55,122 research outputs found

    Ms. Courtney Chartier, RWWL AUC, August 2011

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    This video is a conversation with Ms. Courtney Chartier. Ms. Chartier talks about her work on the "New Georgia Encyclopedia" and "Online Voter Education Project." Andrea Jackson, AUC Woodruff Library, is the interviewer

    Ms. Neely Terrell, RWWL AUC, March 2012

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    This video is a conversation with Ms. Neely Terrell. Ms. Terrell talks about her book, "Super Singles Activate". Anthony Kinsey and Jahnesta Horney, AUC Woodruff Library, are the interviewers

    sj-docx-2-tct-10.1177_15330338211045496 - Supplemental material for The Clinical Significance of RMI2 in Hepatocellular Carcinoma

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    Supplemental material, sj-docx-2-tct-10.1177_15330338211045496 for The Clinical Significance of RMI2 in Hepatocellular Carcinoma by Bin Zheng, MS, Heng Wang, MS, Jin-xue Wang, MS, Zheng-hong Liu, MS, Pu Zhang, MD, Dahong Zhang and MD in Technology in Cancer Research & Treatment</p

    sj-pdf-1-tct-10.1177_15330338211045496 - Supplemental material for The Clinical Significance of RMI2 in Hepatocellular Carcinoma

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    Supplemental material, sj-pdf-1-tct-10.1177_15330338211045496 for The Clinical Significance of RMI2 in Hepatocellular Carcinoma by Bin Zheng, MS, Heng Wang, MS, Jin-xue Wang, MS, Zheng-hong Liu, MS, Pu Zhang, MD, Dahong Zhang and MD in Technology in Cancer Research & Treatment</p

    Angela Wang Interview

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    Angela Wang (Class of 2018) was interviewed by Laurence Lundy via the Zoom internet-based video conferencing software on June 16th, 2020. She grew up in the wealthy, white majority Dallas suburb of Flower Mound and attended predominantly white schools. She majored in biochemistry at SMU, where she also became interested in human rights and active in the LGBTQ+ community. Ultimately, Ms. Wang received a Bachelor's of Science and a Bachelor's of Arts in Biochemistry and Human Rights. She had an internship in Chennai, India, with Unite for Sight, where she helped conduct eye exam screenings related to cataracts. During her stay, she was struck by the disparity in wealth and resources between various sectors of Indian society. She also was an intern at the Dallas Area Rape Crisis Center and studied abroad in Thailand. She found friends through Spectrum (an LGBTQ+ group), Mustang Heroes, and the President's Scholars Program, as well as the multicultural sororities and fraternities and the Asian clubs. She discusses the Black@SMU movement, the Trump election, and various examples of what she perceived as SMU's lukewarm approach to addressing racism during her time as a student. At the time of the interview, Ms. Wang was attending UT Southwestern as a graduate student in medicine

    LC-MS/MS Data from Analysis of Bacteriochlorophylls

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    This data set contains LC-MS/MS analyses of various extracted esterified bacteriochlorophylls. Methods and data are described in the publication (Wang et al., 2014). All .raw files are from a Thermo instrument and can be opened with Xcalibur software by Thermo. Alternatively, files may be opened using publically available software: MZmineThis work was partly supported by funds from the NSF Plant Genome Research Program grant IOS-1238812Hegeman, Adrian Daniel; Freund, Dana M.; Tang, Joseph, K.. (2015). LC-MS/MS Data from Analysis of Bacteriochlorophylls. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/172269

    Ms. Felesha Love, Spelman College, January 2016

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    This video is a conversation with Felesha Love. Ms. Love talks about her book, "Brave Leap to Freedom: Integrating Mind, Body, and Spirit to Cultivate Healthy Relationships". Jordan Moore, AUC Woodruff Library, is the interviewer

    DecoMetDIA: Deconvolution of Multiplexed MS/MS Spectra for Metabolite Identification in SWATH-MS-Based Untargeted Metabolomics

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    SWATH-MS-based data-independent acquisition mass spectrometry (DIA-MS) technology has been recently developed for untargeted metabolomics due to its capability to acquire all MS2 spectra with high quantitative accuracy. However, software tools for deconvolving multiplexed MS/MS spectra from SWATH-MS with high efficiency and high quality are still lacking in untargeted metabolomics. Here, we developed a new software tool, namely, DecoMetDIA, to deconvolve multiplexed MS/MS spectra for metabolite identification and support the SWATH-based untargeted metabolomics. In DecoMetDIA, multiple model peaks are selected to model the coeluted and unresolved chromatographic peaks of fragment ions in multiplexed spectra and decompose them into a linear combination of the model peaks. DecoMetDIA enabled us to reconstruct the MS2 spectra of metabolites from a variety of different biological samples with high coverages. We also demonstrated that the deconvolved MS2 spectra from DecoMetDIA were of high accuracy through comparison to the experimental MS2 spectra from data-dependent acquisition (DDA). Finally, about 90% of deconvolved MS2 spectra in various biological samples were successfully annotated using software tools such as MetDNA and Sirius. The results demonstrated that the deconvolved MS2 spectra obtained from DecoMetDIA were accurate and valid for metabolite identification and structural elucidation. The comparison of DecoMetDIA to other deconvolution software such as MS-DIAL demonstrated that it performs very well for small polar metabolites. DecoMetDIA software is freely available at https://github.com/ZhuMSLab/DecoMetDIA

    DecoMetDIA: Deconvolution of Multiplexed MS/MS Spectra for Metabolite Identification in SWATH-MS-Based Untargeted Metabolomics

    No full text
    SWATH-MS-based data-independent acquisition mass spectrometry (DIA-MS) technology has been recently developed for untargeted metabolomics due to its capability to acquire all MS2 spectra with high quantitative accuracy. However, software tools for deconvolving multiplexed MS/MS spectra from SWATH-MS with high efficiency and high quality are still lacking in untargeted metabolomics. Here, we developed a new software tool, namely, DecoMetDIA, to deconvolve multiplexed MS/MS spectra for metabolite identification and support the SWATH-based untargeted metabolomics. In DecoMetDIA, multiple model peaks are selected to model the coeluted and unresolved chromatographic peaks of fragment ions in multiplexed spectra and decompose them into a linear combination of the model peaks. DecoMetDIA enabled us to reconstruct the MS2 spectra of metabolites from a variety of different biological samples with high coverages. We also demonstrated that the deconvolved MS2 spectra from DecoMetDIA were of high accuracy through comparison to the experimental MS2 spectra from data-dependent acquisition (DDA). Finally, about 90% of deconvolved MS2 spectra in various biological samples were successfully annotated using software tools such as MetDNA and Sirius. The results demonstrated that the deconvolved MS2 spectra obtained from DecoMetDIA were accurate and valid for metabolite identification and structural elucidation. The comparison of DecoMetDIA to other deconvolution software such as MS-DIAL demonstrated that it performs very well for small polar metabolites. DecoMetDIA software is freely available at https://github.com/ZhuMSLab/DecoMetDIA

    DecoMetDIA: Deconvolution of Multiplexed MS/MS Spectra for Metabolite Identification in SWATH-MS-Based Untargeted Metabolomics

    No full text
    SWATH-MS-based data-independent acquisition mass spectrometry (DIA-MS) technology has been recently developed for untargeted metabolomics due to its capability to acquire all MS2 spectra with high quantitative accuracy. However, software tools for deconvolving multiplexed MS/MS spectra from SWATH-MS with high efficiency and high quality are still lacking in untargeted metabolomics. Here, we developed a new software tool, namely, DecoMetDIA, to deconvolve multiplexed MS/MS spectra for metabolite identification and support the SWATH-based untargeted metabolomics. In DecoMetDIA, multiple model peaks are selected to model the coeluted and unresolved chromatographic peaks of fragment ions in multiplexed spectra and decompose them into a linear combination of the model peaks. DecoMetDIA enabled us to reconstruct the MS2 spectra of metabolites from a variety of different biological samples with high coverages. We also demonstrated that the deconvolved MS2 spectra from DecoMetDIA were of high accuracy through comparison to the experimental MS2 spectra from data-dependent acquisition (DDA). Finally, about 90% of deconvolved MS2 spectra in various biological samples were successfully annotated using software tools such as MetDNA and Sirius. The results demonstrated that the deconvolved MS2 spectra obtained from DecoMetDIA were accurate and valid for metabolite identification and structural elucidation. The comparison of DecoMetDIA to other deconvolution software such as MS-DIAL demonstrated that it performs very well for small polar metabolites. DecoMetDIA software is freely available at https://github.com/ZhuMSLab/DecoMetDIA
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