2,342 research outputs found
Data from: A study on the Influence of submergence ratio on the transportation of suspended sediment in a partially vegetated channel flow
No full textRiparian or aquatic vegetation thrives with seasons. The understanding of canopies' Submergence-Ratio SR (stems' height to water depth) influence on suspended sediments' transportation is still limited. Thus, Large Eddy Simulations (LES) coupled with the Discrete Phase Method (DPM) are used to investigate the particles' 3-dimensional distribution in a partially vegetated straight channel. The spanwise distribution of particles is quantified by the Probability Density Function (PDF), showing a non-uniformity of particles in time as quantified by the PDF variance. The findings and conclusions: (Ⅰ) With SR rising, the particles' depletion effects exerted by the vegetation-side mixing layer are improved along the interface between vegetated and vegetation-side bare channel region. However, the SR has little effect on the variance of the particles' PDF in the spanwise direction when the mixing layer is fully developed. (Ⅱ) During the developing stage of the over-canopy mixing layer, submerged vegetation with higher SR gain a stronger upwards (vertical) entrainment capability. The case (SR=60%) has a higher sediment concentration than other cases in the fully developed vertical mixing layer region above canopy. (III) The vertical suspension of particles in the vegetation-side bare channel region is analysed. Particles migrating from the vegetated region are entrained into the vegetation-side bare channel region by turbulent structures. Nevertheless, the vertical concentration profile is more uniform in the vegetated region than in the vegetation-side bare channel at the same streamwise location. The cases SR=40% and 60% still have higher sediment concentrations than other cases in the vegetation-side bare channel's upper region.The corresponding author is Dr. Eldad Avital. Mingyang Wang is the first author. Funding provided by: Engineering and Physical Sciences Research CouncilCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100000266Award Number:The datasets are produced mainly based on the numerical simulations, some exprimental data is collected from published literatures
sj-docx-1-cat-10.1177_10760296231157741 - Supplemental material for Evaluation of Platelet Parameters in Patients With Secondary Failure of Platelet Recovery and Cytomegalovirus Infection After Hematopoietic Stem Cell Transplantation
No full textSupplemental material, sj-docx-1-cat-10.1177_10760296231157741 for Evaluation of Platelet Parameters in Patients With Secondary Failure of Platelet Recovery and Cytomegalovirus Infection After Hematopoietic Stem Cell Transplantation by Yujian Zhao, Shuo An, Hongchen Bi and
Xiaoli Luo, Mingyang Wang, Aiming Pang, Erlie Jiang, Yigeng Cao, Yujie Cui in Clinical and Applied Thrombosis/Hemostasis</p
Ji tai 23Na 87Rb fen zi de ji xing chao leng qi ti
No full textPh.D.This thesis describes the creation and collisional investigations of a high density sample of ultracold ground-state dipolar ²³Na⁸⁷Rb molecules. These molecules are produced by transferring weakly-bound Feshbach molecules to the ground state through a two-photon Raman process. To this end, an ultrastable and narrow linewidth Raman laser system is constructed by locking two diode lasers to a dual-wavelength coated high-finesse optical cavity. After identifying the two-photon pathway, a Stimulated Raman adiabatic passage with efficiency up to 93% is achieved, which allows us to produce a sample of absolute ground-state ²³Na⁸⁷Rb molecules with density as high as 6×10¹¹ cm⁻³. An effective electric dipole moment over 1 Debye, the largest ever achieved in ultracold molecules, is also demonstrated by applying a static electric field.Although the absolute ground-state ²³Na⁸⁷Rb molecules are chemically stable, an unexpected fast two-body loss is observed. Thus, collisions of the molecules prepared to different internal states, which is achieved by combining the high-resolution two-photon Raman process with extra microwave pulses, are investigated. Loss rates of the ground-state molecules with different dipolar interaction strength are also measured. These results pave the way toward the investigations of ultracold gases with strong dipolar interactions本論文介紹了高密度基態超冷極性鈉銣分子的製備以及對其碰撞性質的研究。為了把分子從弱束縛費什巴赫態轉移到基態，我們搭建了一套超穩且具備超窄線寬的激光系統。通過合適的雙光子拉曼過程，我們實現了93%的轉移效率，成功製備了密度高達6×10¹¹ cm⁻³的基態超冷鈉銣分子。通過外加靜電場，我們成功誘導基態分子達到1 Debye的等效電偶極矩，這是目前在超冷分子里實現的最大等效電偶極矩。儘管基態鈉銣分子是化學穩定的，我們依然在實驗上觀測到了分子的嚴重損耗。通過對分子內態的超精密操控，我們研究了分子在有化學反應和沒有化學反應發生情況下的損耗行為，並且觀測到了非常相似的動力學過程。此外，我們還研究了在不同偶極相互作用強度下的分子損耗，在超冷溫度下同時觀測到了s分波和d分波的貢獻。雖然這些結果還不足以確定基態分子的損耗機制，我們的成果對極性超冷氣體的研究具有重要意義。Guo, Mingyang = 基態23Na 87Rb分子的極性超冷氣體 / 郭鳴阳."December 2017."23, 87 in title are superscript.Thesis Ph.D. Chinese University of Hong Kong 2018.Includes bibliographical references (leaves 129-156).Abstracts also in Chinese.Title from PDF title page (viewed on 20, April, 2021).Guo, Mingyang = Ji tai 23Na 87Rb fen zi de ji xing chao leng qi ti / Guo Mingyang
sj-pdf-1-cath-10.1177_10760296211068037 - Supplemental material for Efficacy of Recombinant Human Thrombopoietin for the Treatment of Secondary Failure of Platelet Recovery After Allogeneic HSCT
No full textSupplemental material, sj-pdf-1-cath-10.1177_10760296211068037 for Efficacy of Recombinant Human Thrombopoietin for the Treatment of Secondary Failure of Platelet Recovery After Allogeneic HSCT by Yigeng Cao, Mingyang Wang, Biao Shen, Fei Zhao, Rongli Zhang, Xin Chen, Yi He, Weihua Zhai, Qiaoling Ma, Jialin Wei, Yong Huang, Donglin Yang, Aiming Pang, Sizhou Feng, Erlie Jiang and Mingzhe Han in Clinical and Applied Thrombosis/Hemostasis</p
Recommended from our members
Dietary Patterns and Major Chronic Diseases
No full textDietary improvement may lower the risk of developing chronic diseases and associated mortality. Despite the existence of several disease-oriented dietary recommendations, the superior diets for general health and specific disease such as colorectal cancer have not been determined. In addition, it is unknown whether and how risk factors including dietary factors influence the malignant transformation and metastasis of colorectal cancer prior to diagnosis. We attempted to address these questions using data from the Nurses’ Health Study, NHS II, and Health Professionals Follow-up Study.
In Chapter 1, we comprehensively examined the associations of 17 dietary patterns with the risk of colorectal cancer. Our results suggest that colorectal cancer was most strongly associated with diets reflecting hyperinsulinemia, chronic inflammation, Western style, and adherence to the Dietary Approaches to Stop Hypertension. These diets demonstrated independent associations with colorectal cancer after adjusting for the dietary score based on the World Cancer Research Fund/American Institute of Cancer Research recommendations, indicating that dietary recommendations can be further optimized to maximize their effects in preventing colorectal cancer.
In Chapter 2, we assessed two mechanism-based diets and six diets based on dietary recommendations for major chronic diseases. We found that maintaining a healthy diet was generally associated with a decreased risk of major chronic disease, defined as a composite outcome of major cardiovascular disease, type 2 diabetes, and cancer. Among the eight dietary patterns examined in this study, those reflecting low insulinemic, low inflammatory, and diabetes risk reduction diet may confer the largest risk reduction for various chronic diseases. These findings suggest that diets implicated in insulin and inflammation pathways may guide future dietary guidelines to optimize the health benefits of dietary modification
In Chapter 3, we investigated the associations of 34 prediagnostic risk factors with lethal colorectal cancer, defined as tumors at stage IV at diagnosis or caused cancer-associated death within five years of diagnosis. Our findings suggest several dietary and lifestyle factors may be targeted early before diagnosis to reduce CRC mortality in addition to CRC incidence, such as coffee, whole grains, and cereal fiber. The differential associations with lethal endpoints for age, height, a history of lower gastrointestinal endoscopies, and a diet reflecting chronic inflammation provide evidence of etiologic heterogeneity in malignant potential. The lower proportion of distal colon cancer, and higher proportion of non-MSI-high, and KRAS-mutated tumors in lethal cases suggest that the aggressive phenotypes may be reflected in the tumor at diagnosis
Low-Perplexity LLM-Generated Sequences and Where To Find Them
No full textAs Large Language Models (LLMs) become increasingly widespread, understanding how specific training data shapes their outputs is crucial for transparency, accountability, privacy, and fairness. To explore how LLMs leverage and replicate their training data, we introduce a systematic approach centered on analyzing low-perplexity sequences—high-probability text spans generated by the model. Our pipeline reliably extracts such long sequences across diverse topics while avoiding degeneration, then traces them back to their sources in the training data. Surprisingly, we find that a substantial portion of these low-perplexity spans cannot be mapped to the corpus. For those that do match, we quantify the distribution of occurrences across source documents, highlighting the scope and nature of verbatim recall and paving a way toward better understanding of how LLMs training data impacts their behavior.EPF
The Applications of Photo-mediated Ultrasound Therapy in Vascular Diseases
No full textThe formation of new blood vessels can be associated with various pathological conditions requiring clinical interventions, including blinding eye diseases, tumor metastasis, and skin capillary malformation. We developed a hybrid cavitation-based anti-vascular technique using synchronized nanosecond laser pulses and ultrasound bursts, termed photo-mediated ultrasound therapy (PUT). By precisely controlling the spatiotemporal synchronization between the nanosecond laser pulse induced photoacoustic waves and the second source of ultrasound bursts, selective cavitation can be induced within blood vessel. The resulting shear stress, circumferential stress, and microjets from micro-cavitation led to vasocontraction and blood clot formation for therapeutic effect noninvasively.
This dissertation focuses on preclinical studies on the applications of PUT on two types of vascular diseases: capillary vascular malformation with overgrowth in dermatology and choroidal neovascularization in ophthalmology. A common methodological pipeline was employed for both applications. First, a fully integrated prototype system including laser system, focused ultrasound system, and additional optomechanical design was developed to achieve efficient coupling of laser and ultrasound into the vascular lesions of in vivo animal models. Spatiotemporal synchronization between photoacoustic and focused ultrasound waves was achieved through designing precise timing diagrams. Secondly, various optical imaging modalities, including optical coherence tomography and fundus microscopy, were self-built or upgraded from off-shelf equipment to assess therapy efficacy both intraoperatively and postoperatively. Finally, immunohistochemistry and histopathological analyses were conducted to validate treatment outcomes and serve as the ground truth for evaluations.
In addition to the non-invasive, non-thermal, and high-precision nature of PUT, the results of this study highlight its substantial potential to address current clinical limitations. In the in vivo chicken wattle hypervascularity model, PUT effectively treated vasculature up to a depth of 3 mm in dermis. This is achieved by leveraging ultrasound’s good penetration capabilities, thus bypassing the 1.5 mm depth limitation of pulsed dye laser treatments commonly used in dermatology clinics. In the in vivo rabbit choroidal neovascularization model, PUT successfully stopped vascular leakage without significantly damaging neurosensory tissue, using a laser fluence of 85 mJ/cm² at 1064 nm. This is in contrast to the 50 J/cm² at 689 nm required for standard photodynamic therapy in ophthalmology clinics. These findings underscore PUT's translational potential for clinical interventions in treating vascular diseases in both dermatology and ophthalmology.PhDBiomedical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/196001/1/mingyanw_1.pd
Leptonetela lineata Wang & Li 2011, sp. nov.
No full textLeptonetela lineata sp. nov. Figs 20–23, 72 Type material. Holotype: male (IZCAS), Mingyang Cave, Xingtian Village, Pengzha Town, Xingyi [25°26´N, 105°11´E], Guizhou, China, 27 June 2006, H. Chen leg. Paratypes: 5 females, same data as holotype. Etymology. The specific name is from Latin word, “linea”, meaning “line”, and refers to the line-like anterior margin of atrium in the female; adjective. Diagnosis. This new species is similar to L. tongzi Lin & Li 2010 and L. chiosensis sp. nov., but can be distinguished from L. tongzi by the presence of eight promarginal cheliceral teeth and five small retromarginal teeth (Fig. 23C); five spines retrolateral of male palpal tibia, with the basal two equal length and strong, the distal three situate in triangular (Figs 20D, 22B); from L. chiosensis sp. nov. by the presence of eight promarginal cheliceral teeth and five small retromarginal teeth (Fig. 23C); the absence of median apophysis; the distinct shape of conductor in the male (Figs 20B, 23D); and the line-like anterior margin of atrium in the female (Figs 21C, 23B). Description. Male (holotype): total length 2.25 (Fig. 20A). Prosoma 0.90 long, 0.87 wide. Opisthosoma 1.25 long, 1.00 wide. Sternum 0.62 long, 0.55 wide. Prosoma yellowish, with a pair of setae prolateral of PLE. Median groove needle-shaped, brown. Cervical grooves and radial furrow distinct, brown. Eyes six, reduced to white spots, eye measurements: ALE 0.04, PLE 0.05, PME 0.05; ALE-PME 0.12, PLE-PLE 0.06, PLE-PME 0.10; AER 0.08, PER 0.16. Clypeus 0.12 high, slightly sloped anteriorly. Chelicera (Fig. 23C) dark yellow, with eight promarginal teeth and five small retromarginal teeth. Endites and labium dark yellow. Sternum and legs yellowish. Leg measurements: I 10.90 (3.00, 0.30, 3.50, 2.50, 1.60); II 8.40 (2.40, 0.30, 2.50, 1.80, 1.40); III 7.32 (2.25, 0.25, 2.10, 1.65, 1.10); IV 8.95 (2.50, 0.30, 2.60, 2.25, 1.30). Leg formula: I-IV-II-III. Femur I II with one long spine dorsally (position 0.3). Femur III IV with two long spines dorsally (0.3 and 0.6). Male palp (Figs 20C–D, 22A–B): tibia with three trichobothria dorsally, one long seta and five spines retrolaterally, with the basal two spines equal length and strong, the distal three situate in triangular; middle part of tarsus with an earlobe-shaped process, which decorated with a short spine; tarsus with three long spines distally. Tip of the bulb (Figs 20B, 23D): median apophysis absent, conductor lamellar, embolus triangular. Female (one of the paratypes): total length 3.00 (Figs 21A–B). Prosoma 1.25 long, 1.00 wide. Opisthosoma 1.90 long, 1.60 wide. Sternum 0.62 long, 0.60 wide. Prosoma brown, opisthosoma yellow. Clypeus 0.25 high. Eye measurements: ALE 0.05, PLE 0.04, PME 0.04; ALE-PME 0.14, PLE-PLE 0.08, PLE-PME 0.08; AER 0.10, PER 0.16. Leg measurements: I 9.35 (2.75, 0.30, 2.80, 2.00, 1.50); II 7.25 (2.25, 0.30, 2.00, 1.60, 1.10); III 6.55 (2.00, 0.25, 1.80, 1.50, 1.00); IV 8.45 (2.50, 0.30, 2.40, 2.00, 1.25). Internal genitalia (Figs 21C, 23B) with a pair of spermathecae and sperm ducts; anterior margin of atrium line shaped. Variation. Total length: females 2.60–3.10 (n = 5). Distribution. China (Guizhou) (Fig. 72).Published as part of Wang, Chunxia & Li, Shuqiang, 2011, 2841, pp. 1-90 in Zootaxa 2841 on page
Battery charging and discharging research based on the interactive technology of smart grid and electric vehicle
No full text- …
