755 research outputs found
sj-xlsx-5-tar-10.1177_17534666231217798 – Supplemental material for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes
No full textSupplemental material, sj-xlsx-5-tar-10.1177_17534666231217798 for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes by Chengbin Wang, Jie Hua, Xiaopu He, Liang Chen and Shuhan Lv in Therapeutic Advances in Respiratory Disease</p
sj-xlsx-4-tar-10.1177_17534666231217798 – Supplemental material for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes
No full textSupplemental material, sj-xlsx-4-tar-10.1177_17534666231217798 for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes by Chengbin Wang, Jie Hua, Xiaopu He, Liang Chen and Shuhan Lv in Therapeutic Advances in Respiratory Disease</p
sj-docx-1-tar-10.1177_17534666231217798 – Supplemental material for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes
No full textSupplemental material, sj-docx-1-tar-10.1177_17534666231217798 for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes by Chengbin Wang, Jie Hua, Xiaopu He, Liang Chen and Shuhan Lv in Therapeutic Advances in Respiratory Disease</p
sj-xlsx-3-tar-10.1177_17534666231217798 – Supplemental material for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes
No full textSupplemental material, sj-xlsx-3-tar-10.1177_17534666231217798 for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes by Chengbin Wang, Jie Hua, Xiaopu He, Liang Chen and Shuhan Lv in Therapeutic Advances in Respiratory Disease</p
sj-xlsx-2-tar-10.1177_17534666231217798 – Supplemental material for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes
No full textSupplemental material, sj-xlsx-2-tar-10.1177_17534666231217798 for A diagnostic model for distinguishing between active tuberculosis and latent tuberculosis infection based on the blood expression profiles of autophagy-related genes by Chengbin Wang, Jie Hua, Xiaopu He, Liang Chen and Shuhan Lv in Therapeutic Advances in Respiratory Disease</p
Characterization of typical airborne fibrous particles and their aerodynamic removal
No full textSubmission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-04-06 without embargo termsThe student, Chengbin Zhang, accepted the attached license on 2021-12-09 at 16:26.The student, Chengbin Zhang, submitted this Thesis for approval on 2021-12-09 at 16:27.This Thesis was approved for publication on 2021-12-10 at 14:25.DSpace SAF Submission Ingestion Package generated from Vireo submission #17440 on 2022-04-06 at 17:11:16Made available in DSpace on 2022-04-29T21:35:54Z (GMT). No. of bitstreams: 2
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Previous issue date: 2021-12-10Common fibers such as cotton, cottonwood seeds, and dryer lint can severely harm human health and equipment operation. In large quantities, fibers can clog air intakes and filters on equipment and machinery. Clogged air intakes and filters will lower efficiency, increase energy usage, causing overheating, premature failure, or explosions. Fibers can cause adverse health effects, from mild skin irritations to respiratory system impairment and suffocation. Fibers can stay airborne easily and travel a great distance. Small particles such as dust, bacteria, and viruses can attach to the fibers. However, there is a lack of information on the aerodynamic properties of such fibrous particles, which is critical for the proper design of air filtering systems such as HVAC systems and vehicles that encounter these particles.
This research aims to characterize some commonly found fibrous particles' physical and aerodynamic properties and then develop and evaluate air cleaning prototypes to remove particles automatically from an air stream. The prototypes were designed based on the principle of a unique uniflow aerodynamic cyclone - the Deduster, developed at the Environment-Enhancing Energy Laboratory (E2-E Lab) led by Dr. Yuanhui Zhang at the University of Illinois at Urbana Champaign (UIUC)
Various fibrous particle samples were collected and categorized into groups, including cotton, eastern cottonwood seeds, dandelions, grass residue (leaves), household dryer lint, Canada goose down feathers, and dog hairs. These particles are widely present, known to cause issues mentioned, and often caught on filters. The density of each sample group was measured using an analytical balance and a helium gas pycnometer. A distribution of aerodynamic diameters for each group was obtained by measuring particle settling velocity in a calm-air settling chamber. Conversions of dynamic shape factors and volume equivalent diameters were performed but only limited to Canada goose down feathers and grass residues due to their larger sizes.
Several prototypes were developed by employing a sensitivity analysis on design parameters in established theoretical equations. A testbed was developed to measure the two most important factors: particle separation efficiency and pressure drop across the prototype. Six Deduster prototypes were modeled using CAD software and manufactured by a high-resolution stereolithography (SLA) 3D printer. Various computational analyses on the designs were performed, including Computational Fluid Dynamics (CFD) analysis and Finite Element Analysis (FEA). The particle separation efficiency of each prototype was performed by gravimetric analysis using standard hydrated lime particles with previously determined properties and size distribution. The two key performance indicators: particle separation efficiency and pressure drop, were tested for all the prototypes under different air flow rates and dust load conditions.
The experimental evaluations were conducted in the Bioenvironmental and Structural System Laboratory (BESS Lab) at UIUC. Results revealed discrepancies compared to theoretical predictions. In all experimental measurements but one, the theoretical calculations underpredicted the pressure drops of the prototypes. The gravimetric analysis showed approximately 90% or higher particle removal
CUHK electronic theses & dissertations collection
No full textCo-culture of eosinophils and BEAS-2B cells was found to increase the release of cytokine IL-6 and chemokines MIG, MCP-1, IL-8 and IP-10 and up-regulate the corresponding genes expression in BEAS-2B cells or eosinophils. Interaction of eosinophil-BEAS-2B cells could also elevate adhesion molecules ICAM-1, VCAM-1, ICAM-3, and CD49d expression on the surface of BEAS-2B cells, and CD18 and ICAM-3 on eosinophils, and up-regulate ICAM-1 gene expression in BEAS-2B cells. Lipopolysaccharide (LPS) and tumor necrosis factor (TNF)-alpha could induce or further induce ICAM-1 expression on eosinophils and BEAS-2B cells upon their interaction. Moreover, activities of both NF-kappaB and p38 MAPK in BEAS-2B cells were markedly elevated after co-cultured with eosinophils.Freshly isolated eosinophils from human peripheral blood and confluent BEAS-2B cells were co-cultured together in tissue culture plate for a pre-determined time period. Cytokines including interleukin (IL)-1beta, IL-2, IL-4, IL-6, IL-10, IL-12p70, tumor necrosis factor (TNF)-alpha, and interferon (IFN)-gamma and chemokines regulated upon activation normal T cell expressed and secreted (RANTES), monokine induced by interferon-gamma (MIG), monocyte chemoattractant protein (MCP)-1, IL-8, and interferon inducible protein (IP)-10 in culture supernatant were evaluated by protein array and quantified by cytometric bead array (CBA) kit of Th1/Th2 cytokines, inflammatory cytokines, and human chemokines using flow cytometry and enzyme linked immunosorbent assay (ELISA) kit.In order to investigate the immunopathological mechanism in allergic asthma of eosinophils interacting with bronchial epithelium in inflammation site, a in vitro system of co-culture of human bronchial epithelial cells and eosinophils was set up to mimic the inflammatory reaction.In summary, co-culture of epithelial cells, BEAS-2B cells, and eosinophils could activate NF-kappaB and p38 MAPK signal transduction pathways to induce inflammatory cytokine IL-6, and chemokines IL-8, MCP-1, MIG and IP-10 release in culture supernatant, and up-regulated the expression of surface adhesion molecules ICAM-1, VCAM-1, ICAM-3 and CD49d protein on BEAS-2B, and CD18 and ICAM-3 on eosinophils. (Abstract shortened by UMI.)In this study, co-culture of a human epithelial cell line, BEAS-2B cells, and peripheral eosinophils was adopted as an in vitro model to investigate the effect of interaction of epithelial cells and eosinophils in airways on pathophysiology of asthma.Wang Chengbin."July 2005."Advisers: Wai kei Lam; Chun kwok Wong; Yaping Tian.Source: Dissertation Abstracts International, Volume: 67-07, Section: B, page: 3723.Thesis (Ph.D.)--Chinese University of Hong Kong, 2005.Includes bibliographical references (p. 119-134).Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.Abstract in English and Chinese.School code: 1307
First discovery of troglobitic Paederinae (Coleoptera, Staphylinidae) from China
No full textAn unexpected troglobitic staphylinid is described from a dolomite cave in western China as Domene lizeyui Wang & He, sp. nov. (Coleoptera, Staphylinidae, Paederinae). The habitus of both sexes and important diagnostic features are illustrated. Brief notes on the habitat, biology and taxonomic status of the new species are provided. This is the first discovery of a troglobitic representative of Paederinae from China, the first record of a troglobitic Domene species, and only the third cavernicolous species of Paederinae from eastern Asia
The Rise and Fall of the Cao Kun 曹錕-Wu Peifu 呉佩孚 Faction
No full textWu Peifu was admired as a "Revolutionary general" in the period of the May Fourth Movement. But after only a few years, in the period of the National Revolution, he became the biggest counter revolutionary, and was defeated by the National Revolutionary Army. What brought about this military-political fall of Wu Peifu? By introducing the idea of a 'Strategy of Unifying China' and inquiring into changes in it, this essay attempts to answer this question. The author's conclusions are as follows: The Wang Chonghui 王寵惠 cabinet which Wu Peifu supported collapsed at the end of November 1922. This was the result of the coup d'etat in which Cao Kun, Wang Chengbin 王承斌 and Feng Yuxiang 馮玉祥 formed a united front against Wu Peifu. The collapse lead to a change in the strategy. And this change brought about a complete retrogression of the Cao Kun-Wu Peifu faction into a warlord faction of old type
Vaccine
No full textBackgroundTwo-dose varicella vaccination has been available in Beijing since 2012 in the private sector. We investigated a varicella outbreak in a highly vaccinated elementary school population.MethodsA cohort study was carried out and a varicella case was defined as an acute onset of generalized maculopapulovesicular rash without other apparent cause in a student attending the school from March 29 through May 17, 2015. Breakthrough varicella was defined as varicella >42 days after the last vaccine dose among both 1- or 2-dose varicella vaccine recipients. Vaccination information was collected from immunization records; information on prior varicella and clinical presentations was collected by surveying students\u2019 parents.ResultsOf the 1056 students in the school, 1027 (97.3%) reported no history of varicella. Prior to the outbreak, 98.6% of students had received 651 dose of varicella vaccine, and most (63.2%) students received two doses. Twenty varicella cases were identified for an overall attack rate of 2.0%. Half of the cases occurred in the classroom of the index case-patient, a two-dose recipient who was not isolated after symptom onset. Breakthrough varicella accounted for 95% of cases (19/20) with attack rates of 14.3% (1/7), 1.6% (6/362) and 2.0% (13/649) among unvaccinated, one-dose, and two-dose students, respectively. Most case-patients (18/20, 90%) had <50 lesions. No difference in clinical presentations was found between one-dose and two-dose recipients with breakthrough varicella.ConclusionModerate two-dose varicella vaccine coverage was insufficient to prevent a varicella outbreak. Two-dose recipients with breakthrough varicella are contagious. High two-dose varicella vaccine coverage and timely isolation of cases may be needed for varicella outbreak prevention in the two-dose era.CC999999/Intramural CDC HHSUnited States
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