70 research outputs found
© Hindawi Publishing Corp. UNIQUENESS OF SEMILINEAR ELLIPTIC INVERSE PROBLEM
No full textWe consider the uniqueness of the inverse problem for a semilinear elliptic dif-ferential equation with Dirichlet condition. The necessary and sufficient condition of a unique solution is obtained. We improved the results obtained by Isakov and Sylvester (1994) for the same problem. 2000 Mathematics Subject Classification: 35R30, 35J60. 1. Introduction. Isakov and Sylvester considered in [3] the problem of uniquely determining a in the following semilinear elliptic Dirichlet problem: −∆u+a(x,u) = 0, x ∈Ω, (1.1) u|∂Ω = g ∈W 2−1/p,p(∂Ω), (1.2) whereΩ ⊂Rn (n ≥ 3) is a bounded domain and its boundary ∂Ω ∈ C2,α. Denot
Uniqueness of semilinear elliptic inverse problem
No full textWe consider the uniqueness of the inverse problem for a
semilinear elliptic differential equation with Dirichlet
condition. The necessary and sufficient condition of unique
solution is obtained. We improved the results obtained by Isakov
and Sylvester (1994) for the same problem
PMRD: a curated database for genes and mutants involved in plant male reproduction
No full textBACKGROUND: Male reproduction is an essential biological event in the plant life cycle separating the diploid sporophyte and haploid gametophyte generations, which involves expression of approximately 20,000 genes. The control of male reproduction is also of economic importance for plant breeding and hybrid seed production. With the advent of forward and reverse genetics and genomic technologies, a large number of male reproduction-related genes have been identified. Thus it is extremely challenging for individual researchers to systematically collect, and continually update, all the available information on genes and mutants related to plant male reproduction. The aim of this study is to manually curate such gene and mutant information and provide a web-accessible resource to facilitate the effective study of plant male reproduction. DESCRIPTION: Plant Male Reproduction Database (PMRD) is a comprehensive resource for browsing and retrieving knowledge on genes and mutants related to plant male reproduction. It is based upon literature and biological databases and includes 506 male sterile genes and 484 mutants with defects of male reproduction from a variety of plant species. Based on Gene Ontology (GO) annotations and literature, information relating to a further 3697 male reproduction related genes were systematically collected and included, and using in text curation, gene expression and phenotypic information were captured from the literature. PMRD provides a web interface which allows users to easily access the curated annotations and genomic information, including full names, symbols, locations, sequences, expression patterns, functions of genes, mutant phenotypes, male sterile categories, and corresponding publications. PMRD also provides mini tools to search and browse expression patterns of genes in microarray datasets, run BLAST searches, convert gene ID and generate gene networks. In addition, a Mediawiki engine and a forum have been integrated within the database, allowing users to share their knowledge, make comments and discuss topics. CONCLUSION: PMRD provides an integrated link between genetic studies and the rapidly growing genomic information. As such this database provides a global view of plant male reproduction and thus aids advances in this important area.Xiao Cui, Qiudao Wang, Wenzhe Yin, Huayong Xu, Zoe A Wilson, Chaochun Wei, Shenyuan Pan, and Dabing Zhan
Bentian Chengzhi dui Zhongguo jing xue cheng li shi de yan jiu yu gong xian =: Honda Shigeyuki’s study of the early formation of Chinese classics and its contribution
No full textPh.D.Honda Shigeyuki (1882-1945) was one of the representative second-generation scholars of the Kyōto School of Sinology. He was well-versed in the history of Chinese Confucian Classics, the history of Chinese Philosophy and also Chinese art culture. His work Shina Keigaku Shi Ron (《支那經學史論》) is an important work that utilizes positivism method to examine the history of Confucian Classics among the Kyōto School of Sinology,and it has had a profound influence on both China and Japan’s study of Confucian Classics. In collaboration with Ojima Sukema (1886-1966) and Aoki Masaru (1887-1964), he founded the Shinagaku-sha (the Society of Chinese Studies, 支那學社) and the journal Shinagaku (The Journal of Chinese Studies, 支那學報), both of them were important in Sinology study in modern Japan. Despite his significant study on the history of Confucian Classics and crucial role in the Kyoto School’s scholarly activies, Honda has not yet received much academic attention. This research will be the first scholarly attempt to investigate Honda Shigeyuki’s academic life and scholarship through an in-depth analysis of his works.Situating his view on “Yu-Shamanism”(巫) as the origin of Confucian Classics, with a historical context and employing current scholarship of Confucian history and Sino-Japanese intellectual exchange, this paper aims to explore the formation of Honda Shigeki’s thought on Confucianism and China. It also sheds light on the deeper understanding of the Kyoto School of Sinology.本田成之（1882-1945）是日本京都學派「支那學」第二代學者代表之一。他對中國經學史、哲學史及文化藝術研究皆有成就。其《支那經學史論》（1927）是京都支那學派學者運用實證主義方法對中國經學史進行整理的代表作，對於中日兩國的中國經學史研究均有深遠影響。他與青木正兒（1887-1964）及小島祐馬（1881-1966）一起創辦支那學社及社刊《支那學》雜誌（1920-1947）是近代京都學派中國學研究的主要學術陣地。然本田成之這個當時處於京都支那學核心的人物及其學術卻一直未得到學界的重視。本研究擬以本田的中國經學史研究為突破口，通過對原始文獻的深入分析，運用比較的方法，將本田置於近代中日經學史研究這一連貫的學術脈絡中，嘗試對本田成之的生平經歷、學術特點做開拓性調查，希望呈現一個比較完整的本田成之像，并探究近代日本學人在中日關係緊張的社會背景下對於中國和中國文化的思考；另一方面通過對本田的經學史研究，管窺京都支那學內部的互動與傳承關係，以及近代中日知識分子在經學史研究方面的相互影響。本田成之的主要貢獻在於對經學起源的探討。他繼承狩野直喜和內藤湖南的學說，以「巫」與「史」為關鍵詞構建中國上古祭祀文化體系，以探討經學起源以及「六經」的成書年代以及各部經書作者的可能性。其研究脫傳統今古文學之桎梏，以史學考證之方法研究經學成立史，給予諸子之學、讖緯之學以與經學同等的價值，顯示京都支那學派文、史、哲三位一體的研究的特點。從本田成之的經學史研究可見近代日本由「漢學」向「中國學」（支那學）的學術變化。藉助本田成之「異域之眼」亦可探究中國傳統文化的主線——經學的現代性，及經學史在當代的研究趨向。林超純.Parallel title from added title page.Thesis Ph.D. Chinese University of Hong Kong 2018.Includes bibliographical references (leaves 138-145).Abstracts in English and Chinese.Title from PDF title page (viewed on July 31, 2020).Lin Chaochun
iGepros: an integrated gene and protein annotation server for biological nature exploration
No full textAbstract Background In the post-genomic era, transcriptomics and proteomics provide important information to understand the genomes. With fast development of high-throughput technology, more and more transcriptomics and proteomics data are generated at an unprecedented rate. Therefore, requirement of software to annotate those omics data and explore their biological nature arises. In the past decade, some pioneer works were presented to address this issue, but limitations still exist. Fox example, some of these tools offer command line only, which is not suitable for those users with little or no experience in programming. Besides, some tools don’t support large scale gene and protein analysis. Results To overcome these limitations, an integrated gene and protein annotation server named iGepros has been developed. The server provides user-friendly interfaces and detailed on-line examples, so most researchers even those with little or no programming experience can use it smoothly. Moreover, the server provides many functionalities to compare transcriptomics and proteomics data. Especially, the server is constructed under a model-view-control framework, which makes it easy to incorporate more functions to the server in the future. Conclusions In this paper, we present a server with powerful capability not only for gene and protein functional annotation, but also for transcriptomics and proteomics data comparison. Researchers can survey biological characters behind gene and protein datasets and accelerate their investigation of transcriptome and proteome by applying the server. The server is publicly available at http://www.biosino.org/iGepros/.</p
Identification of diversity-generating retroelements in host-associated and environmental genomes: prevalence, diversity, and roles
No full textAbstract Background The diversity-generating retroelements (DGRs) are a family of genetic elements that can produce mutations in target genes often related to ligand-binding functions, which possess a C-type lectin (CLec) domain that tolerates massive variations. They were first identified in viruses, then in bacteria and archaea from human-associated and environmental genomes. This DGR mechanism represents a fast adaptation of organisms to ever- changing environments. However, their existence, phylogenetic and structural diversity, and functions in a wide range of environments are largely unknown. Results Here we present a study of DGR systems based on metagenome-assembled genomes (MAGs) from host-associated, aquatic, terrestrial and engineered environments. In total, we identified 861 non-redundant DGR-RTs and ~ 5.7% are new. We found that microbes associated with human hosts harbor the highest number of DGRs and also exhibit a higher prevalence of DGRs. After normalizing with genome size and including more genome data, we found that DGRs occur more frequently in organisms with smaller genomes. Overall, we identified nine main clades in the phylogenetic tree of reverse transcriptases (RTs), some comprising specific phyla and cassette architectures. We identified 38 different cassette patterns and 6 of them were shown in at least 10 DGRs, showing differences in terms of the numbers, arrangements, and orientations of their components. Finally, most of the target genes were related to ligand-binding and signaling functions, but we discovered a few cases in which the VRs were situated in domains different from the CLec. Conclusions Our research sheds light on the widespread prevalence of DGRs within environments and taxa, and supports the DGR phylogenetic divergence in different organisms. These variations might also occur in their structures since some cassette architectures were common in specific underrepresented phyla. In addition, we suggest that VRs could be found in domains different to the CLec, which should be further explored for organisms in scarcely studied environments
Phenotypic Variation in Leaf, Fruit and Seed Traits in Natural Populations of Eucommia ulmoides, a Relict Chinese Endemic Tree
No full textEucommia ulmoides Oliver is a dioecious, pharmaceutically and economically important, and precious relict tree species endemic to China, and has been listed as a key protected tree species of national level II. Phenotypic variation in ten natural populations in some key traits is still obscure. In order to study the relationship between population variation in phenotypic traits and geoclimatic factors, 15 traits were analyzed in 117 female sampled tree from ten natural populations. The results showed that the coefficients of variation for all of the 15 traits widely ranged from 9.7% (fruit vertical diameter) to 49.0% (leaf thickness), with an average of 19.7%. The nested ANOVA revealed plentiful phenotypic variations within and among populations. The variation within population was the main source, with an average proportion of 42.8%, greater than that among the population (16.6%). The 15 traits were reduced to four principal components, which collectively accounted for 70.1% of phenotypic variation among trees. The ten populations were mainly divided into two groups: Group A included eight populations throughout the Wuling Mountains occurring in relatively close proximity to each other, and Group B which comprises two geographically distant populations in mountains further northern. There were significant level correlations between phenotypic differentiation among population of E. ulmoides and both geographic (r = 0.65, p < 0.05) and climatic (r = 0.73, p < 0.01) distance. Step-wise regression indicates average annual temperature and rainfall accounted for most of the phenotypic variation among populations, and mainly associated with differences in leaf, fruit and seed size. These results can have an important implication for genetic improvement, diversity conservation and resource management of the species in the future
Microdeletion of 4p16.2 in Children: A Case Report and Literature Review
No full textCopy number variations (CNV) are thought to play an important role in causing human diseases, including congenital anomalies, psychiatric disorders, and intellectual disabilities. We report here a one-year-old boy presented to our clinic as developmental delay. He presented a birth weight of 4.5 kg, motor delay, mental retardation, mild hypertonia, and some dysmorphic features (mild frontal bossing, hypertelorism, epicanthus, concave nasal ridge, slightly sparse hair, short hands, and mild nail dysplasia). The brain MRI indicated brain abnormalities; the Gross Motor Function Measure-66 score was 23.37; the Gesell test result showed the development quotient was 50, suggesting mental retardation. Chromosomal microarray analysis showed an approximately 97 kb microdeletion at 4p16.2 (4p16.2 CNV), including part of EVC and EVC2 genes, which were associated with Ellis-van Creveld syndrome (EvC) and Weyers acrofacial dysostosis (WAD). This report suggests 4p16.2 microdeletion may be associated with multiple developmental abnormalities, including motor delay and mental retardation
New insight into simultaneous removal of NO and Hg0 on CeO2 modified V2O5/TiO2 catalyst: Nitrate pathway for Hg0 oxidation
No full textHybrid model predictive control of damping multi-mode switching damper for vehicle suspensions
No full textThis paper investigates the design and verification of a hybrid model predictive controller of a damping multi-mode switching damper for application in vehicle suspensions. Since the damping mode switches induce different modes of operation, the vehicle suspension system including this damper poses challenging hybrid control problem. To solve this problem, a novel approach to the modelling and controller design problem is proposed based on hybrid modelling and model predictive control techniques. The vehicle suspension system with the damping multi-mode switching damper is formulated as a mixed logical dynamical model comprising continuous and discrete system inputs. Based on this model, a constrained optimal control problem is solved to manage the switching sequences of the damping mode with respect to the suspension performance requirements. Numerical simulation results demonstrate the effectiveness of the proposed control methodology finally
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