-hour cyclosporine neural area under the curve in Chinese cardiac transplant recipients.
No full textThe pathological study of calves with the Tai-Ta No. 1 centrifugal pump as left ventricular assist device (LVAD)
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